1. Guidelines on the use of photodynamic therapy for nonmelanoma skin cancer: an international consensus. International Society for Photodynamic Therapy in Dermatology, 2005.
- Author
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Braathen, Lasse R., Szeimies, Rolf-Markus, Basset-Seguin, Nicole, Bissonnette, Robert, Foley, Peter, Pariser, David, Roelandts, Rik, Wennberg, Ann-Marie, Morton, Colin A., and International Society for Photodynamic Therapy in Dermatology
- Subjects
PHOTOCHEMOTHERAPY ,SKIN cancer ,CANCER treatment ,BASAL cell carcinoma ,THERAPEUTIC use of amino acids ,AMINO acids ,BASAL cell nevus syndrome ,CLINICAL trials ,COMPARATIVE studies ,KERATOSIS ,RESEARCH methodology ,MEDICAL cooperation ,PATIENT satisfaction ,PHOTOSENSITIVITY disorders ,RESEARCH ,SKIN diseases ,SKIN tumors ,SQUAMOUS cell carcinoma ,EVALUATION research ,DISEASE incidence ,BLIND experiment ,IMMUNOCOMPROMISED patients ,BOWEN'S disease ,PREVENTION - Abstract
Topical photodynamic therapy (PDT) is used to treat nonmelanoma skin cancers, such as actinic keratoses, Bowen''s disease, and basal cell carcinoma (superficial and nodular). This article presents up-to-date, practical, evidence-based recommendations on the use of topical PDT using 5-aminolevulinic acid or methyl aminolevulinate for the treatment (and prevention) of nonmelanoma skin cancers. A systematic literature review was conducted (using MEDLINE), and recommendations were made on the basis of the quality of evidence for efficacy, safety/tolerability, cosmetic outcome, and patient satisfaction/preference. Topical PDT is highly effective in the treatment of actinic keratoses, Bowen''s disease, superficial and thin nodular basal cell carcinomas, with cosmesis typically superior to that achieved with existing standard therapies. PDT may also be a means of preventing certain nonmelanoma skin cancers in immunosuppressed patients. [Copyright &y& Elsevier]
- Published
- 2007
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