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A recent study conducted by researchers at Johns Hopkins University in Baltimore, Maryland, has found that a specific gene mutation known as C9ORF72 is the most common inherited cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). This mutation leads to the production of toxic proteins that impair protein synthesis and cause neuronal dysfunction and degeneration. The researchers discovered that targeting a specific stress response pathway may be neuroprotective for patients with ALS/FTD caused by this gene mutation. This research provides valuable insights into potential therapeutic strategies for these neurodegenerative diseases. [Extracted from the article]