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A recent study conducted in Beijing, China, explored the potential of using genetically modified macrophages to target and prevent atherosclerosis, a chronic inflammatory disease. The researchers engineered macrophages to overexpress interleukin-10 (IL-10), a protein known for its anti-inflammatory effects. These modified cells were then introduced into mice with atherosclerosis, resulting in a reduction in plaque formation and necrotic core. The study suggests that cell therapy using anti-inflammatory macrophages could be a promising strategy for treating atherosclerosis. [Extracted from the article]

New research from China Agricultural University explores the effects of advanced glycation end products (AGEs) on the intestinal barrier. AGEs are complex compounds found in processed foods and are known to impair the intestinal barrier, but the underlying mechanisms are not well understood. The study found that AGEs activate macrophages, which then suppress the expression of tight junctions (TJs) in intestinal cells, leading to impaired barrier function. These findings shed light on the mechanisms behind AGEs-induced intestinal barrier injury and related food safety risks. [Extracted from the article]

Researchers at Peking University in Beijing, China have discovered that extracellular vesicles (Comp-EVs) derived from compression-loaded cementoblasts can promote the tissue repair function of macrophages. These Comp-EVs enhance macrophage M2 polarization and the clearance of apoptotic cells, leading to the relief of cementum destruction and significant bone healing. The study also found that the secretion of Comp-EVs is reduced under compression, but overexpression of Rab35 can boost their production. This research suggests that Comp-EVs could be a potential therapeutic strategy for hard tissue repair and regeneration. [Extracted from the article]

A recent study conducted by Capital Medical University in Beijing, China, evaluated the efficacy and safety of recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) hydrogel in treating second- or third-degree burn wounds in children. The meta-analysis included eight reports and found that the experimental group, which received rhGM-CSF hydrogel, showed superior wound healing rates at day 7, day 14, and day 21 compared to the control group. The study concluded that rhGM-CSF hydrogel is significantly effective in improving wound healing rates and shortening healing time in children with burn wounds. [Extracted from the article]

A recent study conducted by the Chinese Academy of Sciences explores the use of decellularized amnion membrane (DAM) as a biomaterial implant. The study found that DAM can regulate macrophage-driven inflammatory responses and promote tissue regeneration. In vitro experiments showed that DAM inhibits M1 polarization in macrophages and promotes M2 polarization. In a rat model, DAM inhibited inflammation and fibrous capsule formation while facilitating M2 macrophage polarization. These findings suggest that DAM has immunomodulatory properties and could be a promising material for tissue repair implants. [Extracted from the article]

A recent study conducted by researchers at Peking University First Hospital in Beijing, China, has investigated the role of a S1P receptor modulator called FTY720 in experimental autoimmune vasculitis (EAV). The study found that FTY720 treatment significantly reduced renal injury and pulmonary hemorrhage in EAV. The researchers also discovered that FTY720 upregulated fatty acid oxidation (FAO) through the PPAR alpha-CPT1a pathway in neutrophils, offering potential immunometabolic targets for the treatment of ANCA-associated vasculitis (AAV). This research provides valuable insights into the pathogenesis and potential treatment options for AAV. [Extracted from the article]

A study conducted by researchers at Capital Medical University in Beijing, China, has found that liraglutide, a medication used to treat type 2 diabetes, may enhance the effectiveness of checkpoint blockade therapy in lung and liver cancers. The researchers discovered that liraglutide reduced the presence of neutrophil extracellular traps (NETs) in tumor-bearing mice, which improved the anti-tumoral efficiency of programmed cell death-1 (PD-1) inhibition. The combination therapy also resulted in long-term antitumor CD8+ T cell responses. These findings suggest that liraglutide has the potential to be used as a complementary treatment for lung and liver cancers. [Extracted from the article]

A study conducted at Beijing Sport University in China explored the potential mechanism of action of Shakuyakukanzoto (SKT) in improving ulcerative colitis (UC) in mice. The researchers found that SKT can alleviate colon damage caused by UC and inhibit the polarization of macrophages to the M1 phenotype. They also identified a correlation between glycolysis, oxidative phosphorylation, and the gene NDUFS1 with a reduced risk of UC. These findings provide insights into the therapeutic mechanism of SKT for UC and offer a new theoretical basis for clinical application. [Extracted from the article]

A study conducted by researchers at Capital Medical University in Beijing, China, examined the role of the ORAI1 calcium channel in macrophages and its impact on pancreatic tissue damage in experimental acute pancreatitis (AP). The study found that myeloid-specific deletion of ORAI1 had minimal effect on store-operated Ca2+ entry (SOCE) in macrophages and did not significantly affect pancreatic tissue damage or infiltration of neutrophils and macrophages in two models of AP. Additionally, myeloid-specific ORAI1 deletion did not influence overall survival rate or organ damage in a model of sepsis. These findings suggest that ORAI1 may not be a predominant SOCE channel in macrophages and may play a limited role in mediating pancreatic tissue damage in AP. [Extracted from the article]

