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Management of Be contamination using industrial solid waste or solid waste-derived amendments is not well understood. This study investigated the potential of Australian coal fly ash (CFA), derived synthesized zeolite (SynZ) and chitosan-modified zeolite (ModZ), for Be immobilization at the Little Forest Legacy Waste Site (LFLS), a low-level radioactive waste disposal site near Sydney, Australia. In laboratory simulation experiments, the SynZ and ModZ were separately applied as an amendment to both naturally contaminated soil and simulated contaminated (spiked) soil. Different techniques, including pore water (PW), batch desorption, and microbial activities were assessed to provide insight into immobilization mechanisms. Results revealed that amendment of 2% ModZ in soils, substantially decreased Be concentrations in PW (PW Be ) ranging from 13.3% to 99.5% across all concentrations of Be. In contrast, PW Be increased while using SynZ, which could be attributed to the increased solubility of different organic-inorganic elements in PW. Moreover, batch desorption using Milli-Q water, simulated acid rainwater [H 2 SO 4 /HNO 3  = 60/40, (v/v), and 0.11 M acetic acid solution also revealed similar patterns of Be immobilization as found in PW Be analysis. Soil amendments boosted microbial biomass carbon, and phosphorous (MB C,P ), along with basal respiration (BR CO2 ). This indicates increased microbial activities, which are linked with environmental eco-friendliness. This effect was substantially noticed in ModZ-amended soils, exhibiting up to 22 times higher in BR CO2 values compared to unamended soil. Additionally, reduced PW Be was correlated with soluble organic-inorganic elements, desorbed Be in the batch study, and soil MBc. The differences in behavior between SynZ and ModZ underline the importance of carefully studying the various potential amendment materials and the need to evaluate their performance before application in field situations. This study highlights ModZ's effectiveness in eco-friendly Be immobilization, underlining the role of organic functional groups in zeolite architecture, a key factor in controlling Be in soils., Competing Interests: Declaration of competing interest Authors have no conflict of interest to declare., (Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.)

Objectives: The study aimed at determining the factors that contributed to older people presenting from residential aged care facilities (RACFs) to the emergency department (ED) of a regional Victorian hospital located in MM3 regional area., Methods: Appropriateness of transfer was assessed based on predefined criteria, and associated costs for each presentation were calculated., Design: The study carried out a retrospective review of records between July and December 2021. Data were extracted in a MS Excel spreadsheet and transferred to STATA 15.0 for analysis., Setting: Large regional health service in Victoria., Participants: Residential aged care facilities residents presenting to the ED., Main Outcome Measures: Was transfer appropriate or avoidable, costs associated with avoidable transfer, characteristics of the patient and circumstances relating to presentation to hospital., Results: A total of 448 presentations were recorded, and 85% of residents were >75 years of age. More than 60% of presentations occurred during weekends or after hours, with the most common reason being falls (31.9%). Over half (55.6%) of all presentations were avoidable which incurred a cost of $777 200 in 6 months. In multiple logistic regression, higher ED presentations were observed in residents with no prior GP assessment (OR: 1.47, 95% CI: 1.02-2.11)., Conclusions: Necessary interventions such as preventing falls and increasing primary care access along with improving the quality of advance care directives (ACD) may reduce RACF transfers to the regional ED. To the best of our knowledge, this is the first paper of this kind that provides new data from an Australian rural and regional perspective and adds value to the growing body of knowledge in the intersection of aged care and acute emergency care., (© 2023 National Rural Health Alliance Ltd.)

Background: Many palliative care patients attend emergency departments (EDs) in acute Hospital. However, very limited studies inform about their presentations and appropriateness., Objectives: This study explored the reasons and appropriateness of palliative care presentations in a regional Australian ED setting., Methods: A retrospective, single-centre observational study was conducted in a regional Australian hospital. All patients between January and December 2018 known to palliative care services presented to ED were included. Appropriateness of presentations was determined based on urgency of tests and treatments received, and practicability of obtaining these in a different setting., Results: A total of 35 patients made 85 presentations to the ED in 2018. The most common individual presenting complaints were shortness of breath (18.9%) followed by pain (14.1%), fever (11.8%), fall (8.2%), reduced oral intake or dehydration (8.2%), and bleeding (8.2%). The patients were brought by an ambulance in 56.5% presentations, and 63.5% presentations were admitted. About 93% presentations were referred by community healthcare professionals or required urgent investigation or management., Conclusions: This study found the majority of presentations were appropriate since their management could not be delivered at other primary care settings. This study adds value to the growing body of evidence and supports future multi-site longitudinal studies.

