1. Evaluation of coronavirus in tears and conjunctival secretions of patients with SARS-CoV-2 infection.
- Author
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Xia J, Tong J, Liu M, Shen Y, and Guo D
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Betacoronavirus isolation & purification, Betacoronavirus pathogenicity, Bodily Secretions chemistry, Bodily Secretions virology, COVID-19, COVID-19 Testing, China, Clinical Laboratory Techniques methods, Conjunctiva chemistry, Coronavirus Infections virology, Female, Humans, Male, Middle Aged, Pandemics, Pneumonia, Viral virology, Prospective Studies, Reverse Transcriptase Polymerase Chain Reaction, SARS-CoV-2, Tears chemistry, Betacoronavirus genetics, Conjunctiva virology, Coronavirus Infections diagnosis, Pneumonia, Viral diagnosis, Tears virology
- Abstract
Objective: This study aimed to assess the presence of novel coronavirus in tears and conjunctival secretions of SARS-CoV-2-infected patients., Methods: A prospective interventional case series study was performed, and 30 confirmed novel coronavirus pneumonia (NCP) patients were selected at the First Affiliated Hospital of Zhejiang University from 26 January 2020 to 9 February 2020. At an interval of 2 to 3 days, tear and conjunctival secretions were collected twice with disposable sampling swabs for reverse-transcription polymerase chain reaction (RT-PCR) assay., Results: Twenty-one common-type and nine severe-type NCP patients were enrolled. Two samples of tear and conjunctival secretions were obtained from the only one patient with conjunctivitis yielded positive RT-PCR results. Fifty-eight samples from other patents were all negative., Conclusion: We speculate that SARS-CoV-2 may be detected in the tears and conjunctival secretions in NCP patients with conjunctivitis., (© 2020 Wiley Periodicals, Inc.)
- Published
- 2020
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