A recent study conducted by the Chinese Academy of Medical Sciences has identified a novel homozygous ADK out-of-frame deletion in a Chinese patient with adenosine kinase deficiency. This deficiency is a rare genetic disorder that can cause various symptoms, including neurological disorders, hepatic impairment, and developmental delay. The patient in this study exhibited rare phenotypes of sepsis, metabolite disruption, and neutrophil dysfunction. The findings of this research contribute to a better understanding of the genetic spectrum and pathogenic mechanisms of adenosine kinase deficiency. [Extracted from the article]

A recent study conducted at Peking Union Medical College in Beijing, China, explored the potential prognostic value of the Neutrophil-to-Lymphocyte Ratio (NLR) in ovarian cancer. The study involved a systematic review and meta-analysis of 20 studies, which included patients of various ethnicities, ages, and sample sizes. The findings indicated that a high NLR was associated with poorer overall survival and progression-free survival in ovarian cancer patients. However, the researchers noted the presence of heterogeneity and the need for further investigation. This study highlights the potential of NLR as a cost-effective prognostic biomarker for ovarian cancer. [Extracted from the article]

A recent study conducted at China-Japan Friendship Hospital in Beijing, China, explored the role of microRNA-133a-3p (miR-133a-3p) in sepsis-induced acute respiratory distress syndrome (ARDS). The researchers found that upregulation of miR-133a-3p in alveolar macrophages was associated with increased inflammatory cytokines and histopathologic changes. However, down-regulation of miR-133a-3p resulted in a protective effect on lung tissue by up-regulating the levels of SIRT1, suppressing the inflammatory response, and inhibiting cellular apoptosis. These findings suggest that targeting miR-133a-3p and SIRT1 could be a potential therapeutic strategy for ARDS. [Extracted from the article]

A study conducted at Peking University People's Hospital in Beijing, China, has found that androgen deprivation therapy (ADT) for prostate cancer is associated with an increased risk of cardiovascular diseases. The researchers focused on the role of follicle-stimulating hormone (FSH) in ADT-associated atherosclerosis and found that FSH elevation exaggerated endothelial inflammation and promoted monocyte-endothelial adhesion, leading to atherosclerosis. The study concluded that FSH is responsible for ADT-associated atherosclerosis by exacerbating endothelial inflammation and promoting monocyte-endothelial adhesion. This research provides new insights into the mechanisms behind ADT-associated cardiovascular diseases. [Extracted from the article]

A recent study conducted by researchers at Capital Medical University in Beijing, China, investigated the pharmacological mechanism of Moluodan (MLD), a traditional Chinese medicine used to treat chronic gastritis. The study found that while MLD exhibited hemostatic effects, it unexpectedly exacerbated intestinal inflammation in a mouse model. MLD promoted the polarization of M1 macrophages and increased the expression of proinflammatory cytokines through the AKT/NF-kappa B pathway. The researchers concluded that MLD may not be suitable for colitis, particularly during the acute inflammation stage. [Extracted from the article]

A recent study conducted by Capital Medical University in Beijing, China, analyzed the risk factors for acute asthma attacks complicated by respiratory failure in children. The study involved 225 participants, with 18.7% diagnosed with respiratory failure. The research found that younger age, male gender, emergency hospitalization, ICU treatment, severe to critical attack, dyspnea, and allergy history were associated with respiratory failure. Additionally, having a history of allergies and a higher neutrophil count were identified as risk factors. The study suggests that timely intervention based on these factors can optimize the treatment of asthma in children. [Extracted from the article]

A recent study conducted at Peking Union Medical College Hospital in Beijing, China, explored the effects of radiofrequency ablation (RFA) on the immune response in patients with recurrent hepatocellular carcinoma (HCC). The researchers found that RFA treatment led to an increase in monocytes and a decrease in T cell subpopulations. The expression of certain genes involved in the cytotoxic function of T cells was also down-regulated following RFA. Additionally, the study observed elevated secretion of VEGF in various immune cells, which contributes to an immunosuppressive microenvironment. These findings suggest that while RFA enhances the antigen-presenting capacity of monocytes, it also inhibits the anti-cancer immune response. [Extracted from the article]

A report from China Agricultural University in Beijing, People's Republic of China, discusses the role of macrophage polarization in the failure of classical swine fever (CSF) vaccines due to porcine reproductive and respiratory syndrome virus (PRRSV) infection. The study found that PRRSV infection induced macrophages to polarize to M1, which inhibited the replication of CSFV-C, while CSFV-C infection induced macrophages to polarize to M2. Chinese medicine and interferon-g and lipopolysaccharide co-stimulation were found to affect macrophage polarization and replication of CSFV-C. The research provides a basis for developing new strategies to improve the immune effect of CSFV-C based on macrophage polarization. [Extracted from the article]

Researchers from Peking University Third Hospital in Beijing, China have conducted a study on the role of Lymphocyte Cytosolic Protein 1 (LCP1) in ischemic brain injury and immune cell signaling and metabolism. The study found that knocking down LCP1 in monocyte-derived macrophages (MoDMs) led to a reduction in neuroinflammation and improved neurological behaviors in mice. The researchers also discovered that LCP1 plays a role in regulating mitochondrial function and fatty acid uptake. These findings provide valuable insights into potential therapeutic strategies for attenuating neuroinflammation and lymphopenia in ischemic stroke. [Extracted from the article]

