1. Differences in the etiology of chronic non-alcoholic liver disease in Naples and Copenhagen.
- Author
-
Del Vecchio-Blanco C, Caporaso N, Tage-Jensen U, Di Sapio M, and Schlichting P
- Subjects
- Adult, Aged, Antibodies, Antinuclear analysis, Autoantibodies analysis, Denmark, Female, Fluorescent Antibody Technique, Hepatitis B Surface Antigens analysis, Hepatitis, Chronic epidemiology, Hepatitis, Chronic immunology, Humans, Italy, Liver Cirrhosis epidemiology, Liver Cirrhosis immunology, Male, Middle Aged, Hepatitis, Chronic etiology, Liver Cirrhosis etiology
- Abstract
A group of patients with non-alcoholic chronic liver disease from Copenhagen (148) and one from Naples (116) were investigated for the presence of viral and autoimmune serological variables by standardized methods. There were more hepatitis B virus (HBV)-induced cases among the Italians (38.8 versus 15.5%), but the sex ratio and biochemical activity were not different from the Danish ones. Autoimmune markers were much more frequent and in higher titers in Danish HBV-negative patients than in Italian ones. Fewer were women, and thus few Italians fit the theory of autoimmune pathology; rather, their chronic liver disease is caused by other hepatitis viruses than B.
- Published
- 1984