1. Hyperpigmented macules on the face of young children: a series of 25 cases.
- Author
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Hernández-Martín A, Gilliam AE, Baselga E, Vicente A, Lam J, González-Enseñat M, Azorín D, and Torrelo A
- Subjects
- Age Factors, Biopsy, Needle, British Columbia, California, Child, Preschool, Cohort Studies, Facial Dermatoses epidemiology, Facial Dermatoses pathology, Female, Follow-Up Studies, Humans, Hyperpigmentation pathology, Immunohistochemistry, Infant, Male, Retrospective Studies, Risk Assessment, Sex Factors, Spain, Time Factors, Facial Dermatoses diagnosis, Hyperpigmentation diagnosis, Hyperpigmentation epidemiology
- Abstract
Background: Acquired hyperpigmented lesions in early childhood can be the presenting sign of serious diseases or benign conditions and often cause significant parental anxiety., Objective: We sought to report a series of 25 young children with hyperpigmented macules on the forehead and temples without preceding erythema, edema, or desquamation., Methods: We conducted a retrospective review of 25 children with similar clinical findings, seen from 2009 to 2013, from 5 medical centers in 3 countries., Results: There were 13 boys and 12 girls of many races. Their ages ranged from 2 to 24 months (mean 12.2 months, median 6 months). The hyperpigmentation presented abruptly in the summer (12 cases), spring (5 cases), winter (5), and fall (2), and was not clearly specified in 1 case. Histopathologic analysis in 3 cases was consistent with postinflammatory hyperpigmentation. After a follow-up period ranging from 3 months to 4.5 years, the lesions persist to a variable degree in 19 cases in which follow-up was possible., Limitations: The age of our patients precluded patch testing and/or invasive diagnostic methods., Conclusions: The clinical features and prolonged clinical course over years do not correspond with any known or previously described cause of acquired facial hyperpigmented macules in young children., (Copyright © 2013 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved.)
- Published
- 2014
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