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A report from the University of Guadalajara discusses the impact of chronic fluoride exposure on dental health and growth in male Wistar rats at different developmental stages. The study found that prolonged exposure to fluoride can have adverse effects on different tissues, and it can cross the placental barrier and be present in breast milk, leading to prenatal exposure. The research showed that high concentrations of fluoride had negative effects on adult individuals, including reproductive and developmental effects. The study also highlighted that the effects of chronic fluoride exposure vary depending on the developmental stage of the individual at the time of exposure. [Extracted from the article]

A recent study conducted by researchers from the University of Guadalajara in Mexico explored the electroencephalographic (EEG) activity in the brains of primiparous breastfeeding mothers during direct breastfeeding and breast milk expression. The study found that mothers reported higher valence and arousal, as well as a pleasant state, during direct breastfeeding compared to breast milk expression. EEG activity in the prefrontal and parietal cortices was also found to be different between the two conditions, suggesting that direct breastfeeding may involve a state of focused attention and integration of emotional and cognitive processes. This research provides valuable insights into the mother-baby interaction during breastfeeding. [Extracted from the article]

A recent study conducted by researchers from the University of Guadalajara in Mexico has found that certain strains of Lactobacillus bacteria and their extracts have the potential to counteract the genotoxicity and oxidative stress caused by acrylamide, a compound found in many thermally processed food products. The researchers used Lactobacillus caseiShirota and Lactobacillus reuteriNRRL B-14171 strains, which were cultured and subjected to mechanical and enzymatic treatments to obtain intra and extracellular extracts. The study found that both strains and their extracts demonstrated the ability to reduce lipid peroxidation and genotoxicity caused by acrylamide. These findings suggest that the use of Lactobacillus extracts could be a viable alternative for reducing the harmful effects of acrylamide without the need for live bacteria. [Extracted from the article]

Researchers at the University of Guadalajara in Mexico have conducted a study on the phytoestrogenic effects of hibiscus sabdariffa, a plant known for its high anthocyanin content. The study focused on the impact of hibiscus sabdariffa on estrogen receptors in ovariectomized Wistar rats, which experience a rapid decline in ovarian hormone production. The researchers found that hibiscus sabdariffa extract and estradiol affected the expression of estrogen receptors differently, suggesting that hibiscus sabdariffa could be a potential alternative to hormone replacement therapy. Further research is needed to explore the use of hibiscus sabdariffa as a nutrition-based alternative to hormone replacement therapy. [Extracted from the article]

A study conducted by the Mexican Social Security Institute in Jalisco, Mexico, has found that beta-caryophyllene (BCP) has neuroprotective effects on dopaminergic neurons in a model of hemiparkinsonism. BCP, which activates the type 2 cannabinoid receptor, demonstrated antioxidant and anti-inflammatory properties, leading to improvements in motor dysfunction and inhibition of the NLRP3 inflammasome. The study suggests that BCP has the potential to mitigate motor deficits and reduce neuroinflammation in Parkinson's disease. The research was supported by the Consejo Nacional de Humanidades, Ciencias y Tecnologias (CONAHCYT) and has been peer-reviewed. [Extracted from the article]

New research from Jalisco, Mexico explores the proteome and immunogenicity differences between the BCG Pasteur ATCC 35734 strain and its derivative, the vaccine candidate BCGDBCG1419c, during planktonic growth in different media. The study found that both the presence or absence of the BCG1419c gene and the culture medium affected the proteome produced in vitro, potentially leading to changes in the capacity to induce immune responses. The research suggests that modifications in the antigenic repertoire of the BCG vaccine may arise from in vitro growth conditions, which could contribute to the variable efficacy of the vaccine in preventing tuberculosis. [Extracted from the article]

Jalisco, Mexico, North and Central America, Enterobacteriaceae, Foodborne Diseases and Conditions, Gammaproteobacteria, Genetics, Gram-Negative Bacteria, Gram-Negative Facultatively Anaerobic Rods, Proteobacteria, Salmonella, Salmonella enterica Keywords: Jalisco; Mexico; North and Central America; Enterobacteriaceae; Foodborne Diseases and Conditions; Gammaproteobacteria; Genetics; Gram-Negative Bacteria; Gram-Negative Facultatively Anaerobic Rods; Proteobacteria; Salmonella; Salmonella enterica EN Jalisco Mexico North and Central America Enterobacteriaceae Foodborne Diseases and Conditions Gammaproteobacteria Genetics Gram-Negative Bacteria Gram-Negative Facultatively Anaerobic Rods Proteobacteria Salmonella Salmonella enterica 2023 MAR 16 (NewsRx) -- By a News Reporter-Staff News Editor at Food Weekly News -- New research on Gram-Negative Bacteria - Salmonella enterica is the subject of a report. [Extracted from the article]