Infectious bursal disease (IBD) is a highly immunosuppressive and often fatal viral disease of young chickens. The causal agent IBD virus (IBDV) is an avian Birnavirus having two genome segments that have evolved independently and contributed to the emergence of many genotypes with different pathogenic profile. The present study aimed at genetic and pathogenic characterization of IBDVs from Bangladesh. We performed phylogenetic analysis of 15 IBDV isolates recovered from field outbreaks in chickens during 2020-2021 and compared the pathogenicity of three selected isolates belonging to different genotypes on experimental infection in chickens. Out of 15 isolates, one was the typical vvIBDV of genotype A3B2, 13 were reassortant vvIBDV of genotype A3B3 having very virulent-like segment A and early Australian-like segment B, and the remaining one isolate was a classical virulent IBDV of A1aB1 genotype. A few amino acid substitutions were observed between the genotypes in four putative antigenic sites on VP2. In a comparative pathogenicity study, the typical vvIBDV isolate BD-25(A3B2) appeared to be the most virulent with 100% morbidity and 90% mortality, followed by the segment-reassortant vvIBDV isolate BD-28(A3B3) with 50% morbidity and 30% mortality. However, the gross and histopathological lesions in the bursa of Fabricius were similar. The classical virulent isolate BD-26(A1aB1) did not cause any clinical disease. In conclusion, three genotypes of IBDV are co-circulating in poultry of Bangladesh and the typical vvIBDV of A3B2 genotype was more virulent than the reassortant vvIBDV of A3B3 genotype. Further studies are required to assess the country-wide distribution of IBDV of different genotypes and the efficacy of the currently available vaccines in protecting chickens against different genotypes of IBDV in Bangladesh., (Copyright © 2022 Elsevier Ltd. All rights reserved.)

Background: Rates of caesarean section (CS) delivery are increasing worldwide. CS delivery is often complicated by post-surgical infection, estimated to have ten times higher risk of infections than that of vaginal delivery. While widespread use of prophylactic antibiotics with CS has reduced post-CS infection, incidence may be reduced further by cleansing the vagina with betadine antiseptic wash prior to CS. However, reports are not consistent, and different antiseptics have been practised variably. Therefore, in order to ensure that the risks to the mother are as minimal as possible, it is important to determine whether vaginal irrigation with antiseptic wash reduces post-CS infection rate, and if so, which antiseptic is paramount., Methods: Women giving birth by elective or emergency CS will be assigned into either the intervention (1% povidone iodine (n = 125) or chlorhexidine (n = 125)) or the control (no-irrigation (n = 125)) group by using a block randomisation technique. Participants will receive vaginal cleansing with an intervention or no vaginal cleansing prior to CS. Follow-up will occur at day 14 and day 28 post-CS. A predeveloped questionnaire will be completed with patients' socio-demographic characteristics and required clinical and pregnancy-related information. All the fever, infection and readmission-related information will be completed from either the patient's or their record or at follow-up visits. Occurrence of post-CS infection, as measured by primary and secondary outcomes, will be compared between the groups., Discussion: The results of this study may provide important data to define the future uniform use of vaginal antiseptic wash immediately prior to CS and to determine the best antiseptic wash details in reducing post-operative infections or complications., Trial Registration: Australian New Zealand Clinical Trials Registry (ANZCTR) ACTRN12620000971932p . Registered on 28 September 2020., (© 2021. The Author(s).)

Cadmium (Cd) is a widespread environmental contaminant, and its increasing concentrations in rice poses significant risks to human health. Globally, rice is a staple food for millions of people, and consequently, effective strategies to reduce Cd accumulation in rice are needed. This study investigates the effect of soil pH (Soil 1: 4.6; Soil 2: 6.6) and iron (Fe) application (at 0, 1.0 and 2.0 g/kg) on Fe plaque formation, Cd sequestration in Fe plaques and Cd bioaccumulation in different parts of the rice plant for three different Cd-graded paddy soils (0, 1.0 and 3.0 mg/kg, respectively) using two Australian rice cultivars under glasshouse conditions. Results show that grain and straw yield declined as Cd toxicity increased, and the toxic effects of Cd were lower in the Quest cultivar than in the Langi cultivar. With applications of Cd at 1.0 mg/kg and 3.0 mg/kg, Cd concentrations in rice grown in Soil 1 were 1.09 mg/kg and 1.37 mg/kg, respectively, while those in rice grown in Soil 2 were 0.38 mg/kg and 0.52 mg/kg, respectively. Soil pH significantly affected the bioaccumulation of Cd in different parts of the rice plant. At both levels of Cd application, Cd concentration was highest in the root, followed by the stem, leaf, husk and grain. Cd was more concentrated in Fe plaques formed by the application of Fe than in rice plant tissues. The Quest cultivar had a higher ability to produce Fe plaques and a 1.3- and 1.4-times higher Cd concentration compared with the Langi cultivar in Soils 1 and 2, respectively., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2021 Elsevier B.V. All rights reserved.)

Understanding the transport behaviour of arsenic (As) from soils to humans is critical when undertaking human health risk assessment and contamination control. This research examined As bioaccessibility in different As fractions and particle size fractions of As-enriched mine soils using different extractions. Bioaccessibility of As ranged from 0.24% to 32% for Solubility Bioaccessibility Research Consortium (SBRC) and Physiologically Based Extraction Test (PBET) methods, with extractable As (using 0.43 M HNO 3 ) being 1.3-24.9%. The highest As bioaccessibility (19-32%) was consistently observed in the fine particle size fraction (< 53 µm) of all three extractions. Sequential extractions revealed that As fractions were mostly associated with crystalline (30-73%) and amorphous (9-59%) Fe/Al oxyhydroxides. The bioaccessibility of As in the gastric phase of SBRC and PBET methods highlighted a positive correlation (R 2 = 0.83-0.88, p < 0.01) with exchangeable, surface and amorphous- bound As fractions, while the intestinal phase showed a strong positive correlation (R 2 = 0.85-0.89, p < 0.01) with exchangeable and surface bound fractions. The study revealed that As bioaccessibility in soils can potentially be determined using the 0.43 M HNO 3 extraction procedure. Health risk assessment confirmed that there was a strong increase in chronic daily intake, hazard quotient and cancer risk, with a reduction in particle size., (Copyright © 2021 The Authors. Published by Elsevier Inc. All rights reserved.)

Background: Accurate prognostication is essential in caring for palliative patients. Various prognostication tools have been validated in many settings in the past few years. Biomarkers of inflammation (albumin and C-reactive protein) are combined to calculate the modified Glasgow prognostic score (mGPS), which has been found to be a simple prognostic tool in this population., Objective: This retrospective cohort study was to evaluate mGPS as a prognostication tool for cancer patients admitted to an acute hospital in regional Australia., Methods: Adult cancer patients admitted to an acute Australian regional hospital during 2017 who had albumin and C-reactive protein (CRP) tested were included. The mGPS was calculated based on their admission values and discharge values. Based on their score (0-2), groups were compared using univariate and multivariate Cox regression analysis for prognostication. Kaplan-Meier survival plots and median survival time from admission and discharge were constructed., Results: A total of 170 patient records were reviewed of which 95 had admission and discharge mGPS scores available for analysis. Of those, 86 had died at the time of data analysis. The median survival for admission mGPS 0, 1, 2 was 168,156 and 74 days. For discharge mGPS 0, 1, 2 medians were 168,119 and 70 days. On multi variate analysis admission mGPS 2 showed Hazard ratio of 2.29 (95% CI 1.16-4.56, p -0.02) and discharge mGPS 2 of 2.07 (95% CI 0.95-4.50, p value 0.07)., Conclusions: In this study, mGPS was able to differentiate cancer patients into various prognostic groups. Further studies in regional acute hospitals could validate this prospectively with a multi-center larger sample size.

This study examined the influence of soil physicochemical properties on the sorption, desorption and kinetics of beryllium (Be) uptake and release on soils from a legacy waste site in Australia. This information is needed to help explain the current distribution of Be at the site and evaluate potential future environmental risks. Sorption was determined by a batch study and key soil properties were assessed to explain Be retention. The soil was favourable for sorption of Be (up to 99%) due to organic content, negative surface charge, soil oxyhydroxides (Fe/Al/Mn-O/OH) and the porosity of the soil structure. Lesser sorption was observed in the presence of a background electrolyte (NaNO 3 ). Sorption closely followed pseudo second order kinetics and was best described by the Langmuir model. FTIR analysis suggested that chemisorption was the predominant mechanism of Be sorption. Desorption was very low and best described by the Freundlich model. The low desorption reflected the high K d (up to 6624 L/kg), and the presence of hysteresis suggested partially irreversible binding of Be with active surfaces of the soil matrix (minerals, SOM, oxyhydroxides of Fe/Al/Mn etc.). Intra-particle diffusion of Be and entrapment in the pores contribute to the irreversible binding. The sorption behaviour of Be helped to explain the relative immobility of Be at the site despite the significant quantities of Be disposed. Soil physicochemical properties were significant for Be sorption, through influencing both the uptake and desorption, and this demonstrates the implications of these measurements for evaluating potential future risks to the environment., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Crown Copyright © 2021. Published by Elsevier Ltd. All rights reserved.)