A recent study conducted by researchers at Capital Medical University in Beijing, China, focused on the genes involved in oxidative stress production and clearance in macrophages infected with Mycobacterium tuberculosis (MTB). The researchers established a macrophage model infected with MTB and analyzed the production of reactive oxygen species (ROS) using flow cytometry. They identified 1,613 differentially expressed genes associated with ROS, with six genes showing significant changes in expression after MTB infection. The study suggests that these genes may be related to ROS and could serve as potential targets for antituberculosis treatments. [Extracted from the article]

A recent study from Beijing, China, explores the role of tissue-resident macrophages (TRMs) in sepsis-associated organ dysfunction (SAOD). Sepsis is a life-threatening condition characterized by organ dysfunction, and TRMs are a type of macrophage that play a crucial role in the body's defense against sepsis. The study suggests that modulating TRMs in different organs could potentially attenuate sepsis, septic shock, and SAOD. The research provides a summary of the pathophysiological mechanisms of TRMs in various organs involved in the development and progression of sepsis. [Extracted from the article]

A recent study conducted at Xuanwu Hospital of Capital Medical University in Beijing, China, explored the role of long noncoding RNAs (lncRNAs) and mRNAs in intracranial atherosclerotic stenosis (ICAS) from the perspective of neutrophils. The study involved 19 patients with ICAS and 15 healthy controls, and the expression profiles of lncRNAs and mRNAs in neutrophils were analyzed. Four lncRNAs were identified and validated, and ceRNA and lncRNA-RNA binding protein (RBP)-mRNA networks were constructed. The study provides insights into the pathogenic mechanisms and potential drug design for ICAS. [Extracted from the article]

A recent study conducted by researchers at the Medical School of Chinese People's Liberation Army (PLA) in Beijing, China, has investigated the use of FK506 therapy in reducing immune rejection in organ transplantation. The study found that FK506, an immunosuppressive drug commonly used in organ transplantation, can enhance DNA methylation, which leads to a reduction in the formation of neutrophil extracellular traps (NETs). NETs, while playing a role in antimicrobial defense, can also contribute to inflammation and tissue damage when overproduced. This discovery provides valuable insights for clinical research and organ preservation strategies. [Extracted from the article]

A recent study conducted by researchers at Peking University in Beijing, China, has shed light on the role of vimentin, an intermediate filament protein, in regulating the nuclear segmentation of granulocytes, particularly neutrophils. The researchers used cryo-electron tomography to examine the nuclei of mouse neutrophils and found that vimentin is responsible for the perinuclear structures observed in these cells. Genetic deletion of vimentin resulted in a reduction in the number of nuclear lobes in neutrophils and eosinophils, similar to the Pelger-Huet anomaly. This study provides new insights into the mechanisms underlying the distinct morphological features of granulocytes. [Extracted from the article]

A new report from Fuwai Hospital in Beijing, China presents fresh data on heart failure and coronary atherosclerosis. The researchers used single-cell RNA sequencing to study the perivascular adipose tissue (PVAT) surrounding the coronary arteries in patients with end-stage heart failure. They identified several cellular subpopulations, including SPP1(+) macrophages, that were accumulated in PVAT surrounding atherosclerotic coronary arteries. These macrophages promoted the migration and proliferation of fibroadipogenic progenitor cells, leading to increased fibrosis in the coronary PVAT. The findings suggest that SPP1(+) macrophages may play a role in the progression of coronary atherosclerosis. [Extracted from the article]

A new study conducted by researchers at Capital Medical University in Beijing, China, explores the role of macrophage pyroptosis in silica-induced pulmonary fibrosis. The study found that silica exposure increased the expression of pyroptosis-related indicators in macrophages, which in turn promoted the upregulation of fibrosis markers in lung fibroblasts. However, when macrophage pyroptosis was inhibited, the upregulation of fibrosis markers was alleviated. These findings suggest that inhibiting macrophage pyroptosis could be a potential clinical strategy for alleviating silicosis. [Extracted from the article]

A recent study conducted by researchers at Peking University in Beijing, China, has investigated the role of neutrophil extracellular traps (NETs) in the metastasis of colorectal cancer (CRC). The study found that CRC patients have an increased capacity for NETs formation, which positively correlates with the progression of the disease. The researchers identified the protein integrin a5b1 as a key player in the interaction between NETs and tumor cells, promoting adhesion, proliferation, and migration. By targeting NADPH oxidase and integrin a5b1, the researchers were able to effectively suppress tumor progression in vivo. This study provides valuable insights into the mechanism of NETs-mediated metastasis and suggests a potential combination therapy for CRC. [Extracted from the article]

A recent report from Peking University People's Hospital in Beijing, China, explores the role of neutrophil peptide 1 in peripheral nerve regeneration. The study investigates the relationship between neutrophil peptide 1 and macrophages in peripheral nerve crush injury. The findings suggest that neutrophil peptide 1 promotes the proliferation, migration, and phagocytosis of macrophages, leading to enhanced axonal debris clearance during Wallerian degeneration. This research provides insight into the mechanisms by which neutrophil peptide 1 enhances peripheral nerve regeneration. [Extracted from the article]

