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1. Genotyping of mitochondrial aldehyde dehydrogenase locus of Native American Indians.

Author

O'Dowd BF, Rothhammer F, and Israel Y

Subjects
Adult, Chile, China, Chromosome Mapping, Gene Amplification genetics, Hair enzymology, Humans, Japan, Aldehyde Dehydrogenase genetics, Cross-Cultural Comparison, Genotype, Indians, South American genetics, Isoenzymes genetics, Mitochondria enzymology
Abstract

Using the polymerase chain reaction to amplify genomic DNA from hair roots, we have examined the mitochondrial aldehyde dehydrogenase (ALDH2) genotypes of 28 individuals from the South American Mapuche Indians. We have determined that individuals from this population previously reported to lack (ALDH2) activity do not show the presence of the inactive (ALDH2(2] allele frequently found in Orientals.

Published
1990
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