1. Relationship between microcephaly and Zika virus during pregnancy: a review.
- Author
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Santos GRBD, Aragão FBA, Lobão WJM, Lima FR, Andrade LMRL, Furtado QR, and Batista JE
- Subjects
- Brazil epidemiology, Disease Outbreaks, Female, Humans, Microcephaly diagnosis, Pregnancy, Pregnancy Complications, Infectious diagnosis, Zika Virus isolation & purification, Zika Virus Infection diagnosis, Microcephaly epidemiology, Microcephaly virology, Pregnancy Complications, Infectious epidemiology, Pregnancy Complications, Infectious virology, Zika Virus Infection complications, Zika Virus Infection epidemiology
- Abstract
Aim: the present study analysed the association between Zika-virus and microcephaly during the gestational period of women in Brazil., Methodology: Systematic reviews of intervention research, current publications of clinical investigations were used systematic search strategies in three electronic databases PubMed, SciELO and Google academic. The following keywords were used: Microcephaly, gestation, Zika-virus to perform the search, and 1020 articles were obtained after exclusion, 45 were left and 35 were eligible. The collection period was from 2004 to 2017., Results: Epidemiological data suggest a temporal association between the quantitative increase and the Zika-virus epidemic, especially in Northeast Brazil. It is not consensual to measure the cephalic perimeter curve to be considered., Conclusion: Given this, the application of techniques to accurately diagnose the relationship between causes and effects in the pathogenesis of Zika virus infection in the central nervous system should be prioritized.
- Published
- 2018
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