Infectious bursal disease virus (IBDV) of chickens is a birnavirus with a bi-segmented double-stranded RNA genome, the segments designated as A and B. We performed phylogenetic analysis using a 366-bp fragment of segment A (nt 785-1150) and a 508-bp fragment of segment B (nt 328-835) of IBDV. A total of 463 segment A and 434 segment B sequences from GenBank, including the sequences of eight recent Bangladeshi isolates, were used in the analysis. The analysis revealed eight genogroups of segment A under serotype 1, designated as A1 (classical), A2 (US antigenic variant), A3 (very virulent), A4 (dIBDV), A5 (atypical Mexican), A6 (atypical Italian), A7 (early Australian) and A8 (Australian variant), and a single genogroup under serotype 2, designated as A0. On the other hand, segment B could be categorized into five genogroups irrespective of serotype, these being B1 (classical-like), B2 (very virulent-like), B3 (early Australian-like), B4 (Polish & Tanzanian) and B5 (Nigerian). Segment B of serotype 2 strains clustered within genogroup B1. With the bi-segmented genome of IBDV, these differences would allow for a total of 45 possible assortments. Based on the combinations of segment A and segment B genogroups observed in 463 IBDV strains, a total of 15 genotypes could be recognized. Recent Bangladeshi IBDV strains, isolated in 2016, appeared to be segment reassortants having segment A of genogroup A3 (very virulent) and segment B of genogroup B3 (early Australian-like). An extended system of nomenclature of IBDV strains is proposed.

Background: Personality dimensions such as openness and agreeableness have been found to be associated with prejudice levels towards several minority groups. Yet these variables have been mostly ignored by existing research into attitudes towards people with intellectual disability (PWID), which has primarily focused on contact and demographic variables. The current study investigated the relationship between personality dimensions and attitudes toward PWID., Methods: An online survey was completed by 466 adult participants recruited through a variety of sources. The survey consisted of a well-validated attitude survey, the Big Five inventory, contact related and demographic questions., Results: The hypothesis that higher levels of the personality dimensions openness and agreeableness would be significantly associated with positive attitudes towards PWID was supported. However the effect was relatively weak and the strongest predicting factor of positive attitudes was increased quality of contact with PWID. More positive attitudes were also associated with females, more highly educated and younger participants., Conclusions: Results provide support for an integrated (including person and situational factors) theoretical approach to attitudes research in this field. Practically, results support programmes that stimulate and promote quality interactions between PWID and the wider community., (© 2015 MENCAP and International Association of the Scientific Study of Intellectual and Developmental Disabilities and John Wiley & Sons Ltd.)

Self-serving biases in attribution, while found with relative consistency in research with Western samples, have rarely been found in Japanese samples typically recruited for research. However, research conducted with Japanese participants to date has tended to use forced-choice and/or reactive paradigms, with school or university students, focusing mainly on academic performance or arbitrary and/or researcher-selected tasks. This archival study explored whether self-serving attributional biases would be shown in the real-life attributions for sporting performance made by elite Olympic athletes from Japan and Australia. Attributions (N = 216) were extracted from the sports pages of Japanese and Australian newspapers and rated by Australian judges for locus and controllability. It was hypothesized that Australian, but not Japanese, athletes would show self-serving biases such that they attributed wins to causes more internal and controllable than the causes to which they attributed losses. Contrary to predictions, self-serving biases were shown to at least some extent by athletes of both nationalities. Both Australian and Japanese men attributed wins to causes more internal than those to which they attributed losses. Women, however, attributed wins and losses to causes that did not differ significantly in terms of locus. All athletes tended to attribute wins to causes that were more controllable than the causes to which losses were attributed. Results are inconsistent with a large body of research suggesting that Japanese do not show self-serving biases in attribution, and are discussed in the light of differences in methodology, context, and participants that may have contributed to these effects.