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Introduction: Intraocular foreign bodies (IOFBs) are a serious subset of open-globe injury that can result in visual loss. This study analyzed the epidemiology, clinical characteristics, and visual outcomes of patients with IOFBs in Southwest China. Methods: This retrospective study comprised 1,176 patients with the primary diagnosis of IOFBs who resided in Sichuan Province over a 10-year period. All data were collected from medical records and analyzed statistically. Results: The annual incidence for IOFBs was 0.14 per 100,000 (95% confidence interval 0.12–0.16 per 100,000) people in Southwest China. In that period, IOFBs accounted for 22.3% of all open-globe injuries. Working-age male patients accounted for 79.1% of all IOFBs patients and there had significant differences in age distributions between genders (p < 0.001). Metallic IOFBs were the most common (74.6%) IOFB, but there were significant differences in the materials of IOFBs between adults and children of different age-groups (p < 0.001). At discharge, 277 (23.6%) patients had increased visual acuity (VA) and 95 (8.0%) had no light perception. Initial VA <20/200 (odds ratio [OR], 5.5; p < 0.001), increasing wound size (OR, 1.3; p = 0.004), IOFBs in the posterior segment (OR, 2.6; p = 0.002) and existing complications (traumatic cataract, endophthalmitis, retinal detachment, or retinal break) were independent risk factors for final VA <20/200. Conclusion: The incidence of IOFBs in Southwest China differed from global statistics. Adults and children had different clinical characteristics. Thus, their prevention strategies should be different. [ABSTRACT FROM AUTHOR]

Based on radiocarbon dating and our analysis of plant and animal remains from Buziping, a Majiayao (5300–4300 BP) and Qijia (4200–3800 BP) period site located in Dingxi, Gansu Province, China, and our review of archaeobotanical studies in the Western Loess Plateau and adjacent areas, we discuss subsistence strategies during the Majiayao and Qijia periods. We also discuss the development of agriculture in the Western Loess Plateau and its influence on cultural expansion during the late Neolithic period. Humans settled at Buziping for the first time during the Majiayao period (4890–4710 cal. yr BP by 14C dating). Charred seeds from the site indicate that people engaged in millet-based agricultural production. People continued this type of agriculture during a second phase of occupation (4130–3880 cal. yr BP by 14C dating) during the Qijia period, but the proportion of foxtail millet to broomcorn millet increased from the Majiayao to Qijia period. Raising domestic animals was another aspect of subsistence during the Qijia period. The main domestic animals were likely pigs and dogs, although hunting of wild animals also took place. Subsistence at Buziping site was affected by the rapid development of intensive agriculture that diffused across eastern Gansu Province during the late Neolithic. Our work suggests that millet-based agriculture spread from east to west across the Western Loess Plateau and likely promoted the expansions of those two cultures in the area during the Majiayao period and early–mid Qijia period. Climate change might have also promoted Majiayao and Qijia expansions and probably facilitated the adoption of rain-fed agriculture in this region. [ABSTRACT FROM AUTHOR]