1. Risk Factors for Nipah Virus Encephalitis in Bangladesh.
- Author
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Montgomery, Joel M., Hossain, Mohamed J., Gurley, E., Carroll, D. S., Croisier, A., Bertherat, E., Asgari, N., Formenty, P., Keeler, N., Comer, J., Bell, M. R., Akram, K., Molla, A. R., Zaman, K., Islam, Mohamed R., Wagoner, K., Mills, J. N., Rollin, P. E., Ksiazek, T. G., and Breiman, R. F.
- Subjects
NIPAH virus ,ENCEPHALITIS ,DISEASE risk factors ,PARAMYXOVIRUSES ,PATIENTS - Abstract
Nipah virus (NiV) is a paramyxovirus that causes severe encephalitis in humans. During January 2004, twelve patients with NiV encephalitis (NiVE) were identified in west-central Bangladesh. A case-control study was conducted to identify factors associated with NiV infection. NiVE patients from the outbreak were enrolled in a matched case-control study. Exact odds ratios (ORs) and 95% confidence intervals (CIs) were calculated by using a matched analysis. Climbing trees (83% of cases vs. 51% of controls, OR 8.2, 95% CI 1.25-8) and contact with another NiVE patient (67% of cases vs. 9% of controls, OR 21.4, 95% CI 2.78-966.1) were associated with infection. We did not identify an increased risk for NiV infection among persons who had contact with a potential intermediate host. Although we cannot rule out person-to-person transmission, case-patients were likely infected from contact with fruit bats or their secretions. [ABSTRACT FROM AUTHOR]
- Published
- 2008
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