1. Two new triterpenes from the roots of Pfaffia glomerata.
- Author
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Lian, Lian, Feng, Yuan, Li, Yan-Wu, Bei, Bei, Tang, Ye-Tian, Wang, Hao, Feng, Qing-Mei, and Chen, Gang
- Subjects
ANTI-inflammatory agents ,DIETARY supplements ,EPITHELIAL cells ,MOLECULAR structure ,RESEARCH funding ,PLANT roots ,SPECTROPHOTOMETRY ,TERPENES ,PHYTOCHEMICALS ,PLANT extracts ,PHARMACODYNAMICS - Abstract
Pfaffia paniculata is a commercialized dietary supplement used as the substitute for the Asian ginseng in Brazil. We conducted the systematic isolation of the EtOAc fraction with anti-inflammatory effect and two new triterpenoids, along with 26 known compounds were characterized by means of MS and NMR analysis. Interestingly, the new compound 1 is the first seco-ring triterpenoid reported in the Pfaffia genus. Furthermore, among the known compounds, 14 and 15 exhibited anti-inflammatory activity in Caco-2 cells, but two new compounds showed no anti-inflammatory. [ABSTRACT FROM AUTHOR]
- Published
- 2019
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