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Background & Aims: Hospital malnutrition is a prevalent yet frequently under-recognised condition that is associated with adverse clinical and economic consequences. Systematic reviews from various regions of the world have provided regional estimates of the prevalence of malnutrition and the magnitude of the associated health and economic burden; however, a systematic assessment of the prevalence and consequences of hospital malnutrition in northeast and southeast Asia has not been conducted., Methods: We performed a systematic literature search for articles on hospital malnutrition in 11 Asian countries published in English between January 1, 1997 and January 15, 2018. Studies reporting data on the prevalence, clinical consequences, or economic impact of hospital malnutrition in an adult inpatient population with a sample size ≥30 were eligible for inclusion., Results: The literature search identified 3207 citations; of these, 92 studies (N = 62,280) met the criteria for inclusion. There was substantial variability in study populations and assessment methods; however, a majority of studies reported a malnutrition prevalence of >40%. Malnutrition was associated with an increase in clinical complications, mortality, length of hospitalisation, hospital readmissions, and healthcare costs., Conclusions: Hospital malnutrition is a highly prevalent condition among hospitalised patients in northeast and southeast Asia. Additionally, poor nutritional status is associated with increased morbidity and mortality and increased healthcare costs. Further research aimed at improving the identification and proactive management of hospitalised patients at risk for malnutrition is necessary to improve patient outcomes and alleviate the burden on local healthcare budgets., Competing Interests: Declaration of Competing Interest Dr. Inciong has received honoraria for continuing medical education activities from Abbot, Fresenius Kabi, BBraun, Westmont; Dr. Lam has received a grant from Fresenius Kabi and non-financial support from IQVIA; Dr. Chaudhary, Dr. Hsu, Dr. Joshi, Dr. Seo, Dr. Ungpinitpong, and Dr. Usman have no competing interests to disclose., (Copyright © 2020 The Authors. Published by Elsevier Ltd.. All rights reserved.)