1. Characterisation of ocular involvement in an experimental model of neuroschistosomiasis mansoni.
- Author
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Fidelis TAA, Brasileiro-Filho G, Santos HH, Vasconcelos-Santos DV, Parreiras PM, Coelho PMZ, Araujo N, Chaud MV, and Lambertucci JR
- Subjects
- Animals, Brazil, Disease Models, Animal, Eye Infections, Parasitic pathology, Eye Infections, Parasitic physiopathology, Male, Mice, Neuroschistosomiasis pathology, Neuroschistosomiasis physiopathology, Schistosoma mansoni isolation & purification, Schistosomiasis mansoni pathology, Schistosomiasis mansoni physiopathology, Eye Infections, Parasitic parasitology, Neuroschistosomiasis parasitology, Schistosomiasis mansoni parasitology
- Abstract
The Global Burden of Disease Study 2010 listed schistosomiasis among the leading 100 causes of death in Brazil, responsible for 3.6% of the estimated total of deaths globally. Eye and adnexa are very rarely affected by schistosomiasis mansoni, with limited documentation of ocular pathology in this setting. This short communication reports ocular histolopathological findings in a murine model of neuroschistosomiasis mansoni. Lesions were found in the bulbar conjunctiva, lacrimal gland, choroid and corneoscleral limbus.
- Published
- 2019
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