1. Endoscopic ultrasonography for staging of T1a and T1b esophageal squamous cell carcinoma.
- Author
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He LJ, Shan HB, Luo GY, Li Y, Zhang R, Gao XY, Wang GB, Lin SY, Xu GL, and Li JJ
- Subjects
- Adult, Aged, Biopsy, Carcinoma, Squamous Cell pathology, Chi-Square Distribution, China, Early Detection of Cancer, Esophageal Neoplasms pathology, Esophageal Squamous Cell Carcinoma, Female, Humans, Male, Middle Aged, Multivariate Analysis, Odds Ratio, Predictive Value of Tests, Proportional Hazards Models, Reproducibility of Results, Retrospective Studies, Carcinoma, Squamous Cell diagnostic imaging, Endosonography, Esophageal Neoplasms diagnostic imaging, Neoplasm Staging methods
- Abstract
Aim: To investigate the accuracy of Endoscopic ultrasound (EUS) in staging and sub-staging T1a and T1b esophageal squamous cell carcinoma (ESCC)., Methods: A retrospective analysis involving 72 patients with pathologically confirmed T1a or T1b ESCC, was undertaken between January 2005 and December 2011 in Sun Yat-sen University Cancer Center. The accuracy and efficiency of EUS for detecting stages T1a and T1b ESCC were examined., Results: The overall accuracy of EUS for detecting stage T1a or T1b ESCC was 70.8% (51/72), and the sensitivity was 74.3%. 77.8% (7/9) of lesions originated in the upper thoracic region, 73.1% (38/52) in the mid-thoracic region and 72.7% (8/11) in the lower thoracic region. Multivariate analysis revealed that the diagnostic accuracy of EUS was closely related to lesion length (F = 4.984, P = 0.029)., Conclusion: EUS demonstrated median degree of accuracy for distinguishing between stages T1a and T1b ESCC. Therefore, it is necessary to improve EUS for staging early ESCC.
- Published
- 2014
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