1. Nocardia thailandica Pulmonary Nocardiosis in a Post-Solid Organ Transplant Patient.
- Author
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Canterino J, Paniz-Mondolfi A, Brown-Elliott BA, Vientos W, Vasireddy R, Wallace RJ Jr, and Campbell S
- Subjects
- Adenosine Triphosphatases genetics, Aged, Bacterial Proteins genetics, Base Sequence, Connecticut, DNA, Bacterial genetics, DNA, Ribosomal genetics, Heart Transplantation adverse effects, Humans, Immunosuppression Therapy adverse effects, Lung Diseases immunology, Lung Diseases microbiology, Male, Membrane Transport Proteins genetics, Molecular Sequence Data, Nocardia Infections microbiology, RNA, Ribosomal, 16S genetics, SEC Translocation Channels, SecA Proteins, Sequence Analysis, DNA, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Immunocompromised Host immunology, Lung Diseases diagnosis, Nocardia isolation & purification, Nocardia Infections diagnosis, Nocardia Infections immunology
- Abstract
Nocardia thailandica is a rare pathogen related to Nocardia asteroides, Nocardia neocaledoniensis, and Nocardia caishijiensis that, since its original description in 2004, has only been reported to cause wound and ocular infections in humans. We report a case of pulmonary nocardiosis caused by Nocardia thailandica in a 66-year-old solid organ transplant patient from Connecticut, which was identified at the molecular taxonomic level by secA1 analysis, 16S rRNA gene sequencing, and matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS). To our knowledge, this is the first reported case of N. thailandica in the United States and the first report of pulmonary infection by this pathogen in the literature., (Copyright © 2015, American Society for Microbiology. All Rights Reserved.)
- Published
- 2015
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