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[Display omitted] • Sixteen aroma compounds were identified as key compounds to distinguish FHDC and TGY. • Twenty compounds were selected as typical markers for the 10 FHDC fragrance types. • Benzyl nitrile and phenylethyl alcohol in RG are key markers to distinguish others. • β -Pinene in JH, and α -phellandrene in ZL are key aroma markers to distinguish others. Fenghuang Dancong tea (FHDC), a famous oolong tea originating from Guangdong Province in China, is known for its rich and unique fragrance. Nevertheless, the identification of the key aroma compounds with the difference fragrance types of FHDC remains uncertain. In order to characteristic the volatile components in different fragrance types of FHDC, 10 well-known fragrance types of FHDC and Tieguanyin (TGY) as a control were analyzed by headspace solid-phase microextraction (HS-SPME) coupled with gas chromatography mass spectrometry (GC–MS). Results indicated that 172 volatile compounds were identified as common volatile compounds among all the tea samples. A total of 16 compounds were identified as key compounds that could be used to distinguish between FHDC and TGY. Among the 10 FHDC fragrance types, indole, hotrienol, benzyl nitrile, and jasmine lactone were found to be the most abundant compounds. Despite the presence of certain similarities in aroma components, each type exhibits unique fragrance characteristics as a result of variation in compound composition content and proportion. Furthermore, using statistical and odor activity value analysis, 20 aroma-active compounds were recognized as potential characteristic markers accountable for the diverse fragrance types of FHDC. This research enhances our comprehension of the various fragrance types of FHDC and provides reference values for their rapid identification in the market. [ABSTRACT FROM AUTHOR]

Objective To compare three-dimensional (3D) and two-dimensional (2D) speckle tracking echocardiography ( STE) techniques in the assessment of left ventricular function and myocardial infarct size ( MIS). Methods Thirty-two patients diagnosed with ST elevation myocardial infarction and 18 healthy control patients underwent 2D echocardiography, 3D echocardiography, and single photon emission computed tomography ( SPECT). 3D left ventricular global area strain ( GAS), 2D and 3D global longitudinal strain ( GLS), global radial strain ( GRS) as well as global circumferential strain ( GCS) were analyzed to correlate with myocardial infarct size detected by SPECT. 2D and 3D left ventricular ejection fraction ( LVEF) as well as 2D and 3D wall motion score index ( WMSI) also were measured using conventional echocardiography. Results The 2D- GLS values were significantly higher than that of 3D- GLS, while 2D- GCS and GRS were significantly lower than 3D- GCS and GRS, respectively. However, no significant differences in LVEF and WMSI could be observed between 2D and 3D echocardiography. Myocardial strain indices, LVEF, and WMSI using 2D and 3D echocardiography also had good correlations with MIS as measured by SPECT. ROC curve analysis showed that the 3D and 2D myocardial indices, LVEF, and WMSI could distinguish between small and large MIS, while 2D- GLS had the highest AUC. Conclusion The 2D and 3D myocardial strain indices correlated well with MIS by SPECT. Among them, the 2D- GLS showed the highest diagnostic value, while 3D- GRS and GCS had better diagnostic value than 2D- GRS and GCS. [ABSTRACT FROM AUTHOR]

Aim: Examine the levels of variables and explore drivers associated with shared decision-making attitudes among newly graduated nurses., Design: This was a descriptive and cross-sectional study., Methods: From August 2022 to October 2022, a cross-section of 216 newly graduated nurses from four comprehensive A-level hospitals in northern China was recruited using convenience sampling. Newly graduated nurses are generally defined as nurses with a service period of six months to one year. Data were collected using an online questionnaire support platform, including the Nursing Shared Decision-Making Attitude scale, Jefferson scale of Empathy-Health profession students and the Health Sciences Evidence-Based Practice questionnaire. All data were analysed descriptively, and correlational analysis and hierarchical regression were used to make identical connections between variables., Results: Newly graduated nurses supported shared decision-making. Perceptions of shared decision-making were correlated with the experiences of empathy and evidence-based practice. Additionally, perspective-taking of empathy and beliefs, and the ability to search for and apply existing scientific findings of evidence-based practice had a significant impact on more positive attitudes., Conclusion: The survey showed that acceptance of shared decision-making was positive among newly graduated nurses. Clinical nursing managers and teachers should pay attention to cultivating the evidence-based practice and empathy of newly graduated nurses to adopt an optimistic attitude towards shared decision-making in the long term., Impact: The survey addresses attitudes of shared decision-making among newly graduated nurses and determines whether empathy and evidence-based practice has an impact on it. The main finding is that newly graduated nurses have an optimistic outlook on the implementation of shared decision-making. This survey showed that empathy and evidence-based practice competencies are associated with shared decision-making attitudes among newly graduated nurses. The results of this survey have an impact on educational institutions and hospitals in the form of recommendations. Several training programmes on empathy and evidence-based practice can help adopt the shared decision-making attitudes of newly graduated nurses., Patient or Public Contribution: No patient or public contribution., (© 2024 John Wiley & Sons Ltd.)