A recent report from Beijing Hospital highlights the role of neutrophil dysregulation in the development of rheumatic diseases and conditions (RMD). The exact mechanisms of RMD are still largely unknown, but increasing evidence suggests that neutrophil dysfunction plays a pathogenic role. The review discusses recent advancements in understanding neutrophil dysregulation and explores strategies for targeting pathways associated with it as potential treatments for RMD. Neutrophil extracellular traps (NETs) are a specific aspect of neutrophil dysregulation that have been found to contribute to chronic pulmonary inflammation and fibrosis. The research concludes that a deeper understanding of the mechanisms underlying neutrophil dysregulation could lead to more precise and effective targeting strategies for RMD. [Extracted from the article]

A recent study conducted at Peking University Third Hospital in Beijing, China, explored the use of PEG-modification recombinant human granulocyte colony stimulating factor (PEG-rhG-CSF) in patients undergoing autologous peripheral blood stem cell transplantation (PBSCT) for lymphoma. The study compared the efficacy and safety of PEG-rhG-CSF with rhG-CSF in terms of hematologic recovery time, incidence of infectious complications, and toxicity. The results showed that PEG-rhG-CSF marginally accelerated neutrophil engraftment by one day compared to rhG-CSF, without increasing the risk of complications. Administering PEG-rhG-CSF on day 1 after transplantation was found to achieve faster hematologic recovery and lower infectious complications. [Extracted from the article]

A recent report from researchers at the Medical School of Chinese People's Liberation Army (PLA) in Beijing, China, explores the role of macrophages in the progression of osteoarthritis (OA). The study highlights the importance of macrophage polarization, specifically the imbalance between pro-inflammatory (M1) and anti-inflammatory/tissue-repairing (M2) phenotypes, in the severity of OA. The researchers suggest that targeting macrophage polarization could be a promising therapeutic approach for OA. The report also reviews potential therapies, including intra-articular cell/derivates-based therapy and non-invasive interventions such as photobiomodulation therapy. [Extracted from the article]

Researchers from Peking University in Beijing, China have developed a new approach to treating early atherosclerosis, a common cause of cardiovascular diseases. They created a hybrid cell by fusing M2 macrophages with thylakoid (TK) membranes, which showed promising results in eliminating atherosclerotic plaques without significant side effects. The TK-M2 cells accumulated in the plaques and relieved cholesterol accumulation and inflammation, while the TK membranes induced apoptosis of foam cells under ultrasound activation. This study provides a potential new avenue for the treatment of atherosclerosis. [Extracted from the article]

Keywords: Beijing; People's Republic of China; Asia; Blood Cells; Granulocytes; Health and Medicine; Hemic and Immune Systems; Immunology; Immunopathology; Inflammation; Mouth Diseases and Conditions; Neutrophils; Periodontal Diseases and Conditions; Periodontitis; Phagocytes EN Beijing People's Republic of China Asia Blood Cells Granulocytes Health and Medicine Hemic and Immune Systems Immunology Immunopathology Inflammation Mouth Diseases and Conditions Neutrophils Periodontal Diseases and Conditions Periodontitis Phagocytes 1466 1466 1 11/06/23 20231110 NES 231110 2023 NOV 10 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Week -- Fresh data on Periodontal Diseases and Conditions - Periodontitis are presented in a new report. In human and mouse periodontitis, the waning of inflammation is correlated with OTUD1 upregulation, whereas severe periodontitis is induced when neutrophil-intrinsic OTUD1 is depleted. [Extracted from the article]

Keywords: Beijing; People's Republic of China; Asia; Biological Factors; Blood Cells; Colony Stimulating Factors; Cytokines; Dialysis; Erythropoietin; Granulocytes; Health and Medicine; Hemic and Immune Systems; Hemodialysis; Immunology; Intercellular Signaling Peptides and Proteins; Lymphocytes; Mononuclear Leukocytes; Neutrophils; Peptides; Phagocytes; Proteins EN Beijing People's Republic of China Asia Biological Factors Blood Cells Colony Stimulating Factors Cytokines Dialysis Erythropoietin Granulocytes Health and Medicine Hemic and Immune Systems Hemodialysis Immunology Intercellular Signaling Peptides and Proteins Lymphocytes Mononuclear Leukocytes Neutrophils Peptides Phagocytes Proteins 3607 3607 1 10/30/23 20231103 NES 231103 2023 NOV 3 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Week -- Current study results on Dialysis - Hemodialysis have been published. According to the news editors, the research concluded: "A higher NLR level was shown to be a cheaper method to predict worse EPO responsiveness in HD patients." This study aims to investigate the relationship between NLR and PLR and EPO responsiveness in maintenance HD patients. [Extracted from the article]

