1. UNUSUAL MORPHOLOGIES OF Cryptococcus spp. IN TISSUE SPECIMENS: REPORT OF 10 CASES.
- Author
-
Gazzoni, Alexandra Flávia, Oliveira, Flávio de Mattos, Salles, Emily Ferreira, Mayayo, Emilio, Guarro, Josep, Capilla, Javier, and Severo, Luiz Carlos
- Subjects
CRYPTOCOCCUS ,ANIMAL morphology ,YEAST-like fungi ,SILVER staining (Microscopy) ,MUCOPOLYSACCHARIDES ,BACTERIAL antigens ,EOSIN ,HIV infections - Abstract
Ten cases of cryptococcosis due to unusual microscopic forms of Cryptococcus sp. observed over a twenty-eight year period (1981-2009) are presented. The most important clinicopathological and laboratory data are tabulated. The uncommon forms of cryptococcal cells given are: structures resembling germ tube (one case), chains of budding yeasts (one case), pseudohyphae (two cases) and nonencapsulated yeast-like organisms (eight cases). The diagnosis was based on the histopathological findings. The causative organism was isolated and identified in seven cases; five were due to C. neoformans, and two to C. gattii. In addition, the importance of using staining histochemical techniques - Grocott’s silver stain (GMS), Mayer’s mucicarmine stain (MM) and Fontana-Masson stain (FM) - in the diagnosis of cryptococcosis is argued. [ABSTRACT FROM AUTHOR]
- Published
- 2010
- Full Text
- View/download PDF