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This study identifies a theoretical mechanism that could potentially affect public university admissions standards in a context of demographic change. I explore how demographic changes at a prestigious public university in the United States affect individuals' evaluations of college applications. Responding to a line graph that randomly displays a freshmen enrollment trend toward a white plurality or an Asian American plurality, white student evaluators lower their minimum class rank standard for admitting white applicants when exposed to an Asian American plurality trend. They also raise the minimum test percentile standard for admitting Asian American applicants. Notably, plurality trend does not affect Asian American student evaluators' minimum standards for recommending admission. Applications differed only by applicant race.

Historically, wildfire and tribal burning practices played important roles in shaping ecosystems throughout the Klamath Siskiyou Bioregion of northern California and southern Oregon. Over the past several decades, there has been increased interest in the application of fire for forest management through the implementation of prescribed fires within habitats that are used by a diversity of migrant and resident land birds. While many bird species may benefit from habitat enhancements associated with wildfires, cultural burning, and prescribed fire, individuals may face direct or indirect harm. In this study, we analyzed the timing of breeding and molting in 11 species of culturally significant land birds across five ecologically distinct regions of northern California and southern Oregon to explore the potential timeframes that these bird species may be vulnerable to wildland fires (wildfire, prescribed fire, or cultural burning). We estimated that these selected species adhered to a breeding season from April 21 to August 23 and a molting season from June 30 to October 7 based on bird capture data collected between 1992 and 2014. Within these date ranges, we found that breeding and molting seasons of resident and migratory bird species varied temporally and spatially throughout our study region. Given this variability, spring fires that occur prior to April 21 and fall fires that occur after October 7 may reduce the potential for direct and indirect negative impacts on these culturally significant birds across the region. This timing corresponds with some Indigenous ecocultural burning practices that are aligned with traditionally observed environmental cues relating to patterns of biological phenology, weather, and astronomy. We detail the timing of breeding and molting seasons more specific to regions and species, and estimate 75%, 50%, and 25% quartiles for each season to allow for greater flexibility in planning the timing of prescribed fires and cultural burning, or regarding the potential implications of wildfires. The results of our study may serve as an additional resource for tribal members and cultural practitioners (when examined within the context of Indigenous Traditional Ecological Knowledge) and forest and wildland fire managers to promote stable populations of culturally significant bird species within fire‐dependent forest systems. [ABSTRACT FROM AUTHOR]

As a substance is heated at constant pressure from near 0 K to 298 K, each incremental enthalpy increase, dH, alters entropy by dH/T, bringing it from approximately zero to its standard molar entropy S degrees. Using heat capacity data for 32 solids and CODATA results for another 45, we found a roughly linear relationship between S degrees and deltaH degrees. The plot showing the relationship S degrees is approximately equal to (constant) deltaH degrees, with constant = 0.0066 K[superscript -1], for 77 solids can serve as an enlightening visualization of this relationship for students in general chemistry. The near-linearity can be understood qualitatively in terms of lattice vibrations and internal vibrations within polyatomic units, which are reflected by molar heat capacities and Debye temperatures. This study supports the thesis that thermodynamic entropy and stored internal energy in a solid are intimately related and that entropy can be usefully interpreted as a spreading function, as described in the text. (Contains 4 figures, 1 table, and 11 notes.)

We examine the cyclic amplitude variation of seismic noise recorded by continuous three-component broad-band seismic data with durations spanning 91–713 d (2008–2011) from three different networks: Anza seismic network, IDA network and the transportable seismic array. These stations surround the San Jacinto Fault Zone (SJFZ) in southern California. We find the seismic noise amplitudes exhibit a cyclical variation between 0.3 and 7.2 Hz. The high-frequency (≥0.9 Hz) noise variations can be linked to human activity and are not a concern. Our primary interest is signals in the low frequencies (0.3–0.9 Hz), where the seismic noise is modulated by semi-diurnal tidal mode M 2. These long-period (low-frequency) variations of seismic noise can be attributed to a temporal change of the ocean waves breaking at the shoreline, driven by ocean tidal loading. We focus on the M 2 variation of seismic noise at f  = 0.6 Hz, travelling distances of ∼92 km through the crust from offshore California to the inland Anza, California, region. Relative to the shoreline station, data from the inland stations show a phase lag of ∼ –12°, which we attribute to the cyclic change in M 2 that can alter crustal seismic attenuation. We also find that for mode M 2 at 0.6 Hz, the amplitude variations of the seismic quality factor (Q) depend on azimuth and varies from 0.22 per cent (southeast to northwest) to 1.28 per cent (northeast to southwest) with Q  = 25 for Rayleigh waves. We propose the direction dependence of the Q variation at 0.6 Hz reflects the preferred orientation of subfaults parallel to the main faulting defined by the primarily N45°W strike of the SJFZ. [ABSTRACT FROM AUTHOR]

