1. Multiple introductions of HIV-1 subtype E into the western hemisphere.
- Author
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Artenstein AW, Coppola J, Brown AE, Carr JK, Sanders-Buell E, Galbarini E, Mascola JR, VanCott TC, Schonbrood P, and McCutchan FE
- Subjects
- Acquired Immunodeficiency Syndrome transmission, Acquired Immunodeficiency Syndrome virology, Adult, Cambodia, Disease Outbreaks, HIV-1 genetics, Humans, Male, Prevalence, Sexual Behavior, Travel, Uruguay epidemiology, Acquired Immunodeficiency Syndrome epidemiology, HIV-1 classification, Military Personnel
- Abstract
There are nine recognised genetic subtypes of HIV-1, and the epidemic in Southeast Asia is largely due to subtype E. We have investigated HIV-1 viral subtypes in 11 Uruguayan military personnel, six with infection acquired during a United Nations deployment to Cambodia and five with infection acquired in South America. We found subtype E in five of the six infections acquired in Southeast Asia, and subtype B in all five of the domestically acquired cases. These findings document multiple introductions of HIV-1 subtype E into the western hemisphere and mean that the genetic diversity of the global HIV-1 pandemic must be considered in strategies for epidemic control.
- Published
- 1995
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