1. Klebsiella pneumoniae invasive liver abscess syndrome with purulent meningitis and septic shock: A case from mainland China.
- Author
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Qian Y, Wong CC, Lai SC, Lin ZH, Zheng WL, Zhao H, Pan KH, Chen SJ, and Si JM
- Subjects
- Anti-Bacterial Agents therapeutic use, Bacteriological Techniques, China, Disease Progression, Drainage, Fatal Outcome, Female, Humans, Klebsiella Infections diagnosis, Klebsiella Infections therapy, Klebsiella pneumoniae drug effects, Klebsiella pneumoniae isolation & purification, Liver Abscess diagnosis, Liver Abscess therapy, Meningitis, Bacterial diagnosis, Meningitis, Bacterial therapy, Middle Aged, Shock, Septic diagnosis, Shock, Septic therapy, Tomography, X-Ray Computed, Treatment Outcome, Klebsiella Infections microbiology, Klebsiella pneumoniae pathogenicity, Liver Abscess microbiology, Meningitis, Bacterial microbiology, Shock, Septic microbiology
- Abstract
We present a rare case of invasive liver abscess syndrome due to Klebsiella pneumoniae (K. pneumoniae) with metastatic meningitis and septic shock. A previously healthy, 55-year-old female patient developed fever, liver abscess, septic shock, purulent meningitis and metastatic hydrocephalus. Upon admission, the clinical manifestations, laboratory and imaging examinations were compatible with a diagnosis of K. pneumoniae primary liver abscess. Her distal metastasis infection involved meningitis and hydrocephalus, which could flare abruptly and be life threatening. Even with early adequate drainage and antibiotic therapy, the patient's condition deteriorated and she ultimately died. To the best of our knowledge, this is the first case of K. pneumoniae invasive liver abscess syndrome with septic meningitis reported in mainland China. Our findings reflect the need for a better understanding of the epidemiology, risk factors, complications, comorbid medical conditions and treatment of this disease.
- Published
- 2016
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