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The article presents a study related to association of ACP1 gene polymorphisms and coronary artery disease (CAD) in northeast Chinese population. The findings include no significant difference in the ACP1 allele frequencies when compared to the distribution of the ACP1 alleles between CAD patients and control subjects, genotype of genetic algorithm (GA) may be a protective genotype against CAD, and genotype of GA polymorphism in ACP1 linked to reduced risk of CAD in Chinese population.