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Electrocatalytic CO2 reduction is regarded as a green and promising technology because it can convert carbon dioxide into value-added fuel or chemicals in a flexible and sustainable way. This research aimed to comprehensively analyze the research hotspots and trends in the field of CO2 electroreduction from 2005 to 2022 using bibliometric methods based on the core database of Web of Science. The results showed that 4546 papers on CO2 electroreduction were retrieved from 2005 to 2022, with a clear increasing trend. The research direction was diversified, involving multiple disciplines, and it is a comprehensive research field. ACS Catalysis is the journal with the largest number of articles. China is the country with the largest number of documents and has made significant contributions to the development and progress of this field. Copper-based catalysts are still the research focus in recent years. It is of great practical significance to develop copper-based catalysts with high efficiency, low cost, high stability, and high selectivity for the preparation of C1 products. [ABSTRACT FROM AUTHOR]

To survey the epidemiological characteristics and clinical features on epilepsy in eight ethnic groups in Yunnan province of China. Methodes The investigation was based on the WHO questionnaire and ICBERG screening questionnaire. This study was performed through random cluster sampling and door-to-door survey. Results A total of 76,302 individuals from eight ethnic groups were surveyed. The crude prevalence of epilepsy ranged from 1.2/1000 to 6.5/1000 in the eight ethnic groups, and the age-adjusted prevalence of epilepsy was from 2.1/1000 to 7.3/1000. The prevalence of active epilepsy varied from 1.0/1000 to 5.2/1000 in the eight ethnic groups, and the age-adjusted prevalence of active epilepsy was from 1.8/1000 to 6.7/1000. The age peak for seizures was below twenty, the patients of 61.1%-95.0% suffered from generalized seizures and 5%-21.2% had partial seizures. More than 60% of the cases in five ethnic groups, and the frequency of seizures were more than 10 events per year. More than 50% in other three ethnic groups, and the seizures had occurred less than 10 events per year. The treatment gap for active epilepsy ranged from 43.7% to 100.0% among the eight ethnic groups, while the natural remission rate varied from 5.6% to 21.0%. Conclusion There were both disparity and similarity in the epidemiological and clinical features of epilepsy in different ethnic group communities. [ABSTRACT FROM AUTHOR]

Urban land expansion will influence aspects of economy and society, including the quality of the urban environment. This study aims to examine the impacts of urban land expansion in China on haze pollution under the fiscal decentralization system using the spatial Durbin model. Urban land expansion is measured using two dimensions of urban land expansion, namely, intensity and orderliness of the structure of urban land expansion. The results reveal that urban haze pollution in China exhibits significant positive spillover characteristics, which manifest as "high–high" and "low–low" characteristics of spatial agglomeration. In general, improving the expansion intensity of urban land and the orderly structure of urban land expansion can reduce haze pollution in local and surrounding areas. With the improvement of the degree of fiscal decentralization, the positive effect of an orderly urban land structure in reducing haze pollution will be weakened. The above-mentioned influences depict distinct heterogeneities at the levels of city size, type, and location. [Display omitted] • This study discusses the intensity and structure of urban land expansion. • This study uses the spatial Durbin model. • Improving the intensity and orderly structure of urban land expansion can reduce haze pollution. • Fiscal decentralization will weaken the positive effect of the orderly structure of urban land expansion on haze pollution. [ABSTRACT FROM AUTHOR]

The mobilization of internal phosphorus (P) plays a crucial role in transitioning nutrient limitations within lake ecosystems. While previous research has extensively examined P release in littoral zones influenced by fluctuating water levels, there is a paucity of studies addressing the implications of sustained water level rise in this context, particularly as it pertains to nutrient limitations in benthic algae. To address this gap, we conducted an integrated study in Qinghai Lake. In the field sampling and microcosm experiment, we found that P concentrations are elevated in areas subjected to short-term inundation compared to those enduring prolonged inundation, primarily due to the dissolution of sedimentary P fractions. The results of nutrient diffusing substrata (NDS) bioassays indicated that benthic algae in Qinghai Lake displayed either P limitation or NP co-limitation. The transition from P limitation to NP co-limitation suggested that internal P release may serve to ameliorate nutrient limitations in benthic algae. This phenomenon could potentially contribute to the proliferation of Cladophora in the littoral zones of Qinghai Lake, thereby posing long-term implications for the lake's aquatic ecosystem, particularly under conditions of sustained water level rise., (© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)

Background & Aims: We combined gene expression and metabolic profiling analyses to identify factors associated with outcomes of patients with hepatocellular carcinoma (HCC)., Methods: We compared metabolic and gene expression patterns between paired tumor and nontumor tissues from 30 patients with HCC, and validated the results using samples from 356 patients with HCC. A total of 469 metabolites were measured using liquid chromatography/mass spectrometry and gas chromatography/mass spectrometry. Metabolic and genomic data were integrated, and Kaplan-Meier and Cox proportional hazards analyses were used to associate specific patterns with patient outcomes. Associated factors were evaluated for their effects on cancer cells in vitro and tumor formation in nude mice., Results: We identified 28 metabolites and 169 genes associated with aggressive HCC. Lipid metabolites of stearoyl-CoA-desaturase (SCD) activity were associated with aberrant palmitate signaling in aggressive HCC samples. Expression of gene products associated with these metabolites, including SCD, were associated independently with survival times and tumor recurrence in the test and validation sets. Combined expression of SCD and α-fetoprotein were associated with outcomes of patients with early-stage HCC. Levels of monounsaturated palmitic acid, the product of SCD activity, were increased in aggressive HCCs; monounsaturated palmitic acid increased migration and invasion of cultured HCC cells and colony formation by HCC cells. HCC cells that expressed small interfering RNA against SCD had decreased cell migration and colony formation in culture and reduced tumorigenicity in mice., Conclusions: By using a combination of gene expression and metabolic profile analysis, we identified a lipogenic network that involves SCD and palmitate signaling and was associated with HCC progression and patient outcomes. The microarray platform and data have been submitted to the Gene Expression Omnibus public database at NCBI following MIAME guidelines. Accession numbers: GPL4700 (platform), and GSE6857 (samples)., (Copyright © 2013 AGA Institute. Published by Elsevier Inc. All rights reserved.)