We image the internal structure of the San Jacinto fault zone (SJFZ) near Anza, California, with seismic data recorded by two dense arrays (RA and RR) from ∼42 000 local and ∼180 teleseismic events occurring between 2012 and 2017. The RA linear array has short aperture (∼470 m long with 12 strong motion sensors) and recorded for the entire analysed time window, whereas the RR is a large three-component nodal array (97 geophones across a ∼2.4 km × 1.4 km area) that operated for about a month in September–October 2016. The SJFZ at the site contains three near-parallel surface traces F1, F2 and F3 from SW to NE that have accommodated several M w > 6 earthquakes in the past 15 000 yr. Waveform changes in the fault normal direction indicate structural discontinuities that are consistent with the three fault surface traces. Relative slowness from local events and delay time analysis of teleseismic arrivals in the fault normal direction suggest a slower SW side than the NE with a core damage zone between F1 and F2. This core damage zone causes ∼0.05 s delay at stations RR26–31 in the teleseismic P arrivals compared with the SW-most station, and generates both P - and S -type fault zone trapped waves. Inversion of S trapped waves indicates the core damaged structure is ∼100 m wide, ∼4 km deep with a Q value of ∼20 and 40 per cent S -wave velocity reduction compared with bounding rocks. Fault zone head waves observed at stations SW of F3 indicate a local bimaterial interface that separates the locally faster NE block from the broad damage zone in the SW at shallow depth and merges with a deep interface that separates the regionally faster NE block from rocks to the SW with slower velocities at greater depth. The multiscale structural components observed at the site are related to the geological and earthquake rupture history at the site, and provide important information on the preferred NW propagation of earthquake ruptures on the San Jacinto fault. [ABSTRACT FROM AUTHOR]

We present results from complementary geological, topographic, seismic and electrical resistivity surveys at the Sagebrush Flat (SGB) site along the Clark fault (CF) strand of the San Jacinto fault zone trifurcation area southeast of Anza, California. Joint interpretation of these data sets, each with unique spatiotemporal sensitivities, allow us to better characterize the shallow (<100 m) fault zone at this structurally complex site. Geological mapping at the surface shows the CF has three main subparallel strands within a <100 m zone with varying degrees of rock damage. These strands intersect units of banded gneiss and tonalite, and various sedimentary units. Near the surface, the weathered but more intact tonalite and gneiss to the southwest have relatively high VP. The low-lying flat sedimentary basins around the two southwestern-most CF strands and elevated damaged gneiss to the northeast have lowest VP <500 m s–1. The high relief of the northeast gneiss unit may in part be explained by its extensive damage and inferred increased relative rock uplift. Resistivity imaging shows the unconsolidated dry basin sediments (maximum >1300 Ohm.m) contrasted against the compacted fine-grained (potentially wet) materials within the CF core and the Bautista Formation (minimum <40 Ohm.m), which is slightly elevated above the flat basins. The inverse relationship between VP (increases) and resistivity (decreases) in the uppermost ∼15 m can be characterized as log–log linear with slopes of –2.6 to –4. At depths >30 m, the velocity heterogeneity near the surface merges into larger-scale structures that are generally slower on the northeast side of the CF core compared to the southwest side (as much as ∼40 per cent reduction in average VP). A previous study revealed a 20–37 per cent variability in peak ground velocities across the SGB site from local earthquakes. The upper end of that range is associated with the near-surface unconsolidated sedimentary basins and northeast damaged gneiss unit. Preliminary analysis of time-dependent topography mostly shows effects of changing vegetation and anthropogenic activity. [ABSTRACT FROM AUTHOR]