Keywords: Chronic Periodontitis; Connective Tissue Cells; Cytokines; Genetics; Health and Medicine; Immunology; Intercellular Signaling Peptides and Proteins; Interferons; Macrophages; Mononuclear Phagocyte System; Mouth Diseases and Conditions; Myeloid Cells; Periodontal Diseases and Conditions; Periodontitis; Phagocytes; Proteomics; Stomatognathic Diseases and Conditions EN Chronic Periodontitis Connective Tissue Cells Cytokines Genetics Health and Medicine Immunology Intercellular Signaling Peptides and Proteins Interferons Macrophages Mononuclear Phagocyte System Mouth Diseases and Conditions Myeloid Cells Periodontal Diseases and Conditions Periodontitis Phagocytes Proteomics Stomatognathic Diseases and Conditions 5768 5768 1 10/24/23 20231027 NES 231027 2023 OCT 27 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Week -- Current study results on chronic periodontitis have been published. It is also found that macrophage phenotype transitions in periodontitis involve the release of higher levels of IFNb, ISG15, and IL10 by the anti-inflammatory M2 macrophage phenotype compared to the pro-inflammatory M1 phenotype and myeloid-derived suppressor cells (MDSCs).". [Extracted from the article]

Keywords: Beijing; People's Republic of China; Asia; Antineoplastic Monoclonal Antibodies; Antineoplastics; Bevacizumab Therapy; Biomarkers; Biosimilars; Cancer; Carcinomas; Diagnostics and Screening; Drugs and Therapies; Health and Medicine; Immunologic Agents; Immunology; Liver Cancer; Macrophages; Monoclonal Antibodies; Mononuclear Phagocyte System; Oncology; Phagocytes; Pharmaceuticals; Tyrosine Kinase Inhibitors; VEGF - VEGFR Inhibitors; VEGFR Inhibitors EN Beijing People's Republic of China Asia Antineoplastic Monoclonal Antibodies Antineoplastics Bevacizumab Therapy Biomarkers Biosimilars Cancer Carcinomas Diagnostics and Screening Drugs and Therapies Health and Medicine Immunologic Agents Immunology Liver Cancer Macrophages Monoclonal Antibodies Mononuclear Phagocyte System Oncology Phagocytes Pharmaceuticals Tyrosine Kinase Inhibitors VEGF - VEGFR Inhibitors VEGFR Inhibitors 821 821 1 10/16/23 20231017 NES 231017 2023 OCT 17 (NewsRx) -- By a News Reporter-Staff News Editor at Immunotherapy Weekly -- Researchers detail new data in Oncology - Liver Cancer. For more information on this research see: Serum Concentration of Cd137 and Tumor Infiltration By M1 Macrophages Predict the Response To Sintilimab Plus Bevacizumab Biosimilar In Advanced Hepatocellular Carcinoma Patients. [Extracted from the article]

Previous basic research on acupuncture analgesia has focused mostly on the nervous system, with few studies addressing the immune system as a potential pathway of acupuncture analgesia." Keywords: Beijing; People's Republic of China; Asia; Acupuncture Analgesia; Acupuncture Therapy; Blood Cells; Complementary and Alternative Medicine; Electric Stimulation Therapy; Electroacupuncture; Endorphins; Granulocytes; Health and Medicine; Hemic and Immune Systems; Immunology; Nerve Tissue Proteins; Neuropeptides; Neutrophils; Opioid Peptides; Peptide Hormones; Peptide Proteins; Phagocytes; Pituitary Hormones; Pro-Opiomelanocortin; beta-Endorphin EN Beijing People's Republic of China Asia Acupuncture Analgesia Acupuncture Therapy Blood Cells Complementary and Alternative Medicine Electric Stimulation Therapy Electroacupuncture Endorphins Granulocytes Health and Medicine Hemic and Immune Systems Immunology Nerve Tissue Proteins Neuropeptides Neutrophils Opioid Peptides Peptide Hormones Peptide Proteins Phagocytes Pituitary Hormones Pro-Opiomelanocortin beta-Endorphin 1032 1032 1 10/09/23 20231013 NES 231013 2023 OCT 9 (NewsRx) -- By a News Reporter-Staff News Editor at Pain & Central Nervous System Week -- A new study on Complementary and Alternative Medicine - Acupuncture Therapy is now available. [Extracted from the article]

Keywords: Beijing; People's Republic of China; Asia; Alveolar Macrophages; Animal Diseases and Conditions; Arterivirus Infections; Connective Tissue Cells; Immunology; Macrophages; Myeloid Cells; Nidovirales Infections; Phagocytes; Porcine Reproductive and Respiratory Syndrome; RNA Viruses; Swine Diseases and Conditions; Virology; Viruses EN Beijing People's Republic of China Asia Alveolar Macrophages Animal Diseases and Conditions Arterivirus Infections Connective Tissue Cells Immunology Macrophages Myeloid Cells Nidovirales Infections Phagocytes Porcine Reproductive and Respiratory Syndrome RNA Viruses Swine Diseases and Conditions Virology Viruses 14 14 1 10/09/23 20231009 NES 231009 2023 OCT 9 (NewsRx) -- By a News Reporter-Staff News Editor at Veterinary Week -- New research on Animal Diseases and Conditions - Porcine Reproductive and Respiratory Syndrome is the subject of a report. Beijing, People's Republic of China, Asia, Alveolar Macrophages, Animal Diseases and Conditions, Arterivirus Infections, Connective Tissue Cells, Immunology, Macrophages, Myeloid Cells, Nidovirales Infections, Phagocytes, Porcine Reproductive and Respiratory Syndrome, RNA Viruses, Swine Diseases and Conditions, Virology, Viruses. [Extracted from the article]

