1. Immunomodulatory activities of Cedrela tubiflora leaf aqueous extracts.
- Author
-
Benencia F, Courrèges MC, Nores MM, and Coulombié FC
- Subjects
- Argentina, Cell Division drug effects, Concanavalin A pharmacology, Dose-Response Relationship, Drug, Humans, Leukocytes cytology, Mitogens pharmacology, Neutrophils drug effects, Phagocytosis drug effects, Plant Extracts pharmacology, Plant Lectins, Respiratory Burst drug effects, Adjuvants, Immunologic pharmacology, Complement Activation drug effects, Leukocytes drug effects, Plants, Medicinal
- Abstract
Human peripheral blood monocytes and polymorphonuclear leukocytes treated with leaf aqueous extracts of the Meliaceae tree Cedrela tubiflora showed a diminution in both their phagocytic and respiratory burst activities. Besides, the extract inhibited the proliferation of Concanavalin A stimulated lymphocytes. A decrease in the hemolytic capacity of the human complement was also observed. The significance of the inhibitory effect observed over some components of the human immune system closely related with the inflammatory process is discussed.
- Published
- 1995
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