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Based on panel data of 31 provinces in China from 2000 to 2019, this study explores the complex dynamic interaction between scientific and technological innovation, industrial structure transformation and economic development by building PVAR model. After GMM estimation, impulse response function analysis and variance decomposition analysis, the following conclusions are drawn: Technological innovation has a significant promoting effect on economic development, and economic development can also promote technological innovation; Technological innovation has a positive impact on industrial structure transformation, while industrial structure transformation has a slight negative impact on technological innovation; Economic development can lead to industrial structure transformation, but the impact of industrial structure transformation on economic development is not significant. [ABSTRACT FROM AUTHOR]

Background: Countries that aimed for eliminating the cases of COVID-19 with test-trace-isolate policy are found to have lower infections, deaths, and better economic performance, compared with those that opted for other mitigation strategies. However, the continuous evolution of new strains has raised the question of whether COVID-19 eradication is still possible given the limited public health response capacity and fatigue of the epidemic. We aim to investigate the mechanism of the Zero-COVID policy on outbreak containment, and to explore the possibility of eradication of Omicron transmission using the citywide test-trace-isolate (CTTI) strategy. Methods: We develop a compartmental model incorporating the CTTI Zero-COVID policy to understand how it contributes to the SARS-CoV-2 elimination. We employ our model to mimic the Delta outbreak in Fujian Province, China, from September 10 to October 9, 2021, and the Omicron outbreak in Jilin Province, China for the period from March 1 to April 1, 2022. Projections and sensitivity analyses were conducted using dynamical system and Latin Hypercube Sampling/ Partial Rank Correlation Coefficient (PRCC). Results: Calibration results of the model estimate the Fujian Delta outbreak can end in 30 (95% confidence interval CI: 28–33) days, after 10 (95% CI: 9–11) rounds of citywide testing. The emerging Jilin Omicron outbreak may achieve zero COVID cases in 50 (95% CI: 41–57) days if supported with sufficient public health resources and population compliance, which shows the effectiveness of the CTTI Zero-COVID policy. Conclusions: The CTTI policy shows the capacity for the eradication of the Delta outbreaks and also the Omicron outbreaks. Nonetheless, the implementation of radical CTTI is challenging, which requires routine monitoring for early detection, adequate testing capacity, efficient contact tracing, and high isolation compliance, which constrain its benefits in regions with limited resources. Moreover, these challenges become even more acute in the face of more contagious variants with a high proportion of asymptomatic cases. Hence, in regions where CTTI is not possible, personal protection, public health control measures, and vaccination are indispensable for mitigating and exiting the COVID-19 pandemic. [ABSTRACT FROM AUTHOR]

Tea is an economically important crop, consumed by billions of people. Despite the increasing market for pesticide-free products, the use of pesticide in tea is still high. In order to investigate whether intercropping promotes biological control organisms, Chamaecrista rotundifolia (Pers.) Greene, Indigofera hendecaphylla Jacq. Trifolium repens L. and Vigna sinensis (L.) were separately intercropped with free weeding as control in a tea plantation at Yangli, China. Arthropods were collected by taking sweep-net samples, and treatment effects on assemblages were investigated. The combined species richness of all arthropods and that of parasitoids was significantly increased in intercropped treatments while the species richness of herbivores and predators was only greater in C. rotundifolia and I. hendecaphylla intercropped treatments. Compared with control, the combined abundance of all arthropods, and that of herbivores was lower, while the abundance of parasitoids and its taxa was greater in all intercropped treatments. The abundance of predators and its taxa was greater only in tea plantations intercropped with C. rotundifolia or I. hendecaphylla. Of the herbivores, the abundance of Empoasca onukii Matsuda, Sternorrhyncha, Aleyrodidae, and Pentatomidae was greater in the areas intercropped with C. rotundifolia in comparison with the control, but the abundance of Thysanoptera and Geometridae caterpillars was lower. The recorded increase in the abundance of beneficial arthropods may explain the lower abundance of Thysanoptera or Geometridae caterpillars detected in the intercropped tea plantations. Our results indicate that intercropping has the potential to enhance arthropod biodiversity, and to provide an option for sustainable pest control in tea plantations. [ABSTRACT FROM AUTHOR]

Aim: Pathologists are currently supposed to be aware of both domestic and international guidelines for breast cancer diagnosis, but it is unclear how successfully these guidelines have been integrated into routine clinical practice in China. Thus, this national proficiency testing (PT) scheme for breast pathology was set up to conduct a baseline assessment of the diagnostic capability of pathologists in China. Methods: This national PT plan is designed and implemented according to the "Conformity assessment—General requirements for proficiency testing" (GB/T27043—2012/ISO/IEC 17043:2010). Five cases of breast cancer with six key items, including histologic type, grade, ER, PR, HER2, and Ki67, were selected for testing among 96 participants. The final PT results were published on the website of the National Quality Control Center for Cancer (http://117.133.40.88:3927/cn/col22/362). Results: Our study demonstrated that the median PT score was 89.5 (54–100). Two institutions with scores < 67 were deemed unacceptable. The accuracy of histologic type, ER, PR, HER2, and Ki67 was satisfactory (all > 86%). However, the histologic grade showed low accuracy (74.0%). The unacceptable results mainly included incorrect evaluation of histologic grade (36.7%), inaccurate evaluation of ER/PR/HER2/Ki67 (28.2%), incorrect identification of C-AD as IBC-NST (15.7%), inappropriate use of 1+/2+/3+ rather than staining percentage for ER/PR (6.1%), misclassification of ER/PR < 1% weak expression as positive staining (1.4%), and no evaluation of histologic grade in ILC, MC, and IMC (5.8%). Conclusions: our nationwide PT program exhibited a satisfactory baseline assessment of the diagnostic capability of pathologists in China. More importantly, we identify some areas for further improvement. [ABSTRACT FROM AUTHOR]

Background: Schistosomiasis transmission is typically focal. Understanding spatial variations of Schistosoma infections and their associated factors is important to help to invent site-specific intervention strategies. Methods: A five-year longitudinal study was carried out prospectively in 12 natural villages, Guichi district of Anhui province. A GIS-based spatial analysis was conducted to identify geographic distribution patterns of schistosomiasis infections at the household scale. Results: The results of the spatial autocorrelation analysis for 2005 showed that there were significant spatial clusters of human infections at the household level, and these results were in agreement with that of the spatial scan statistic. As prevalence of infections in humans decreased over the course of control, the spatial distribution of these infections became less heterogeneous. Conclusions: The findings imply that it may be necessary to re-assess risk factors of S. japonicum transmission over the course of control and to adjust accordingly control measures in the communities. [ABSTRACT FROM AUTHOR]