We develop an automated processing procedure to derive a new catalog of earthquake locations, magnitudes, and potencies and analyze 9 years of data between 2008 and 2016 in the San Jacinto fault‐zone region. Our procedure accounts for detailed 3‐D velocity structure using a probabilistic global‐search location inversion and obtains high‐precision relative event locations using differential travel times measured by cross‐correlating waveforms. The obtained catalog illuminates spatiotemporal seismicity patterns in the fault zone with observations for 108,800 earthquakes in the magnitude range −1.8 to 5.4. Inside a focus region consisting of an 80‐km by 50‐km rectangle oriented parallel to the main fault trace, we estimate a 99% detection rate of earthquakes with magnitude 0.6 and greater and detect and locate about 60% more events than those present in the Southern California Seismic Network catalog. The results provide the most complete catalog available for the focused study region during the analyzed period and include both deeper events and very shallow patches of seismicity not present in the regional catalog. The seismicity exhibits a variety of complex patterns that contain important information on deformation processes in the region. The fraction of event pairs with waveforms having cross‐correlation coefficients ≥0.95 is only about 3%, indicating diverse processes operating in the fault zone. Key Points: We develop an automated procedure to derive a catalog of earthquake locations and sizes from raw waveform dataWe derive a new catalog for the San Jacinto fault zone region with 108,800 events between 2008 and 2016We interpret variable mechanical properties of fault‐zone regions from seismicity patterns [ABSTRACT FROM AUTHOR]

Local and teleseismic earthquake waveforms recorded by a 180-m-long linear array (BB) with seven seismometers crossing the Clark fault of the San Jacinto fault zone northwest of Anza are used to image a deep bimaterial interface and core damage structure of the fault. Delay times of P waves across the array indicate an increase in slowness from the southwest most (BB01) to the northeast most (BB07) station. Automatic algorithms combined with visual inspection and additional analyses are used to identify local events generating fault zone head and trapped waves. The observed fault zone head waves imply that the Clark fault in the area is a sharp bimaterial interface, with lower seismic velocity on the southwest side. The moveout between the head and direct P arrivals for events within ~40 km epicentral distance indicates an average velocity contrast across the fault over that section and the top 20 km of 3.2 per cent. A constant moveout for events beyond ~40 km to the southeast is due to off-fault locations of these events or because the imaged deep bimaterial interface is discontinuous or ends at that distance. The lack of head waves from events beyond ~20 km to the northwest is associated with structural complexity near the Hemet stepover. Events located in a broad region generate fault zone trapped waves at stations BB04-BB07. Waveform inversions indicate that the most likely parameters of the trapping structure are width of ~200 m, S velocity reduction of 30-40 per cent with respect to the bounding blocks, Q value of 10-20 and depth of ~3.5 km. The trapping structure and zone with largest slowness are on the northeast side of the fault. The observed sense of velocity contrast and asymmetric damage across the fault suggest preferred rupture direction of earthquakes to the northwest. This inference is consistent with results of other geological and seismological studies. [ABSTRACT FROM AUTHOR]

Kappa is a one-parameter estimator of the spectral amplitude decay with frequency of a seismogram. Low values (~5 ms) indicate limited attenuation of highfrequency energy whereas higher values (~40 ms) indicate high-frequency energy has been removed. Kappa is often assumed to be a site term and used in seismic designs. We address two key questions about kappa: (1) how to identify source, path, and site contributions to kappa; and (2) can kappa estimates from smaller earthquakes, and more readily accessible weak-motion recordings, be reasonably extrapolated to estimate kappa of larger earthquakes? The use of small earthquakes (ML < 1) presents many challenges and requires new approaches. We develop estimates of kappa for seismograms from 1137 small earthquakes recorded by the ANZA seismic network in southern California, and compare these to results from the stronger recorded shaking generated by 43 ML > 3.5 earthquakes inside the network. We find kappa from small earthquakes predicts the relative values of kappa for larger earthquakes (e.g., measurements at stations PFO and KNW are small compared with those at stations TRO and SND). For the SND and TRO data, however, kappa values from small earthquakes overpredict those from moderate and large earthquakes. Site effects are the most important contributor to kappa estimates, but the scatter within kappa measurements at a given station is likely caused by a significant contribution from near the source, perhaps related to near-source scattering. Because of this source-side variability, care is recommended in using individual small events as Green's functions to study source-time effects of moderate and large events. [ABSTRACT FROM AUTHOR]

