1. Comparative chemical study and cytotoxic activity of Uvariodendron angustifolium essential oils from Benin.
- Author
-
Noudogbessi JP, Gary-Bobo M, Adomou A, Adjalian E, Alitonou GA, Avlessi F, Garcia M, Sohounhloue DC, and Menut C
- Subjects
- Benin, Gas Chromatography-Mass Spectrometry, Humans, MCF-7 Cells, Plant Extracts analysis, Annonaceae chemistry, Antineoplastic Agents, Phytogenic pharmacology, Oils, Volatile analysis, Oils, Volatile pharmacology
- Abstract
This study aimed to compare the chemical composition of volatile extracts obtained by hydrodistillation of leaves, stems, bark and roots of Uvariodendron angustifolium (Engl. & Diels) R. E. Fries. The essential oils, obtained with yields between 0.12 and 0.66%, were analyzed by GC/FID and GC/MS. A great variability in the chemical composition was observed depending on the plant part treated. The essential oils obtained from leaves and stems contained mainly neral (29.7-30.5%) and geranial (42.9-47.3%), while methyl eugenol was the major component of the volatile extracts from bark (68.3%) and roots (85.3%). Interesting cytotoxic properties of these essential oils on human breast cancer cells MCF-7 were demonstrated.
- Published
- 2014