Additionally, western blot assays for some proteins of the VEGF-A/VEGFR-2 signaling pathway (VEGF-A, VEGFR-2, PI3K, Akt, and iNOS) were carried out. Keywords: Jalisco; Mexico; North and Central America; Angiogenic Proteins; Brain Research; Central Nervous System; Cerebrum; Frontal Lobe; Glutamates; Glutamic Acid; Growth Factor Receptors; Intercellular Signaling Peptides and Proteins; Membrane Proteins; Motor Cortex; Phosphotransferases; Prosencephalon; Protein Kinases; Receptor Protein-Tyrosine Kinases; Risk and Prevention; Telencephalon; VEGF; Vascular Endothelial Growth Factors EN Jalisco Mexico North and Central America Angiogenic Proteins Brain Research Central Nervous System Cerebrum Frontal Lobe Glutamates Glutamic Acid Growth Factor Receptors Intercellular Signaling Peptides and Proteins Membrane Proteins Motor Cortex Phosphotransferases Prosencephalon Protein Kinases Receptor Protein-Tyrosine Kinases Risk and Prevention Telencephalon VEGF Vascular Endothelial Growth Factors 2023 MAR 6 (NewsRx) -- By a News Reporter-Staff News Editor at Pain & Central Nervous System Week -- Current study results on Membrane Proteins - Receptor Protein-Tyrosine Kinases have been published. [Extracted from the article]

Keywords: Jalisco; Mexico; North and Central America; Autoimmune Diseases and Conditions; Autoimmune Diseases and Conditions of the Nervous System; CNS Demyelinating Autoimmune Disease; Demyelinating Diseases and Conditions; Health and Medicine; Immune System Diseases and Conditions; Multiple Sclerosis; Neuroimmunology; Neurology; Relapsing-Remitting Multiple Sclerosis EN Jalisco Mexico North and Central America Autoimmune Diseases and Conditions Autoimmune Diseases and Conditions of the Nervous System CNS Demyelinating Autoimmune Disease Demyelinating Diseases and Conditions Health and Medicine Immune System Diseases and Conditions Multiple Sclerosis Neuroimmunology Neurology Relapsing-Remitting Multiple Sclerosis 2023 FEB 27 (NewsRx) -- By a News Reporter-Staff News Editor at Pain & Central Nervous System Week -- A new study on Autoimmune Diseases and Conditions - Relapsing-Remitting Multiple Sclerosis is now available. To determine PTN serum levels in patients with RRMS, treated with Glatiramer acetate (GA) or Interferon-beta (IFN-beta), as well as in non-treated patients and healthy controls as a first attempt to explore PTN in RRMS. [Extracted from the article]

Jalisco, Mexico, North and Central America, Immunology, Blood Cells, Erythrocytes, Cell Research, Health and Medicine, Photochemistry and Photobiology, Chemistry, Mexican Social Security Institute Keywords: Mexican Social Security Institute; Jalisco; Mexico; North and Central America; Immunology; Blood Cells; Erythrocytes; Cell Research; Health and Medicine; Photochemistry and Photobiology; Chemistry EN Mexican Social Security Institute Jalisco Mexico North and Central America Immunology Blood Cells Erythrocytes Cell Research Health and Medicine Photochemistry and Photobiology Chemistry Research findings on photochemistry and photobiology are discussed in a new report. [Extracted from the article]

Jalisco, Mexico, North and Central America, Obesity Fitness and Wellness Keywords: Jalisco; Mexico; North and Central America; Obesity Fitness and Wellness EN Jalisco Mexico North and Central America Obesity Fitness and Wellness 2023 FEB 10 (NewsRx) -- By a News Reporter-Staff News Editor at Genomics & Genetics Weekly -- New research on Obesity, Fitness and Wellness is the subject of a report. [Extracted from the article]