We examine aftershock detectability thresholds for events in the initial part of the 31 October 2001, ML 5.1 sequence in southern California. This sequence occurred directly below the broadband ANZA seismic network, which recorded continuous waveform data at 13 azimuthally well-distributed stations within the study region (seven had epicentral distances < 20 km). Of the 608 aftershocks (0 < ML < ∼2.8) in the initial 2 hr of this sequence, the first five aftershocks recorded were only identifiable at stations within 30 km after applying a high-pass filter. Using a cluster (radius ≤ 1.1 km) of 200 representative aftershocks, we track the maximum seismogram amplitude versus earthquake magnitude. This relationship helps us quantify the visibility of aftershocks within the mainshock coda and assess our detection capabilities. We estimate that detectable aftershocks within the mainshock coda include (1) those over magnitude ∼3 that are within 15 km of the network centroid that occur 12 sec or more into the sequence, and (2) those over magnitude ∼2 that are within 30 km of the centroid of the network that occur 60 sec or more into the sequence. We find a lack of large aftershocks in this sequence. The largest aftershock (ML ∼2.8) is substantially smaller than the mainshock (ML 5.1). We suggest this relatively large-magnitude differential is dictated by a combination of factors that includes complexity of the San Jacinto fault system and the lack of large earthquakes in the region in the past ∼20 years. [ABSTRACT FROM AUTHOR]

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Provides information on the 12th annual meeting of the PanAmerican Society for Pigment Cell Research to be held at the Sutton Place Hotel in Newport Beach, California on June 24 to 27, 2004. Theme of the meeting; Overall objectives of the event; Invited speakers.

Objective: Identify non-distance factors related to children's active transport (AT) to school, including parental, home, and environment characteristics. Understanding the factors related to children's AT to school, beyond distance to school, could inform interventions to increase AT and children's overall physical activity. Study design: Participants were in the Neighborhood Impact on Kids Study, a longitudinal, observational cohort study of children aged 6-11 and their parents in King County, WA and San Diego County, CA between 2007 and 2009. Parents reported frequency and mode of child transport to school, perceived neighbourhood, home and family environments, parental travel behaviours, and sociodemographics. Methods: Children living less than a 20 minute walk to school were in this analysis. Children classified as active transporters (walked/bicycled to or from school at least once per week) were compared with those not using AT as often. Results: Children using AT were older and had parents who reported themselves using active transport. Having a family rule that restricts the child to stay within sight of the parent or home and more parent working hours were related to lower odds of a child using AT. Conclusions: Children's AT to school is associated with parental AT to work and other locations. Interventions should be considered that enable whole family AT, ameliorate safety concerns and decrease the need for parental supervision, such as walking school buses. [ABSTRACT FROM AUTHOR]

