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In Cuba the intensive use of knowledge has focused on some sectors more than others, despite the high level of training of human resources and the need to boost the Cuban economy with efficiency. This is the reason why the objective of this article is to propose a procedure for the implementation and improvement of knowledge management in Cuban companies. For this purpose, it was created a series of phases that follows a logical sequence for the implementation and improvement of knowledge management in any type of company. [ABSTRACT FROM AUTHOR]

The organizational design constitutes an important source of reservations in the improvement of the competitiveness of the organizations. In correspondence with it, the present work has as objective the organizational redesign of the rums company Agustín Rodríguez Mena, starting from the conception and implementation of a methodological instrument in which are integrated contemporary, sustained managerial philosophies this in the analysis of the state of art of this area of the knowledge, the concrete conditions of the study object, as well as the politicians and strategies of the Cuban State as for the improvement of the systems of managerial address. [ABSTRACT FROM AUTHOR]

The establishment of wellhead protection areas it is a technique of aquifer protection broadly utilized in Cuba, so much for the sources of ground waters for public supply, like for those considered as minerals, however, they are many the causes that impact in the accuracy in its delimitation, therefore, to assume that the calculated areas coincide exactly, with those that in fact should be protected they cause a false sensation of security that can put in risk the health of the population and the own investment. In such a sense, a study has been elaborated in the aquifer Margarita, located in the north of the provincia Villa Clara that shows the limitations of the methods of delimitation of the wellhead protection areas used at the moment in Cuba, using as comparative method to the numeric models VisualModflow to consider occurs bigger precision. Are discussed the causes of the discrepancies in the obtained results and they intend modifications to the methods used in Cuba. The proposed modificacióneses improve in more than 30% the obtained results, what favors their application under the analyzed conditions. [ABSTRACT FROM AUTHOR]

This paper analyzes the behavior and evaluates the competitiveness factors in the province of Villa Clara, supporting the analysis methodology Diamond Porter (1990), the expert method and the study of theoretical and conceptual foundations of competitiveness. The discussion of the results showed the existence of economic, political and social rights that need to be managed in order to contribute to the increased competitiveness in the country through the development of projects, mainly in the productive sectors and in particular in the traditional products and the sugar industry, with the aim of rescuing. Another sector that also contributes to the increase of competitiveness in the territory is the tourism industry, focusing on the territory that the multiplier effect, to enhance the linkage with other sectors, and strengthening the local production. [ABSTRACT FROM AUTHOR]

This work is aimed to measure the organizational atmosphere in a Training Center for the Sugar Industry that is implementing a change process towards a new management system process- oriented to achieve organizational excellence and quality of its management results. Study was made in 122 professionals and employees. It was a transversal study design, analytical and descriptive, made from a confidential questionnaire. The statistical analysis included a basic statistical study and a factor analysis of principal components. There are three factors that define the organizational atmosphere with a representativity of 82, 3%. As a main conclusion of research work it was considered the immediate introduction of modifications in style and management methods as well as in workers' attitude, in correspondence with the organizational strategy and its management system. [ABSTRACT FROM AUTHOR]

Atherosclerosis, is the most common process subordinated to cardiovascular morbidity and mortality. The isquemic cardiopatic as consequence of the atherosclerotic process, has in Cuba the first place among non violent dysfunctions. The participation of the immune system in the atherosclerosis has studied in the last years. In this paper we proposed to obtain an passive experimental model of atherosclerosis induced by immune complex in BALB/CBJ Hepatitis B surface antigen (HbsAg) transgenic (Tg) mice. We obtain antibodies against the HBsAg (anti-HBs) developing ascitis rich in these antibodies in BALB/CBJ isogenic mice. We employed two groups of BALB/CBJ female mice transgenic to HBsAg of six weeks of age under a regimen of water and food at libitum. We quantified the concentration of HBsAg in the animals by means of an immunoenzimatic method. Later we performance seven inoculations by the caudal vein with an interval of five days between them, utilizing the anti-HBs that was obtained previously in the study group with a dose that duplicated the HBsAg concentration of each animal, in the control group we used ascites free of these antibodies with the same procedure. A week after these immunizations we took blood samples of the animals to determine the circulates immune complex in plasma. The animals were sacrificed by cervical dislocation and the presence of atherosclerotic lesions in the aorta was observed by macroscopic and microscopic manner. In the study group we observed the presence of atheroma plaques but not in the controls in both groups we observed the fatty streaks. The circulates immune complex were detected in both groups. With these results we concluded that we obtained an atherosclerosis model in BALB/CBJ isogenic mice by passive way of immune complex formation. [ABSTRACT FROM AUTHOR]

Atherosclerosis, is the most common process subordinated to cardiovascular morbidity and mortality. The isquemic cardiopatic as consequence of the atherosclerotic process has in Cuba the first place among non violent dysfunctions. The participation of the immune system in the atherosclerosis has studied in the last years. In this paper we proposed to obtain an active experimental model of atherosclerosis induced by immune complex in BALB/CBJ isogenic mice. We employed male mice of six weeks of age under a regimen of water and food at libitum. These animals were divided in two groups, one of them received a scheme of 0-1-4 weeks intraperitoneal via with the cuban anti Hepatitis B vaccine Heberbiovac HB. The other group was the control and was immunized the same way employing the excipient of the vaccine without the Hepatitis B surface antigen (HBsAg). When the scheme finalized we took blood samples of the animals and we quantified the antibodies against the HBsAg (anti-HBs) by means of an immunoenzimatic method. Later we performance seven immunizations by the caudal vein with an interval of five days between them, utilizing as immunogen recombinant HBsAg in the study group with a dose that duplicated the anti-HBs concentration of each animal, in the control group we used saline solution with the same procedure. A week after these immunizations we took blood samples of the animals to determine the circulates immune complex in plasma. During the experiment the animals of the study group inhaled cigarette smoke. The animals were sacrificed by cervical dislocation and the presence of atherosclerotic lesions in the aorta was observed by macroscopic and microscopic manner. In the study group we observed the presence of atheroma plaques but not in the controls in both groups we observed the fatty streaks. The circulates immune complex were detected in none groups. With these results we concluded that we obtained an atherosclerosis model in BALB/CBJ isogenic mice by active way of immune complex formation. [ABSTRACT FROM AUTHOR]