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A recent study conducted by researchers at the University of Southern Florida has shed light on the role of a protein called BB0556 in Borrelia burgdorferi, the bacterium responsible for causing Lyme disease. The study found that BB0556 is a virulence factor that is essential for the bacterium's ability to infect mammals. The researchers discovered that BB0556 is highly expressed in infected mice tissues and plays a crucial role in the infection process. This research provides valuable insights into the mechanisms of Borrelia burgdorferi infection and could potentially lead to the development of new treatments for Lyme disease. [Extracted from the article]

A report from the Fred Hutchinson Cancer Research Center discusses new findings on Treponema denticola, a type of Gram-Negative Bacteria. The research highlights the role of oral spirochetes in periodontal disease and their presence in tumor specimens from patients with oral squamous cell carcinoma. The study focuses on T. denticola as a model organism for studying spirochete metabolic processes and interactions with other microbes. The researchers have developed new techniques, such as SyngenicDNA-based plasmids, to enhance the transformation efficiency and enable further examination of T. denticola physiology and behavior. [Extracted from the article]