Background Due in part to the heterogeneity of the pulmonary circulation in patients with tetralogy of Fallot and major aortopulmonary collateral arteries (MAPCAs), research on this condition has focused on relatively basic anatomic characteristics. We aimed to detail pulmonary artery (PA) and MAPCA anatomy in a large group of infants, assess relationships between anatomy and early surgical outcomes, and consider systems for classifying MAPCAs. Methods and Results All infants ( <1 year of age) undergoing first cardiac surgery for tetralogy of Fallot/MAPCAs from 2001 to 2019 at Stanford University were identified. Preoperative angiograms delineating supply to all 18 pulmonary segments were reviewed for details of each MAPCA and the arborization and size of central PAs. We studied 276 patients with 1068 MAPCAs and the following PA patterns: 152 (55%) incompletely arborizing PAs, 48 (17%) normally arborizing PAs, 45 (16%) absent PAs, and 31 (11%) unilateral MAPCAs. There was extensive anatomic variability, but no difference in early outcomes according to PA arborization or the predominance of PAs or MAPCAs. Patients with low total MAPCA and/or PA cross-sectional area were less likely to undergo complete repair. Conclusions MAPCA anatomy is highly variable and essentially unique for each patient. Though each pulmonary segment can be supplied by a MAPCA, central PA, or both, all anatomic combinations are similarly conducive to a good repair. Total cross-sectional area of central PA and MAPCA material is an important driver of outcome. We elucidate a number of novel associations between anatomic features, but the extreme variability of the pulmonary circulation makes a granular tetralogy of Fallot/MAPCA classification system unrealistic.

Background: Children with tetralogy of Fallot, pulmonary atresia, and major aortopulmonary collaterals (TOF/MAPCAs) are at risk for post-operative respiratory complications after undergoing unifocalisation surgery. Thus, we assessed and further defined the incidence of airway abnormalities in our series of over 500 children with TOF/MAPCAs as determined by direct laryngoscopy, chest computed tomography (CT), and/or bronchoscopy., Methods: The medical records of all patients with TOF/MAPCAs who underwent unifocalisation or pulmonary artery reconstruction surgery from March, 2002 to June, 2018 were reviewed. Anaesthesia records, peri-operative bronchoscopy, and/or chest CT reports were reviewed to assess for diagnoses of abnormal or difficult airway. Associations between chromosomal anomalies and airway abnormalities - difficult anaesthetic airway, bronchoscopy, and/or CT findings - were defined., Results: Of the 564 patients with TOF/MAPCAs who underwent unifocalisation or pulmonary artery reconstruction surgery at our institution, 211 (37%) had a documented chromosome 22q11 microdeletion and 28 (5%) had a difficult airway/intubation reported at the time of surgery. Chest CT and/or peri-operative bronchoscopy were performed in 234 (41%) of these patients. Abnormalities related to malacia or compression were common. In total 35 patients had both CT and bronchoscopy within 3 months of each other, with concordant findings in 32 (91%) and partially concordant findings in the other 3., Conclusion: This is the largest series of detailed airway findings (direct laryngoscopy, CT, and bronchoscopy) in TOF/MAPCAS patients. Although these findings are specific to an at-risk population for airway abnormalities, they support the utility of CT and /or bronchoscopy in detecting airway abnormalities in patients with TOF/MAPCAs.

Background: A 22q11 chromosome deletion is common in patients with tetralogy of Fallot, pulmonary atresia, and major aortopulmonary collaterals. We sought to determine whether 22q11 chromosome deletion is associated with increased postoperative morbidity after unifocalisation surgery., Methods: We included all patients with this diagnosis undergoing primary or revision unifocalisation ± ventricular septal defect closure at our institution from 2008 to 2016, and we excluded patients with unknown 22q11 status. Demographic and surgical data were collected. We compared outcomes between those with 22q11 chromosome deletion and those without using non-parametric analysis., Results: We included 180 patients, 41% of whom were documented to have a chromosome 22q11 deletion. Complete unifocalisation was performed in all patients, and intracardiac repair was performed with similar frequency regardless of 22q11 chromosome status. Duration of mechanical ventilation was longer in 22q11 deletion patients. This difference remained significant after adjustment for delayed sternal closure and/or intracardiac repair. Duration of ICU stay was longer in patients with 22q11 deletion, although no longer significant when adjusted for delayed sternal closure and intracardiac repair. Finally, length of hospital stay was longer in 22q11-deleted patients, but this difference was not significant on unadjusted or adjusted analysis., Conclusion: Children with tetralogy of Fallot, pulmonary atresia, and major aortopulmonary collaterals and 22q11 deletion are at risk for greater prolonged mechanical ventilation after unifocalisation surgery. Careful attention should be given to the co-morbidities of this population in the perioperative period to mitigate risks that may complicate the postoperative course.

