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Background: The authors compare the effectiveness and safety of endovascular treatment (EVT) versus best medical management (BMM) in strokes attributable to acute basilar artery occlusion (BAO).Methods: The present analysis was based on the ongoing, prospective, multicenter ATTENTION (Endovascular Treatment for Acute Basilar Artery Occlusion) trial registry in China. Our analytic sample comprised 2134 patients recruited at 48 sites between 2017 and 2021 and included 462 patients who received BMM and 1672 patients who received EVT. We performed an inversed probability of treatment weighting analysis. Qualifying patients had to present within 24 hours of estimated BAO. The primary clinical outcome was favorable functional outcome (modified Rankin Scale score, 0-3) at 90 days. We also performed a sensitivity analysis with the propensity score matching-based and the instrumental variable-based analysis.Results: In our primary analysis using the inversed probability of treatment weighting-based analysis, there was a significantly higher rate of favorable outcome at 90 days among EVT patients compared with BMM-treated patients (adjusted relative risk, 1.42 [95% CI, 1.19-1.65]; absolute risk difference, 11.8% [95% CI, 6.9-16.7]). The mortality was significantly lower (adjusted relative risk, 0.78 [95% CI, 0.69-0.88]; absolute risk difference, -10.3% [95% CI, -15.8 to -4.9]) in patients undergoing EVT. Results were generally consistent across the secondary end points. Similar associations were seen in the propensity score matching-based and instrumental variable-based analysis.Conclusions: In this real-world study, EVT was associated with significantly better functional outcomes and survival at 90 days. Well-designed randomized studies comparing EVT with BMM in the acute BAO are needed.Registration: URL: www.chictr.org.cn; Unique identifier: ChiCTR2000041117. [ABSTRACT FROM AUTHOR]

• Water and energy input in crop production as a basis for agricultural development. • Irrigation water and fertilisers are important factors in generating CO 2 emissions. • Optimization model for sustainable agricultural development is established. • Agricultural resources utilization efficiency is improved. Agricultural sustainability is substantially influenced by the water-energy-food (WEF) nexus and CO 2 emissions. However, previous research has minimally focused on the impacts of agricultural CO 2 emissions on sustainable agricultural management. Therefore, to address this research gap, based on the water-energy-food nexus index (WEFNI) and CO 2 emissions, this study constructs a multi-objective nonlinear optimisation method for sustainable agricultural management. The crop production and emissions reduction potential under various optimisation schemes were analysed using the major crops (rice, wheat, maize, and cotton) in the Tarim River Basin (TRB), the largest inland river in China, as a test case.Cotton, as a high water- and energy-consuming crop, had a lower water and energy mass productivity than other crops. Improvements in irrigation efficiency and mechanisation in the TRB have had major effects on water conversation and carbon reduction. The intensity of agricultural CO 2 emissions in the basin showed a decreasing trend from 1990 to 2020, with wheat CO 2 emissions decreasing only slightly (-10860.92 kg CO 2 eq/ha). In the optimal scenario that ensures maximum WEFNI and minimum agricultural CO 2 emissions, the irrigation efficiency increases to 0.59, and the crop area for wheat and maize increases substantially, indicating that the TRB still exhibits potential for crop production. Most importantly, the Dina would save 4250.52 × 104 m3 of water resources, increase the area of maize cultivation by 1249.84 ha, increase food production by 0.68 × 104 tonnes, and reduce energy consumption and agricultural CO 2 emissions by 1297.52 × 104 MJ and 890.25 × 104 kg CO 2 eq, respectively. The optimisation model had obvious effects on water saving and agricultural CO 2 reduction and may represent a vital component in completing the "14th Five-Year Plan" of the basin and promoting the sustainable agricultural development. [ABSTRACT FROM AUTHOR]

As a key component in mitigating global warming and achieving sustainable development strategies, wind power has received widespread attention and support from governments around the world. Numerous countries are engineering ambitious programs to map and project the mitigation potential of wind energy expansion to combat future global warming. Here, using the global installed wind capacity data, we identity that a total of 837 GW of wind energy installed capacity (WEIC) in 31 countries generated about 2186 TWh of electricity, that is 1311 Mt of CO 2 mitigation, in 2021. Considering power mix transformation, wind power could account for more than 30% of total global electricity generation by the mid-21st century, when many countries expect to realize carbon neutrality, and could reduce CO 2 emission up to 14871 Mt by 2050 and 32864 Mt by 2100. Meanwhile, the global phenomenon of the future southward shift of wind energy resources makes the wind energy development in low-latitude countries, such as Brazil, Vietnam, and Central African, more confident. Combined with the Shared Socio-economic Pathways (SSPs), we find that the mitigation benefits of wind energy expansion are significant and will directly reduce global warming by up to 0.64 °C by the end of the century (NZE deployment scenario, SSP3-7.0). For China and the United States, the share of renewable energy will reach 78% and 84% by 2050 (APS scenario) and the cumulative climate mitigation by wind power will be 0.12 °C and 0.11 °C during 2020–2100, respectively. The findings strongly support the development and practice of global climate mitigation energy solutions. • This study quantifies wind energy's impact on CO 2 and temperatures reduction. • Global wind energy can currently mitigate 1311 Mt CO 2 , up to 32864 Mt by 2100. • Wind energy expansion could mitigate global warming by up to 0.64 °C in 2100. • China and the U.S. lead global CO 2 reductions in wind power. [ABSTRACT FROM AUTHOR]

Reduced-activation ferritic-martensitic (RAFM) steel is considered as the primary candidate structural material for blankets of ITER, CFETR and DEMO. Several RAFMs have been developed in China (CN-RAFMs) such as CLAM, CLF-1, modified RAFMs and oxide dispersion strengthened RAFMs (ODS-RAFMs). The mechanical properties, irradiation behaviors, additive manufacturing and joining technologies of structural materials have been comprehensively studied. Qualifications of CN-RAFMs are on-going for ITER-TBM fabrication, with emphasis on material property databases and standardization. A new neutron irradiation program is being carried out for a series of fusion materials e.g. RAFMs and ODS-RAFMs with doses up to 40 dpa. Joining technologies (e.g. electron beam welding, tungsten inert gas welding, laser beam welding and diffusion welding, etc.) and advanced additive manufacturing are performed to overcome the big challenges of the blanket fabrication before ITER, CFETR and DEMO. The databases and standards for CLAM and CLF-1 were established respectively, and the specification and qualification of them are underway for ITER-TBM. In this paper, the latest development and strategy on fusion energy in China are briefly introduced, and the progresses of R&D activities on CN-RAFMs aiming for the engineering applications are reviewed. [ABSTRACT FROM AUTHOR]