Keywords: Beijing; People's Republic of China; Asia; Connective Tissue Cells; Cranial Nerve Diseases and Conditions; Cranial Nerve Injury; Craniocerebral Trauma; Cytoplasmic Structures; Exosomes; Facial Diseases and Conditions; Facial Nerve Diseases and Conditions; Facial Nerve Injury; Health and Medicine; Immunology; Inflammation; Macrophages; Mesenchymal Stem Cells; Mononuclear Phagocyte System; Myeloid Cells; Nervous System Diseases and Conditions; Organelles; Phagocytes; Stem Cell Research; Transport Vesicles EN Beijing People's Republic of China Asia Connective Tissue Cells Cranial Nerve Diseases and Conditions Cranial Nerve Injury Craniocerebral Trauma Cytoplasmic Structures Exosomes Facial Diseases and Conditions Facial Nerve Diseases and Conditions Facial Nerve Injury Health and Medicine Immunology Inflammation Macrophages Mesenchymal Stem Cells Mononuclear Phagocyte System Myeloid Cells Nervous System Diseases and Conditions Organelles Phagocytes Stem Cell Research Transport Vesicles 586 586 1 09/25/23 20230928 NES 230928 2023 SEP 25 (NewsRx) -- By a News Reporter-Staff News Editor at Stem Cell Week -- Current study results on Facial Diseases and Conditions - Facial Nerve Injury have been published. Beijing, People's Republic of China, Asia, Connective Tissue Cells, Cranial Nerve Diseases and Conditions, Cranial Nerve Injury, Craniocerebral Trauma, Cytoplasmic Structures, Exosomes, Facial Diseases and Conditions, Facial Nerve Diseases and Conditions, Facial Nerve Injury, Health and Medicine, Immunology, Inflammation, Macrophages, Mesenchymal Stem Cells, Mononuclear Phagocyte System, Myeloid Cells, Nervous System Diseases and Conditions, Organelles, Phagocytes, Stem Cell Research, Transport Vesicles. [Extracted from the article]

Keywords: Beijing; People's Republic of China; Asia; Emerging Technologies; Health and Medicine; Immunology; Macrophages; Mononuclear Phagocyte System; Nanosheets; Nanotechnology; Phagocytes EN Beijing People's Republic of China Asia Emerging Technologies Health and Medicine Immunology Macrophages Mononuclear Phagocyte System Nanosheets Nanotechnology Phagocytes 239 239 1 09/25/23 20230928 NES 230928 2023 SEP 28 (NewsRx) -- By a News Reporter-Staff News Editor at Blood Weekly -- Current study results on Nanotechnology - Nanosheets have been published. The mild thermal stimulation produced by photothermal conversion of Ti3C2Tx under NIR irradiation promoted macrophage M2 polarization in vitro. [Extracted from the article]

Acute liver injury was associated with elevated macrophage migration inhibitory factor (MIF) levels in damaged hepatocytes." Keywords: Beijing; People's Republic of China; Asia; Biological Factors; Connective Tissue Cells; Cytokines; Eicosanoids; Gastroenterology; Health and Medicine; Hepatocytes; Immunology; Intercellular Signaling Peptides and Proteins; Leukocyte Migration-Inhibitory Factors; Lymphokines; Macrophage Migration-Inhibitory Factors; Macrophages; Mononuclear Phagocyte System; Myeloid Cells; Peptides; Phagocytes; Prostaglandins; Proteins EN Beijing People's Republic of China Asia Biological Factors Connective Tissue Cells Cytokines Eicosanoids Gastroenterology Health and Medicine Hepatocytes Immunology Intercellular Signaling Peptides and Proteins Leukocyte Migration-Inhibitory Factors Lymphokines Macrophage Migration-Inhibitory Factors Macrophages Mononuclear Phagocyte System Myeloid Cells Peptides Phagocytes Prostaglandins Proteins 271 271 1 08/07/23 20230807 NES 230807 2023 AUG 7 (NewsRx) -- By a News Reporter-Staff News Editor at Gastroenterology Week -- Research findings on Intercellular Signaling Peptides and Proteins - Lymphokines are discussed in a new report. [Extracted from the article]

Cancer immunotherapy focusses on activating and strengthening immune response or eliminating suppression from tumor cells in each step of the cancer-immunity cycle; thus, it strengthens the body's immunity against tumors. Cancer, Connective Tissue Cells, Drug Delivery, Drug Delivery Systems, Drugs and Therapies, Health and Medicine, Immunology, Immunotherapy, Macrophages, Mononuclear Phagocyte System, Myeloid Cells, Oncology, Phagocytes Keywords: Cancer; Connective Tissue Cells; Drug Delivery; Drug Delivery Systems; Drugs and Therapies; Health and Medicine; Immunology; Immunotherapy; Macrophages; Mononuclear Phagocyte System; Myeloid Cells; Oncology; Phagocytes EN Cancer Connective Tissue Cells Drug Delivery Drug Delivery Systems Drugs and Therapies Health and Medicine Immunology Immunotherapy Macrophages Mononuclear Phagocyte System Myeloid Cells Oncology Phagocytes 515 515 1 07/17/23 20230720 NES 230720 2023 JUL 18 (NewsRx) -- By a News Reporter-Staff News Editor at Immunotherapy Weekly -- Investigators discuss new findings in cancer. [Extracted from the article]