Infertility has a detrimental impact on the sexual function of involuntarily childless couples. However, the effect of male sexual function on female partner's sexual function in infertile couples remains unknown. In order to explore the association between these couples' sexual function, 324 consecutive couples with infertility and 326 female-age-matched fertile couples were enrolled in this study. The female sexual function index (FSFI) and sexual history were evaluated in female partners. In addition to the international index of erectile function-15 (IIEF-15) and sexual history, self-reported intravaginal ejaculation latency time was evaluated in male partners. The demographics and depression status of couples were also recorded. We observed a higher occurrence of female sexual dysfunction (FSD) in infertile females than in fertile females (58.6% vs. 50.3%, p = 0.033). FSD was associated with a number of risk variables, including partner's erectile dysfunction (ED), depression and sexual frequency. The overall FSFI score was positively associated with the IIEF-15 score (r = 0.347, p < 0.001). Besides, six FSFI domains were positively correlated with five IIEF-15 domains (p < 0.05). In conclusion, it is critical to assess and address FSD as well as the sexual problems in male partners in infertile couples., (© 2022 Wiley-VCH GmbH.)

Background: During the coronavirus disease 2019 (COVID-19) epidemic, tumor patients and their families might suffer from greater psychological stress as a result of anxiety or other psychological disorders. We conducted an online study during the epidemic to explore the mental state of tumor patients and their families during this extraordinary time., Methods: A cross-sectional survey was carried out. Questionnaires were distributed through the WeChat "Questionnaire Star" network. The snowball sampling technique was adopted and further promoted by subjects who had completed the questionnaire., Results: A total of 1,030 valid questionnaires were collected. There were 609 (59.13%) tumor patients and 421 (40.87%) family members. One hundred and fifty-six (15.15%) subjects had anxiety, among which 65 (6.31%) had moderate to severe anxiety. Single-factor analysis indicated that age (>60 years old), the farmer occupation, and a high sleep disorder assessment score were risk factors for anxiety, while the latter two might also be independent risk factors, as suggested by multi-factor analysis. Infrequent contact with doctors was an independent risk factor for cancer patients, while uninterrupted anti-tumor therapy was an independent protective factor. 40.19% of the subjects expressed a need for psychosocial support during the COVID-19 period., Conclusions: The COVID-19 outbreak resulted in tumor patients and their relatives experiencing greater psychological pressure than usual, and patients were more worried about anti-tumor treatment and disease progression impacted by the epidemic. Both groups had a significant need for psychosocial help.

Camellia kucha (Chang et Wang) Chang is a special tea in China, which is extremely bitter but beneficial for human health. However, there are no systematic studies on Kucha metabolites, especially those associated with bitterness. In this study, a non-targeted metabolomics approach based on UHPLC-LTQ-Orbitrap-MS was applied to comprehensively profile the characteristic metabolites of two Kucha cultivars by comparison with three common tea cultivars. A total of 90 differential metabolites were identified. Among them, eight key metabolites (theacrine, 2,4-dimethyl-1H-indole, EGCG, dihydrokaempferol, panasenoside, 3-cresotinic acid, 3-methylglutaconic acid, and L-histidine) were more abundant in Kucha than in the controls, most of which were positively correlated with bitterness. Furthermore, quantitative analysis of some important catechins and alkaloids by HPLC implied absolutely higher concentrations of EGCG and theacrine in Kucha, which was similar to the metabolomics results. These results will be contribute to future research on the bitter and nutritional properties of Kucha., (Copyright © 2020 Elsevier Ltd. All rights reserved.)