1. 'Partial D' women with anti-D alloimmunization in pregnancy.
- Author
-
Mayne KM, Allen DL, and Bowell PJ
- Subjects
- England epidemiology, Epitopes immunology, Female, Fetal Blood immunology, Humans, Incidence, Infant, Newborn, Pregnancy Outcome, Retrospective Studies, Isoantibodies blood, Pregnancy immunology, Rh Isoimmunization epidemiology, Rh-Hr Blood-Group System immunology
- Abstract
We report five women with Rh 'partial D' who were found to have anti-D during pregnancy. Two patients were category IVa, their red cells typing as Go(a+); one was category VI; and two had a 'partial Du' which could not be categorized. The maternal anti-D concentration increased during four of the eight pregnancies studied, but none reached significant levels. Three of six D-positive cord blood samples had a positive direct antiglobulin test (DAGT). Although one baby became jaundiced, no treatment was required. The policy in the Oxford Region for the management of patients with a weak expression of D is outlined.
- Published
- 1991
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