1. Delayed-onset vocal cord palsy after thyroidectomy occurring despite normal initial post-operative endoscopy.
- Author
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Ren T, Manning S, Lee JC, and Serpell J
- Subjects
- Humans, Male, Female, Middle Aged, Aged, Time Factors, Adult, Endoscopy methods, Endoscopy adverse effects, Australia epidemiology, Thyroidectomy adverse effects, Vocal Cord Paralysis etiology, Vocal Cord Paralysis epidemiology, Recurrent Laryngeal Nerve Injuries etiology, Postoperative Complications epidemiology, Postoperative Complications etiology, Postoperative Complications diagnosis
- Abstract
Background: Recurrent laryngeal nerve (RLN) injury is a known complication of thyroidectomy. Most cases manifest immediately and are promptly recognized. Rarely, some patients experience delayed-onset vocal cord palsy. This can occur despite normal findings on intra-operative nerve monitoring and initial post-operative endoscopy. This can cause considerable distress for patients, and its incidence and prognosis should be recognized., Methodology: We report seven patients experiencing delayed-onset RLN palsy (RLNP) after thyroidectomy. All had normal findings on pre-operative flexible nasoendoscopy (FNE), intra-operative nerve monitoring at conclusion of surgery, and initial post-operative FNE. All diagnoses of RLNP were confirmed on endoscopy. Serial FNE examinations were performed to evaluate recovery., Results: Of seven patients (43% male, median age 65 years), the median timing of delayed-onset RLNP was 12 (range 9-35) days. RLNP was diagnosed on the unilateral side of surgery in six out of seven patients (86%). All received conservative management, including referral to voice therapy. All seven patients recovered vocal cord function after a median duration of 24 weeks (range 8-52 weeks), and six within ~6 months (28 weeks). The incidence of this complication was 0.1% (among 6607 thyroidectomies)., Conclusion: We report the first Australian series of delayed-onset vocal cord palsy after thyroidectomy. We explore its prognosis, discussing different pathophysiological mechanisms and the timeframe for recovery compared to most other RLN injuries. This may assist recognition of a rare complication, reassure patients, and facilitate early intervention to improve a patient's quality of life., (© 2024 The Author(s). ANZ Journal of Surgery published by John Wiley & Sons Australia, Ltd on behalf of Royal Australasian College of Surgeons.)
- Published
- 2024
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