1. MUC5AC Levels Associated With Respiratory Syncytial Virus Disease Severity.
- Author
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Rajan D, O'Keefe EL, Travers C, McCracken C, Geoghegan S, Caballero MT, Acosta PL, Polack F, and Anderson LJ
- Subjects
- Argentina, Biomarkers analysis, Child, Preschool, Female, Humans, Infant, Infant, Newborn, Male, Nose virology, ROC Curve, Respiratory Syncytial Virus Infections complications, Respiratory Syncytial Virus, Human genetics, Mucin 5AC analysis, Respiratory Syncytial Virus Infections diagnosis, Respiratory Syncytial Virus, Human isolation & purification, Severity of Illness Index
- Abstract
To assess MUC5AC as a biomarker for respiratory syncytial virus (RSV) disease severity, we tested nasal aspirates from RSV+ children with mild, moderate, and severe disease. Levels were significantly higher in those in the severe and moderate groups compared to mild group, indicating MUC5AC may be a useful biomarker for RSV disease severity.
- Published
- 2018
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