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Stimulated reservoir volume (SRV) which is generated by horizontal drilling with multistage hydraulic fracturing governs the production in the shale gas reservoirs. Although microseismic data has been used to estimate the SRV, it is high-priced and sometimes overestimated. Additionally, the effect of stress sensitivity on SRV is not considered in abnormal overpressure areas. Thus, the objective of this work is to characterize subsurface fracture networks with stress sensitivity of permeability through the shale gas well production data of the early flowback stage. The flowback regions are first identified with the flowback data of two shale gas wells in South China. Then, we measured the permeability stress sensitivity of the core after fracturing, coupled to the dynamic relative permeability (DRP) calculation to obtain an accurate and simple DRP curve. After that, a comprehensive model is built considering dynamic two-phase relative permeability function and stress sensitivity. Finally, we compared the calculated results with the microseismic data. The results show that the proposed model could reasonably predict the SRV using the flowback data after fracturing. Additionally, compared with the microseismic data, the stress sensitivity should be included, especially in the abnormal overpressure block. It is believed that this mathematical model is accurate and useful. The work provides an efficient approach to estimate stimulated reservoir volume in the shale gas reservoirs. [ABSTRACT FROM AUTHOR]

Combining horizontal drilling with hydraulic fracturing has become a well-established technique to improve well productivity in tight oil reservoirs. The existence of micro-fractures in these reservoirs affects the fluid flow process as well as the productivity. However, current models for evaluating the well performance of fractured horizontal wells containing micro-fractures lack accuracy. Hence, the objective of this study is to build an efficient model to analyze well productivity, considering the effects of micro-fractures. A novel flow model for multi-fractured horizontal wells was established, considering the effect of micro-fractures on the fluid flow. Subsequently, we built a reservoir model based on the typical fracture and fluid properties of a tight oil block in the Daqing oil field, China. Good agreement between the prediction results and field data was obtained, indicating that the effect of micro-fractures on well productivity cannot be neglected. Further study reveals that micro-fractures essentially function as a joint connecting reservoir matrix and have a persistent impact on well productivity. Micro-fractures can promote well productivity; however, if the value of micro-fracture permeability increases, this promotional effect will slow down. Well productivity can be considerably improved as an increase in micro-fracture percentage. Finally, a series of sensitivity studies were conducted to identify the effects of critical parameters on well productivity. Results show that reservoir permeability significantly influences well productivity, followed by reservoir effective thickness, micro-fracture percentage, fracture number, hydraulic fracture half-length. Pressure sensitivity coefficient, threshold pressure gradient and micro-fracture permeability have the least effect on well productivity. This work provides a sophisticated and efficient tool to evaluate the productivity of multi-fractured horizontal wells in tight oil reservoirs with micro-fractures. • A comprehensive productivity prediction model considering micro-fracture is proposed in tight oil reservoirs. • Validation study illustrates that this proposed model can accurately and efficiently evaluate well productivity. • Sensitivity studies show that micro-fracture is a critical parameter of well performance. [ABSTRACT FROM AUTHOR]

Chinese yam is a traditional Chinese medicine that has a long history of medicinal and edible usage in China and is widely utilised in food, medicine, animal husbandry, and other industries. Chinese yam polysaccharides (CYPs) are among the main active components of Chinese yam. In recent decades, CYPs have received considerable attention because of their remarkable biological activities, such as immunomodulatory, antitumour, hypoglycaemic, hypolipidaemic, antioxidative, anti-inflammatory, and bacteriostatic effects. The structure and chemical alterations of polysaccharides are the main factors affecting their biological activities. CYPs are potential drug carriers owing to their excellent biodegradability and biocompatibility. There is a considerable amount of research on CYPs; however, a systematic summary is lacking. This review summarises the structural characteristics, derivative synthesis, biological activities, and their usage as drug carriers, providing a basis for future research, development, and application of CYPs. [ABSTRACT FROM AUTHOR]