1. Pertussis in Argentina and France.
- Author
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Caro V, Bouchez V, Guiso N, Gatti B, Agosti MR, and Ayala SE
- Subjects
- Argentina epidemiology, Bacterial Typing Techniques, Bordetella pertussis isolation & purification, Electrophoresis, Gel, Pulsed-Field, Evolution, Molecular, Female, France epidemiology, Genotype, Humans, Immunization Schedule, Infant, Infant, Newborn, Male, Vaccination, Whooping Cough microbiology, Bordetella pertussis classification, Bordetella pertussis genetics, Pertussis Vaccine administration & dosage, Whooping Cough epidemiology, Whooping Cough prevention & control
- Abstract
We have studied the epidemiology of pertussis in two countries, Argentina and France, which have similar histories of long-term mass vaccination with a whole-cell vaccine. Both countries display a comparable epidemiology, with an increase of the incidence of the disease in non-vaccinated newborns. We used pulsed-field gel electrophoresis (PFGE) analysis and genotyping to compare Bordetella pertussis clinical isolates recovered in Argentina and France in 2001-2004. The majority of the isolates harbors prn2 allele and belongs to PFGE IVbeta group. Isolates were found to be very similar genetically suggesting a common evolution of the disease in these two countries using the same vaccine.
- Published
- 2007
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