Keywords: Beijing; People's Republic of China; Asia; Alcohols; Bioengineering; Biomedical Engineering; Biomedicine; Biotechnology; Cardiology; Cellular Structures; Connective Tissue Cells; Extracellular Matrix; Extracellular Space; Glycopeptides; Health and Medicine; Heart Attack; Heart Disease; Heart Disorders and Diseases; Hydrogel; Immunology; Inflammation; Macrophages; Mononuclear Phagocyte System; Myeloid Cells; Myocardial Infarction; Myocardial Ischemia; Organic Chemicals; Peptides and Proteins; Phagocytes; Polyethylene Glycols; Tissue Engineering; Tissue Regeneration; Vascular Diseases and Conditions EN Beijing People's Republic of China Asia Alcohols Bioengineering Biomedical Engineering Biomedicine Biotechnology Cardiology Cellular Structures Connective Tissue Cells Extracellular Matrix Extracellular Space Glycopeptides Health and Medicine Heart Attack Heart Disease Heart Disorders and Diseases Hydrogel Immunology Inflammation Macrophages Mononuclear Phagocyte System Myeloid Cells Myocardial Infarction Myocardial Ischemia Organic Chemicals Peptides and Proteins Phagocytes Polyethylene Glycols Tissue Engineering Tissue Regeneration Vascular Diseases and Conditions 188 188 1 07/17/23 20230717 NES 230717 2023 JUL 20 (NewsRx) -- By a News Reporter-Staff News Editor at Cardiovascular Week -- Current study results on Biomedical Engineering - Tissue Engineering have been published. Our news editors obtained a quote from the research from National Center for Cardiovascular Diseases, "Herein, a hybrid hydrogel coassembled by acellular cardiac extracellular matrix (ECM) and immunomodulatory glycopeptide is developed for endogenous tissue regeneration after MI. [Extracted from the article]

Keywords: Beijing; People's Republic of China; Asia; Cancer; Connective Tissue Cells; Cytometry; Cytoplasmic Structures; Exosomes; Health and Medicine; Immunology; Macrophages; Mononuclear Phagocyte System; Myeloid Cells; Oncology; Organelles; Phagocytes; Thyroid Cancer; Thyroid Neoplasms; Transport Vesicles EN Beijing People's Republic of China Asia Cancer Connective Tissue Cells Cytometry Cytoplasmic Structures Exosomes Health and Medicine Immunology Macrophages Mononuclear Phagocyte System Myeloid Cells Oncology Organelles Phagocytes Thyroid Cancer Thyroid Neoplasms Transport Vesicles 671 671 1 07/17/23 20230718 NES 230718 2023 JUL 18 (NewsRx) -- By a News Reporter-Staff News Editor at Cancer Weekly -- Investigators publish new report on Oncology - Thyroid Cancer. To examine the effect of TC cells on macrophage polarization, macrophages were co-incubated with SW1736 cells and then exosome secretion inhibitor (GW4869) was added. [Extracted from the article]

That was, SiNPs caused ROS accumulation in macrophages, resulting in the deactivation of PPAR7, nuclear translocation of NF-xB, ultimately contributing to macrophage pheno-type shift toward M1 and foam cell transformation. Keywords: Beijing; People's Republic of China; Asia; Connective Tissue Cells; Emerging Technologies; Foam Cells; Health and Medicine; Hemic and Immune Systems; Immunology; Macrophages; Mononuclear Phagocyte System; Myeloid Cells; Nanoparticles; Nanotechnology; Phagocytes; Silicon Nanocrystals EN Beijing People's Republic of China Asia Connective Tissue Cells Emerging Technologies Foam Cells Health and Medicine Hemic and Immune Systems Immunology Macrophages Mononuclear Phagocyte System Myeloid Cells Nanoparticles Nanotechnology Phagocytes Silicon Nanocrystals 821 821 1 07/10/23 20230714 NES 230714 2023 JUL 14 (NewsRx) -- By a News Reporter-Staff News Editor at Genomics & Genetics Weekly -- New research on Nanotechnology - Nanoparticles is the subject of a report. [Extracted from the article]

Keywords: Beijing; People's Republic of China; Asia; Blood Cells; Bone Marrow Cells; Cancer; Cell Research; Health and Medicine; Hemic and Immune Systems; Immunology; Monocytes; Mononuclear Leukocytes; Mononuclear Phagocyte System; Myeloid Cells; Oncology; Phagocytes EN Beijing People's Republic of China Asia Blood Cells Bone Marrow Cells Cancer Cell Research Health and Medicine Hemic and Immune Systems Immunology Monocytes Mononuclear Leukocytes Mononuclear Phagocyte System Myeloid Cells Oncology Phagocytes 373 373 1 05/29/23 20230530 NES 230530 2023 MAY 30 (NewsRx) -- By a News Reporter-Staff News Editor at Cancer Weekly -- New research on Cancer is the subject of a report. This is due to monocyte education by tumor cells, in which tumoral VEGF-A upregulates BEST1 expression on monocytes through the MEK-ERK-ELK1 pathway. [Extracted from the article]

