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The western Principal Cordillera consists of thick volcanic successions accumulated in an extensional basin and deformed in Early Neogene times during tectonic inversion of the basin. In the study region, key-layers are lacking and, for this reason, geometrical reconstructions are difficult. The main structure is a N-S-oriented syncline bounded by faults. Reconstructions using the fault-propagation fold and trishear models indicate that this structure is controlled by faults, a western (WF, cut-off angle ∼40-60°) and an eastern fault (EF, cut-off angle ∼20°). WF, the most important one, is interpreted as an inverted normal fault associated with basin inversion, whereas EF is interpreted as a short-cut related to WF. Shortening is 2-3 km (∼30%). [ABSTRACT FROM AUTHOR]

Introduction: Introduction: in Western societies, social networks are prominent sources of information and entertainment, widely accessed due to internet availability. While social networks offer health benefits, their impact varies across generations and populations. Concerns arise about their influence on mental health, with potential hindrance to social relationships. Social networks are recognized as contributors to eating disorders, influencing nutritional behaviors and impacting self-perception negatively. For this, the objective of present study was determining the association between the risk of eating disorders (ED) and the use of social networks in young adults in the Araucanía Region of Chile. Methods: a descriptive cross-sectional study was conducted on the young adult population. The subjects were recruited online through crucial social networks between November and December 2021. A self-reported online form was administered, asking for sociodemographic variables, social network use, and risk of eating disorders. The EAT-26 was applied for the latter variable. To determine the association between variables, each condition was dichotomized against the presence or absence of ED risk. Results: a total of 370 responses were collected, representing females (62.7 %) primarily from the 20-28 age group (79.5 %) and from the university student group (54.9 %); 12.9 % of the sample were at risk of ED. The variables associated with a higher risk of an eating disorder were being female (p = 0.001), preference for Twitter (p = 0.017), interest in food influencers (p = 0.008), and perceived frequency of advertising (p = 0.007). Conclusion: in this sample, there is an association between the use of social networks and the risk of ED, but this depends mainly on the social network used and exposure/preference of food-related content.

Obesity is a major worldwide health threat. It is characterized by an abnormal adipose tissue overgrowth together with increased monocytes infiltration, causing inflammation and oxidative stress, events associated with several illnesses. Investigations have focused on the benefits of native fruit consumption, claiming these to be natural sources of bioactive compounds with antioxidant and anti-inflammatory characteristics. It has been widely stated that berries are a source of the most antioxidant compounds, and, thus, seem highly promising to endure research efforts on these vegetal matrices. The present article describes botanical, chemical and biomedical features of the Chilean native berries, Aristotelia chilensis, Ugni molinae, and Berberis microphylla. This work aims to potentiate incoming research focused on the search for novel treatments for first-order diseases with these particular plant sources.

Obesity is characterized by an increase in the infiltration of monocytes into the adipose tissue, causing an inflammatory condition associated with, for example, the development of insulin resistance. Thus, anti-inflammatory-based treatments could emerge as a novel and interesting approach. It has been reported that Chilean native fruits maqui (Aristotelia chilensis) and calafate (Berberis microphylla) present high contents of polyphenols, which are known for their antioxidant and anti-inflammatory properties. The aim of this study was to evaluate the ability of extracts of these fruits to block the pathogenic interaction between adipocytes and macrophages in vitro and to compare its effect with blueberry (Vaccinium corymbosum) extract treatment, which has been already described to possess several biomedical benefits. RAW264.7 macrophages were treated with 5 μg/mL lipopolysaccharides (LPS), with conditioned media (CM) from fully differentiated 3T3-L1 adipocytes, or in a coculture (CC) with 3T3-L1 adipocytes, in the presence or absence of 100 μM [total polyphenolic content] of each extract for 24 h. The gene expression and secretion profile of several inflammatory markers were evaluated. Nitric oxide secretion induced by LPS, CM, and CC was reduced by the presence of maqui (-12.2%, -45.6%, and -14.7%, respectively) and calafate (-27.6%, -43.9%, and -11.8%, respectively) extracts. Gene expression of inducible nitric oxide synthase and TNF-α was inhibited and of IL-10 was induced by maqui and calafate extract incubation. In conclusion, the extracts of these fruits present important inhibitory-like features over the inflammatory response of the interaction between adipocytes and macrophages, comprising a potential therapeutic tool against comorbidities associated with obesity development.