1. Validation of an Argentine version of Lupus Quality of Life questionnaire.
- Author
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Machado Escobar, M. A., Yacuzzi, M. S., Martinez, R. N., González Lucero, L., Bellomio, V. I., Santana, M., Galindo, L., Mayer, M. M., Barreira, J. C., Sarano, J., Gomez, G., Collado, M. V., Martinez, A., Orozco, M. C., Betancur, G., Dal Pra, F., Sanchez, A., Juarez, V., and Lucero, E. V.
- Subjects
SYSTEMIC lupus erythematosus treatment ,SYSTEMIC lupus erythematosus ,QUALITY of life ,DISEASE duration ,TREATMENT effectiveness ,PUBLIC health ,PATIENTS - Abstract
Objective To determine reproducibility and validity of an Argentine version of the Lupus Quality of Life questionnaire (LupusQoL) and to determine cut-off values in the questionnaire. Materials and methods One hundred and forty-seven systemic lupus erythematosus patients (American College of Rheumatology 1982/1997) were assessed from April 2014 to July 2014. Demographic and socioeconomic variables were collected, as well as SELENA/SLEDAI, Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index Score, comorbidities and treatment data. Patients completed LupusQoL-Argentine version and European Quality of Life Questionnaire (EuroQoL-5D). Internal consistency and reliability were examined. Convergent validity with EuroQoL-5D was assessed through analysis of latent classes, which established homogeneous categories from the responses of each domain of LupusQoL and for the total. Results Out of 147 patients, 93.2% were female, mean age 36.4 ± 11.1 years, mean disease duration 2.7 ± 9 years, mean SELENA/SLEDAI 2.7 ± 3 points. The cut-off point that defined good or bad quality of life was 0.739 for EuroQoL 5D and 63 for LupusQoL. Cut-off values for each LupusQoL domain were also defined, creating two classes in each of them. There was moderate to high concordance to classify quality of life (Kappa = 0.74, 95% confidence interval = 0.54, 0.95). Conclusion The Argentine version of LupusQoL is a valid, reliable and reproducible instrument to assess quality of life. In this study, cut-off points that allow the classification of patients regarding whether they have good or bad quality of life are established for the first time. [ABSTRACT FROM AUTHOR]
- Published
- 2016
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