Background: There are conflicting reports regarding the importance of mitral stenosis and aortic atresia as a risk factor for Norwood mortality. This study reviews outcomes of this anatomic subgroup at our institution and examines the utility of preoperative cardiac catheterization and its correlation with clinical outcomes and pathology findings., Methods: This is a single-center, retrospective review of hypoplastic left heart syndrome patients who underwent modified Norwood operation between October 2005 and May 2013., Results: Fourteen of 74 hypoplastic left heart syndrome patients (19%) had mitral stenosis and aortic atresia. Operative mortality for MS/AA was 29% versus 7% for all other hypoplastic left heart syndrome anatomic subgroups (p = 0.04). Although only 19% of the entire cohort, the mitral stenosis and aortic atresia subgroup constituted 50% of the total operative mortality and the only interstage deaths. Autopsies support myocardial ischemia as the mechanism of death. Although preoperative angiography defined the presence of ventriculo-coronary connections, it did not clearly risk stratify patients in regard to operative mortality., Conclusions: Mitral stenosis and aortic atresia is a risk factor for perioperative myocardial ischemia and mortality. Further exploration of myocardial reserve is warranted., (Copyright © 2016 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.)

Background: Complete atrioventricular block (AVB) is a recognized complication of ventricular septal defect (VSD) repair. The objective of this study was to examine incidence and risk factors., Methods: This is a single-center, retrospective study. All pediatric patients (age <18 years) who underwent VSD repair between November 2001 and August 2009 with concordant atrioventricular and ventriculoarterial connections were included. Patients were classified as having no AVB or transient AVB, and outcomes of early pacemaker placement (before hospital discharge) or late pacemaker placement (after hospital discharge) were recorded., Results: Eight hundred twenty-eight patients (48.6% female) underwent VSD repair during the study period. Mean age at repair was 14 ± 29.4 months. A total of 64 patients (7.7%) developed surgical AVB. Among those patients who developed AVB, 48 (75%) had transient AVB. Sixteen patients (1.9%) required a pacemaker, 14 early (88%) and 2 late (12%). Patients <4 kg (4.2% vs. 1%, P ≤ .01) and those with inlet VSDs (11.6% vs. 1.4%, P ≤ .01) were more likely to develop surgical AVB. Surgical AVB was not influenced by the presence of chromosomal abnormalities or other congenital heart disease., Conclusion: The overall incidence of surgical AVB is consistent with previous reports. Weight <4 kg and presence of an inlet VSD were significant risk factors., (© 2013 Wiley Periodicals, Inc.)

Objective: The objectives of this study were (1) to determine the use of temporary epicardial pacing wires to diagnose and treat early postoperative arrhythmias in pediatric cardiac surgical patients and (2) to determine the predictive factors for the need of pacing wires for diagnostic or therapeutic purposes., Methods: We collected preoperative, intraoperative, and postoperative data in a prospective, observational format from patients undergoing pediatric cardiac surgery between August 2010 and January 2011 at a single academic children's hospital., Results: A total of 157 patients met the inclusion criteria during the study period. Of these 157 patients, pacing wires were placed in 127 (81%). Pacing wires were used in 25 patients (19.6%) for diagnostic purposes, 26 patients (20.4%) for therapeutic purposes, 15 patients (11.8%) for both diagnostic and therapeutic purposes, and 36 patients (28.3%) for diagnostic or therapeutic purposes. Need for cardioversion in the operating room, presence of 2 or more intracardiac catheters, severely reduced ventricular ejection fraction, and elevated serum lactate level at the time of operating room discharge were found to be independent predictors for the use of pacing wires. The only complication noted in the cohort was a skin infection at a pacing wire insertion site in 1 patient. A permanent pacemaker was required in 8 (6.2%) of all patients with temporary pacing wires., Conclusions: Our data support the use of temporary epicardial pacing wires in approximately 30% of children after congenital heart surgery. We found the need for cardioversion in the operating room, presence of 2 or more intracardiac catheters, severely reduced ventricular ejection fraction, and high serum lactate level at the time of discharge from the operating room to be independent predictors of the use of pacing wires in the early postoperative period., (Copyright © 2012 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.)

