1. Childhood adversity, early-onset depressive/anxiety disorders, and adult-onset asthma.
- Author
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Scott KM, Von Korff M, Alonso J, Angermeyer MC, Benjet C, Bruffaerts R, de Girolamo G, Haro JM, Kessler RC, Kovess V, Ono Y, Ormel J, and Posada-Villa J
- Subjects
- Adolescent, Adult, Adult Survivors of Child Abuse statistics & numerical data, Age of Onset, Americas epidemiology, Anxiety Disorders etiology, Anxiety Disorders psychology, Asia epidemiology, Asthma etiology, Asthma psychology, Causality, Child, Child, Orphaned psychology, Child, Preschool, Cross-Sectional Studies, Depressive Disorder etiology, Depressive Disorder psychology, Divorce, Domestic Violence psychology, Europe epidemiology, Female, Humans, Infant, Male, Parents psychology, Poverty, Risk Factors, Survivors psychology, Anxiety Disorders epidemiology, Asthma epidemiology, Depressive Disorder epidemiology, Life Change Events, Survivors statistics & numerical data
- Abstract
Objectives: To investigate a) whether childhood adversity predicts adult-onset asthma; b) whether early-onset depressive/anxiety disorders predict adult-onset asthma; and c) whether childhood adversity and early-onset depressive/anxiety disorders predict adult-onset asthma independently of each other. Previous research has suggested, but not established, that childhood adversity may predict adult-onset asthma and, moreover, that the association between mental disorders and asthma may be a function of shared risk factors, such as childhood adversity., Methods: Ten cross-sectional population surveys of household-residing adults (>18 years, n = 18,303) assessed mental disorders with the Composite International Diagnostic Interview (CIDI 3.0) as part of the World Mental Health surveys. Assessment of a range of childhood family adversities was included. Asthma was ascertained by self-report of lifetime diagnosis and age of diagnosis. Survival analyses calculated hazard ratios (HRs) for risk of adult-onset (>age 20 years) asthma as a function of number and type of childhood adversities and early-onset (
- Published
- 2008
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