1. Parental report of vaccine receipt in children with autism spectrum disorder: Do rates differ by pattern of ASD onset?
- Author
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Goin-Kochel RP, Mire SS, Dempsey AG, Fein RH, Guffey D, Minard CG, Cunningham RM, Sahni LC, and Boom JA
- Subjects
- Adolescent, Canada, Chickenpox Vaccine administration & dosage, Child, Child, Preschool, Diphtheria-Tetanus-acellular Pertussis Vaccines administration & dosage, Female, Haemophilus Vaccines administration & dosage, Hepatitis B Vaccines administration & dosage, Humans, Male, Measles-Mumps-Rubella Vaccine administration & dosage, Parents, Poliovirus Vaccines administration & dosage, United States, Autism Spectrum Disorder classification, Vaccination statistics & numerical data
- Abstract
A contentious theory espoused by some parents is that regressive-onset of autism spectrum disorder (ASD) is triggered by vaccines. If this were true, then vaccine receipt should be higher in children with regressive-onset ASD compared with other patterns of onset. Parental report of rate of receipt for six vaccines (DPT/DTaP, HepB, Hib, polio, MMR, varicella) was examined in children with ASD (N=2755) who were categorized by pattern of ASD onset (early onset, plateau, delay-plus-regression, regression). All pairwise comparisons were significantly equivalent within a 10% margin for all vaccines except varicella, for which the delay-plus-regression group had lower rates of receipt (81%) than the early-onset (87%) and regression (87%) groups. Findings do not support a connection between regressive-onset ASD and vaccines in this cohort., (Copyright © 2016 Elsevier Ltd. All rights reserved.)
- Published
- 2016
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