1. Papillary Thyroid Carcinoma-Variants and Associated Disorders.
- Author
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RAVINDRA, SAVITHRI and KAVYASHRI, H. B.
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AUTOIMMUNE thyroiditis , *THYROID cancer , *PAPILLARY carcinoma , *MEDICAL sciences , *THYROID gland - Abstract
Introduction: Papillary Thyroid Carcinoma (PTC) is a malignant epithelial tumour. It is the most common form of thyroid cancer. Several variants have been described like classic, follicular, tall cell, diffuse sclerosing, papillary microcarcinoma and others. Aim: To study the variants of PTC and to evaluate the presence of associated disorders. Materials and Methods: Total of 41 cases of PTC were studied retrospectively from January 2016 to December 2018 in the Department of Pathology, Kempegowda Institute of Medical Sciences, Bengaluru, Karnataka, India. Demographic data and clinical findings were retrieved from case files. The histopathological slides were studied and the results were analysed using Fischer's-exact test using R (Robert Gentleman and Ross Ihaka) statistical Software version 4.0.0. Results: Total data of 41 cases of PTC was collected and analysed. The patient age range between 20 to 70 years with mean age of 47 years. Female preponderance was noted. Among 41 cases, most were classic variant (31, 75.6%) followed by follicular variant (6, 14.6%), papillary microcarcinoma (3, 7.31%) and diffuse sclerosing variant (1, 2.4%). Multinodular goiter was associated with 8 cases of PTC and Hashimoto's thyroiditis was associated with 5 cases of PTC. Among 13 cases of associated disorders, only 6 had preoperative diagnosis of PTC and remaining 7 cases were diagnosed on histopathological examination. Conclusion: Classic variant is the most common type of PTC. All thyroidectomies done for multinodular goiter and Hashimoto's thyroiditis should be screened thoroughly for PTC especially microcarcinoma. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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