1. The Impact of Quadriceps Muscle Layer Thickness on Length of Stay of Patients Listed for Renal Transplant.
- Author
-
Levine, Max, Luke, Patrick, Sener, Alp, Resvick, Heather, Braga, Stephanie, St. Kitts, Taralynn, De Marinis, Sarah, and Madill, Janet
- Subjects
LENGTH of stay in hospitals ,PREOPERATIVE care ,BODY composition ,FRAIL elderly ,SCIENTIFIC observation ,MULTIPLE regression analysis ,KIDNEY transplantation ,SARCOPENIA ,SURGICAL complications ,MANN Whitney U Test ,FISHER exact test ,T-test (Statistics) ,QUADRICEPS muscle ,CHI-squared test ,DESCRIPTIVE statistics ,RESEARCH funding ,DATA analysis software ,LONGITUDINAL method - Abstract
Background: Quadriceps muscle layer thickness (QMLT), which is measured using ultrasound, is an emerging strategy to identify sarcopenia. Purpose: The purpose of the study was to assess whether pre-operative QMLT values are associated with a prolonged length of stay (LOS; defined as >14 days) following a renal transplant. Methods: Between March 2019 and January 2020, we performed a prospective study among patients undergoing renal transplantation. Physical Frailty scores and QMLT measurements were performed pre-operatively. The primary outcome was a greater LOS following transplant. Secondary outcomes included complications and renal function. Statistical analysis: Percentiles divided patients into two categories of QMLT (low and high). Continuous outcomes were compared using a two-sided t-test or Mann–Whitney U test, and Chi-square analysis and Fisher exact testing were used for nominal variables. Results: Of 79 patients, the frailty prevalence was 16%. Among patients with low and higher QMLTs, LOS of >14 days were 21% vs. 3% [p = 0.04], respectively. Demographically, there was a higher percentage of patients with living donors in the high- vs. low-QMLT groups (40 vs. 7%). However, in a subgroup analysis excluding living-donor recipients, the difference between groups was preserved (23% vs. 0%, p = 0.01). No differences in secondary outcomes were seen between groups. Conclusions: Low quadriceps muscle layer thickness may be associated with a prolonged length of stay for renal recipients. Further research is needed to confirm our findings. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF