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In tunnel smooth blasting, optimizing the water interval charging structure of peripheral holes is of great significance in improving the effect of smooth blasting and reducing the unit consumption of explosives. Addressing the issue of a single traditional evaluation standard, this paper proposes a composite index evaluation method for rock blasting damage in different zones, and the best charging structure is optimized according to the evaluation results. Taking Liyue Road Tunnel Light Smooth Blasting Project in Chongqing as the Research Background, the numeric models were established with ten kinds of charge structures, the charge structures and explosive quantity were optimized according to the evaluation results, and then the field tests were conducted. The results show that when the length of the water medium at the bottom of the hole is 20 cm, the damage range of the retained rock mass can be controlled while ensuring rock fragmentation. If the length of the water medium at the orifice and in the center of the hole is more than 30 cm, it will affect the superposition effect of the blast stress wave, resulting in under-excavation; in the preferred charge structure, the ratio of the length of the upper and lower explosives reaches 1:3, and the ratio of the length of the water medium is 2:2:1, which achieves a better rock-breaking effect in the field test. [ABSTRACT FROM AUTHOR]

Respiratory syncytial virus (RSV) is one of the most common causes of lower respiratory tract infections (LRTI). However, only limited information is available regarding its seasonality and its relationship with birth month. A retrospective hospital‐based study was carried out from June 2009 to May 2019 in Chongqing, southwest of China. LRTI cases under 5 years were enrolled in this study and PCR was used to detect 8 respiratory viruses. RSV seasonality was determined using "average annual percentage" (AAP) and "percent positivity" method. A total of 6991 cases were enrolled in this study, with an RSV positivity of 34.5%. From June 2009 to May 2019, we analyzed RSV epidemic season during 10 RSV epidemic years in Chongqing using two methods. The result of AAP method was similar to that of percent positivity method with a 30% threshold, which showed an epidemic season of roughly October to March in the subsequent year, with a small peak in June. On average, the RSV epidemic season in RSV‐A dominant years typically started earlier (week 42 for RSV‐A vs. week 46 for RSV‐B), ended earlier (week 12 for RSV‐A vs. week 14 for RSV‐B), lasted longer (24 weeks for RSV‐A vs. 22 weeks for RSV‐B), and reached its peak earlier (week 2 for RSV‐A vs. week 3 for RSV‐B) than in RSV‐B dominant years. The proportion of severe LRTI was higher in cases of single infection with RSV‐A compared to those of single infection with RSV‐B (26.3% vs. 22.3%, p = 0.024). Among infants under 1 year, those born in May and August through December were more likely to be infected with RSV. Infants born 1–2 months before the epidemic season were relatively more susceptible to RSV infection. In Chongqing, the RSV epidemic was seasonal and usually lasted from October to March of next year with a small peak in summer. Infants born 1–2 months before the epidemic season were relatively more susceptible to RSV infection and this population should be targeted while developing RSV immunization strategies. [ABSTRACT FROM AUTHOR]