On the contrary, the interaction between immune cells infiltrated by tumor microenvironment and tumor cells can promote and maintain the tumor cell sternness and has become a focus of studies because of its strong application prospects. "Tumor microenvironment factors can promote the tumor cell sternness to rely on the interaction between cells, and the tumor microenvironment is consisted of stromal infiltrating immune cells and other cells. In view of the fact that tumor-associated macrophages promote tumor progression, clearing tumor-associated macrophages and promoting the transformation of tumor-associated macrophages into immune activation have become potential methods for tumor treatment.". [Extracted from the article]

Keywords: Beijing; People's Republic of China; Asia; Agranulocytosis; Autoimmune Diseases and Conditions; Autoimmunity; Blood Cells; Bone Marrow Cells; Drugs and Therapies; Granulocytes; Health and Medicine; Hematologic Diseases and Conditions; Hematology; Hematopoietic Stem Cells; Hemic and Immune Systems; Hemic and Lymphatic Diseases and Conditions; Immune System Diseases and Conditions; Immunology; Leukocyte Diseases and Conditions; Leukocyte Disorders; Leukopenia; Neutropenia; Neutrophils; Pediatrics; Phagocytes; Stem Cell Research EN Beijing People's Republic of China Asia Agranulocytosis Autoimmune Diseases and Conditions Autoimmunity Blood Cells Bone Marrow Cells Drugs and Therapies Granulocytes Health and Medicine Hematologic Diseases and Conditions Hematology Hematopoietic Stem Cells Hemic and Immune Systems Hemic and Lymphatic Diseases and Conditions Immune System Diseases and Conditions Immunology Leukocyte Diseases and Conditions Leukocyte Disorders Leukopenia Neutropenia Neutrophils Pediatrics Phagocytes Stem Cell Research 87 87 1 05/08/23 20230512 NES 230512 2023 MAY 13 (NewsRx) -- By a News Reporter-Staff News Editor at Pediatrics Week -- New research on Leukocyte Diseases and Conditions - Neutropenia is the subject of a report. According to the news reporters, the research concluded: "Autoimmune diseases with ELANE mutations associated with neutropenia can be cured through allogeneic hematopoietic stem cell transplantation.". [Extracted from the article]

Keywords: Beijing; People's Republic of China; Asia; Blood Cells; Blood Transfusion; Cardiovascular Diseases and Conditions; Granulocytes; Health and Medicine; Hemic and Immune Systems; Immunology; Ischemia; Ischemia-Reperfusion Injury; Medical Devices; Neutrophils; Phagocytes; Reperfusion; Reperfusion Injury; Transfusion Medicine; Vascular Diseases and Conditions EN Beijing People's Republic of China Asia Blood Cells Blood Transfusion Cardiovascular Diseases and Conditions Granulocytes Health and Medicine Hemic and Immune Systems Immunology Ischemia Ischemia-Reperfusion Injury Medical Devices Neutrophils Phagocytes Reperfusion Reperfusion Injury Transfusion Medicine Vascular Diseases and Conditions 209 209 1 04/03/23 20230403 NES 230403 2023 APR 6 (NewsRx) -- By a News Reporter-Staff News Editor at Cardiovascular Week -- Research findings on Cardiovascular Diseases and Conditions - Reperfusion Injury are discussed in a new report. Beijing, People's Republic of China, Asia, Blood Cells, Blood Transfusion, Cardiovascular Diseases and Conditions, Granulocytes, Health and Medicine, Hemic and Immune Systems, Immunology, Ischemia, Ischemia-Reperfusion Injury, Medical Devices, Neutrophils, Phagocytes, Reperfusion, Reperfusion Injury, Transfusion Medicine, Vascular Diseases and Conditions. [Extracted from the article]

Additionally, low-LMR patients who had undergone incomplete chemotherapy had a shorter median OS compared with those who completed chemotherapy treatment (48.5 vs. 105.9 months, p = 0.026)." Keywords: Blood Cells; Bone Marrow Cells; Cancer; Cell Research; Chemotherapy; Drugs and Therapies; Gynecology; Health and Medicine; Hemic and Immune Systems; Immunology; Lymphocytes; Monocytes; Mononuclear Leukocytes; Mononuclear Phagocyte System; Oncology; Ovarian Cancer; Phagocytes; Surgery; Women's Health EN Blood Cells Bone Marrow Cells Cancer Cell Research Chemotherapy Drugs and Therapies Gynecology Health and Medicine Hemic and Immune Systems Immunology Lymphocytes Monocytes Mononuclear Leukocytes Mononuclear Phagocyte System Oncology Ovarian Cancer Phagocytes Surgery Women's Health 309 309 1 04/03/23 20230404 NES 230404 2023 APR 4 (NewsRx) -- By a News Reporter-Staff News Editor at Women's Health Weekly -- Investigators publish new report on ovarian cancer. [Extracted from the article]