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Novel prediction methods using artificial intelligence have been developed to improve the identification, discovery, and utilization of new types of mineral resources at new depths or using new technologies. However, most artificial intelligence methods require large training data sets that are often unavailable for mineralization prediction models, leading to inaccuracies. To address this issue, we developed a semi‐supervised machine‐learning method to identify metallogenic anomalies using the density‐based spatial clustering of applications with noise method and autoencoder. The outputs of this method show irregularity in distributions inferred from geological, geochemical, and hyperspectral remote sensing data that match known mineralization locations. We focus on the Daqiao mining area of Gansu Province in China to show that the model predictions are highly consistent with known deposits of the Yinmahe and Daqiao gold mines, and two new prospecting areas have been highlighted for further field confirmation. The accuracy of this semi‐supervised learning method was verified by an interdisciplinary intelligent analysis, showing that this method could have wide‐reaching applications for improving regional geological surveys. Plain Language Summary: Mineral resources are irreplaceable and necessary for modernization. Novel prediction methods using artificial intelligence have been developed to improve the prediction of mineral resources. However, the training data sets are still a big problem for the artificial intelligence methods used in this application. To solve this issue, we developed a semi‐supervised machine‐learning method to identify metallogenic anomalies using the DBSCAN and autoencoder. The accuracy of this method was verified by an interdisciplinary intelligent analysis, showing that this method could have wide‐reaching applications for improving regional geological surveys. Key Points: A new artificial intelligence technology to analyze multivariate data for ore prospecting and predictionThe prediction results show that ore bodies in the Daqiao area are controlled by the large fault structureThe improvement and new applications of remote sensing image data to synthesize geological and geochemical data for ore‐forming anomalies [ABSTRACT FROM AUTHOR]

[Display omitted] • In the case of a small number of known deposits and mineral occurrences, the prospecting prediction model based on the Siamese network can extract effective features without relying on prior knowledge to realize supervised prospecting prediction. • On the basis of sliding window data enhancement, this paper generates paired sample data sets by randomly combining deposit samples and non-deposit samples, which can further enhance the data and improve the generalization ability and prediction accuracy of the model to a certain extent. • Compared with the prediction results of the weight of evidence method and the convolutional neural network, the prediction results of the Siamese network are better, and 7 new gold prospecting areas have been discovered in Zhangjiakou, Hebei Province, China. Supervised neural networks constitute an important research area for the intelligent prediction of locations for prospecting mineral deposits. Accurate training of a supervised neural network requires many training samples, something that is often difficult to obtain. This paper reports the use of geological, geochemical, and geophysical data by a Siamese network to overcome the problem of insufficient training samples, and implements a supervised deep learning prospecting prediction method based on the Siamese network. Intelligent prediction for gold deposits prospecting is carried out for the Chongli mineral concentrate area in Zhangjiakou, Hebei Province, China, and compared with the weight of evidence method and convolutional neural network model. The results show that:(a) the performance of the Siamese network model is no less than that of the convolutional neural network (CNN) model and better than that of the weight of evidence (WOE) method; (b) the gold prospective areas differentiated by the established models are strongly consistent with geological and metallogenic characteristics in the study area. This study suggests Siamese network model as an effective mineral prospectivity modeling tool. This method is also suitable for prospecting prediction using geoscience data in other areas. [ABSTRACT FROM AUTHOR]