This study builds upon the current literature investigating the relationship between individuals' physical activity and the built environment. This prospective study of two lifestyle interventions in adults explores the moderating effect of the built environment measured both objectively and by self-report. Results show that overweight men in an intervention group increased their walking significantly more if they lived in less walkable neighborhoods. Overweight women were more likely to increase their physical activity over time if they perceived better safety from traffic. This study suggests that psychosocial interventions can help men overcome environmental barriers to walking., (Copyright 2010 Elsevier Ltd. All rights reserved.)

Purpose: Although uncommon, melanoma is associated with poor survival characteristics among African Americans and Hispanics compared with non-Hispanic whites (NHWs). Low socioeconomic status (SES) is also associated with poor survival among patients with melanoma, but it is not known whether this is because of SES itself or because of treatment disparities. We set out to determine this by using the large, population-based California Cancer Registry (CCR) database as a model., Patients and Methods: We conducted a case-only analysis of CCR data (1993 to 2003), including a descriptive analysis of relevant clinical variables and SES. The SES variable used has been derived from principle component analysis of census block-level CCR data that was linked to census data to address seven indicators of SES. Univariate analyses of overall survival (OS) were conducted using the Kaplan-Meier method. Multivariate survival analyses were performed using Cox proportional hazard ratios (HRs)., Results: A total of 39,049 incident patient cases of cutaneous melanoma, including 36,694 in NHWs; 127 in African Americans; 1,996 in Hispanics; and 262 in Asian-Americans, were analyzed. Higher SES was associated with an early stage at presentation (P < .0001), with treatment with surgery (P = .0005), and with prolonged survival (P < .0001). After adjustments for age, sex, histology, American Joint Committee on Cancer stage, anatomic site, treatment, and SES, a statistically significant increased risk of death was observed for African Americans compared with NHWs (HR, 1.60; 95% CI, 1.17 to 2.18); no survival differences were noted for Asians or Hispanics compared with NHWs in the adjusted analysis., Conclusion: Low SES independently predicts poor outcome among patients with cutaneous melanoma. However, the poor OS observed for African American patients with melanoma is not explained by differences in treatment or SES.

Study Design: Retrospective review of the medical, radiographic, surgical, and postoperative records of patients who underwent resection of multilevel intradural extramedullary spinal cord tumors of the ventral cervical and cervicothoracic spine via a modified paramedian transpedicular approach at the University of California, San Francisco, between 2003 and 2005., Objective: To assess the surgical, clinical, and radiographic outcomes of using the modified paramedian transpedicular approach to resect ventral intradural extramedullary spinal cord tumors of the ventral cervical and cervicothoracic spine., Summary of Background Data: A common theme of skull-base surgery for many years has been to remove the bone rather than retract neural elements. In this report, we demonstrate some possible advantages of taking a "spine-base" approach for resecting intradural extramedullary spinal cord tumors of the ventral cervical and cervicothoracic spinal canal, and present our clinical experience., Methods: All medical, surgical, and radiologic records were retrospectively reviewed. Clinical outcome was assessed for disability via the Neck Disability Index and for pain via the visual analog scale., Results: Fourteen patients (4 males and 10 females, average age 39.6 years, range 20-62) with intradural extramedullary spinal cord tumors involving multiple levels of the anterior cervical and cervicothoracic spine were identified. All patients presented with pain and/or radiculomyelopathy attributed to a ventral intradural extramedullary spinal cord tumor of the cervical or cervicothoracic spine that was resected via the modified paramedian transpedicular approach with partial dorsal corpectomy and posterior spinal reconstruction. The average follow-up period was 14.6 months (range 5-30). Gross total resection was achieved in all cases, and no patient required additional surgery via an anterior approach for residual tumor., Conclusions: The modified paramedian transpedicular approach with partial dorsal corpectomy we describe here is a variation of traditional thoracic posterolateral transpedicular extracavitary approaches and offers direct access to lesions of the ventral cervicothoracic spinal canal. This approach avoids the morbidity of anterior transcervical, transoral, or transthoracic procedures, while providing a view of the entire ventral cervicothoracic canal, and can be performed safely and effectively in select patients.