1. Clinical and epidemiological characteristics of childhood vitiligo: a study of 701 patients from Brazil.
- Author
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Martins CPDS, Hertz A, Luzio P, Paludo P, and Azulay-Abulafia L
- Subjects
- Adolescent, Age of Onset, Brazil epidemiology, Child, Child, Preschool, Comorbidity, Female, Humans, Infant, Infant, Newborn, Male, Nevus, Halo epidemiology, Retrospective Studies, Vitiligo genetics, Vitiligo pathology, Vitiligo epidemiology, Vitiligo etiology
- Abstract
Background: Vitiligo is an acquired pigmentary disorder that affects approximately 0.5-2% of the world's population, and 25% of cases begin before 10 years of age. Although prevalent, there are few studies on the characterization of childhood vitiligo., Objective: To evaluate the clinical and epidemiological characteristics of childhood vitiligo., Methods: Transverse study conducted by reviewing data records of patients under the age of 18 in which disease onset occurred before 13 years of age., Results: Predominance of females (62%). The most common subtype was generalized vitiligo (53.8%). The average age of disease onset was 5.9 years. The most affected initial site was head/neck (44.22%). The Koebner phenomenon was present in 38.2%, emotional triggering factors in 67.0% of the patients, halo nevus in 17.4%, and associated autoimmune disease in 6.5% of the patients. Family history of vitiligo was observed in 16.9% of the patients, and stability was reported by 20.1% of patients. The presence of positive family history did not significantly influence the age of onset. We found a significant difference between segmental vitiligo (SV) and nonsegmental vitiligo (NSV) regarding the age of onset, Koebner phenomenon, hypothyroidism, anti-TPO antibodies, family history of psoriasis, and halo nevus., Conclusion: Childhood vitiligo has its own characteristics. Vitiligo different subtypes have distinct characteristics. Our study presents a great number of patients, helping to elucidate the peculiarities of childhood vitiligo in the Brazilian population., (© 2019 The International Society of Dermatology.)
- Published
- 2020
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