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Therefore, the mechanisms that promote interactions between metastatic tumour cells and activated tumour-associated lymphatic endothelium in primary tumours and draining lymph nodes should be investigated in more detail to prevent and treat EMPD. Extramammary Paget's disease (EMPD) is a rare tumour presenting with an erythematous spread in elderly patients, mainly in the genital region.[[1]] It is most common in Caucasian women, but in Asian populations, there is a male predominance.[[3]] Given the rarity of this disease, limited studies have reported the 5-year outcomes on the Chinese population; hence a comprehensive survival analysis on the Chinese mainland is still lacking. Additional prospective data are needed to clarify the characteristics of high-risk EMPD patients and to further identify better and more effective superior management approaches to recurrent and potential tumour metastasis. [Extracted from the article]

Photodynamic Therapy with 5-aminolevulinic acid (ALA-PDT) has been widely applied in the treatment of skin diseases in China. To further standardize, guide, and promote the clinical applications of ALA-PDT in dermatology, the Chinese Society of Dermatology, Chinese Association of Rehabilitation Dermatology, Photomedicine Therapeutic Equipment Group of Committee on Skin Disease, and Cosmetic Dermatology of China Association of Medical Equipment invited relevant experts engaged in ALA-PDT to revise and update the first edition of "Clinical application of 5-aminolevulinic acid-based photodynamic therapy: an expert consensus statement" and establish a more current edition, to provide an updated reference for Chinese dermatologists in clinical practice. In the guideline, the expert group reached consensus opinions on ALA-PDT with regard to mechanisms of action, therapeutic protocol, clinical applications, adverse reactions and countermeasures, precautions, care, and evaluation of efficacy., (Copyright © 2021. Published by Elsevier B.V.)

Health professions preventing and controlling Coronavirus Disease 2019 are prone to skin and mucous membrane injury, which may cause acute and chronic dermatitis, secondary infection and aggravation of underlying skin diseases. This is a consensus of Chinese experts on protective measures and advice on hand-cleaning- and medical-glove-related hand protection, mask- and goggles-related face protection, UV-related protection, eye protection, nasal and oral mucosa protection, outer ear, and hair protection. It is necessary to strictly follow standards of wearing protective equipment and specification of sterilizing and cleaning. Insufficient and excessive protection will have adverse effects on the skin and mucous membrane barrier. At the same time, using moisturizing products is highly recommended to achieve better protection., (© 2020 Wiley Periodicals, Inc.)