Search

This article investigates to what extent disrupted schooling due to the COVID-19 pandemic has affected pre-primary-age children's school readiness in Ethiopia. We use data on early numeracy of 2,640 children collected before and after the eight-month school closure to assess their learning progress in the context of COVID-19. We find that children who attended pre-primary school prior to the school closures performed better than those who did not after schools re-opened, and made greater gains in early numeracy at primary school entry. For children who attended pre-primary education, boys, children with literate caregivers, and those from wealthier families show significantly greater learning gains than their peers, which raised concerns about widening learning inequality as a result of the pandemic. Given that pre-primary education was the most neglected part of the government's COVID-19 education response, these findings point to an urgent need for political leadership to prioritize pre-primary education in responding to the current and future crises.

This study uncovers controversies about the use of mother tongue as a medium of instruction in Ethiopia. It examines motives for the use of the mother tongue as a medium of instruction at the elementary level, and on which grounds the rights of minority linguistic groups to be instructed in their mother tongue are overlooked. To this effect, data were gathered from government language policy-related documents as well as 28 purposefully selected key informants through in-depth interviews. The data were analysed through a critical discourse analysis approach. Data showed that the government uses mother-tongue education for political motives and has the power to put its political interests into practice without conducting any societal needs assessments. On the other hand, the government lacks commitment to putting its language-use ideology into practice. It has used only some of the languages as mediums of instruction, with the result that many children of minority groups are not learning their daily lessons effectively. The study recommends that the government should confirm the right to learn through mother-tongue instruction at an elementary level to benefit children so that they can enjoy the opportunities of learning in their languages.

Recent research on the effects of COVID-19 on school closures has mainly focused on primary and secondary education, with extremely limited attention to early childhood education (ECE). To address this gap, we identify the extent to which parents and caregivers with pre-primary school-aged children were engaged in their children's learning during school closures in Ethiopia. Our focus on Ethiopia is of particular relevance given that ECE provision has expanded dramatically in recent years, aimed at ensuring children are prepared for primary school. Using data collected through a phone survey with 480 parents and caregivers, the results revealed that learning disruption due to COVID-19 school closures is likely to be substantial and will probably widen existing inequalities further. Many poorer households and those where parents or caregivers are not literate, are less likely to have child-oriented learning resources, and home learning activities between parents and children in these households are limited. The study highlights that greater attention needs to be paid to mitigate the threats of COVID-19 on Ethiopia's recent gains in ECE, to prevent the pandemic from further reinforcing inequalities between children from advantaged and disadvantaged households.

The purpose of the study was to assess the perception and challenges of prospective teachers towards school-based teaching practice in the case of Mekelle University, Ethiopia. For this study, a descriptive survey method has been used. The source of data for this study was the Post Graduate Diploma in Teaching (PGDT) students in the academic year of 2018/2019. The total number of populations in the study was 142, and out of these 80 of them were selected as a sample by using a random sampling technique. The perception and challenges towards school-based teaching practice, was validated by investigators using five point Likert type scale. The scale was used to generate the required data. The data collected from the study participants were analyzed quantitatively. The findings of the study reveal that: (1) prospective teachers have positive perception towards the role of school-based teaching practice in promoting their pedagogical skills as well as subject knowledge; (2) prospective teachers were less satisfied with the collaborative work and feedbacks, they had got from their respective mentors during the school-based teaching practice; and (3) even though school-based teaching practice in the case of Mekelle University has considerable challenges, the most serious problems were practicing period was short, lack of transportation fare on the part of student-teachers, lack of adequate school facilities, and lack of cooperativeness among the University. Based on the findings of this study some recommendations are given on how to improve students' perception and challenges such as: (1) the Ministry of education should provide enough finance for transportation of student-teachers and to realize school facilities in the school; and (2) the University should arrange a proper orientation for student-teachers mentors and tutors to use efficiently means of conferences and discussion before they go for teaching practice.

There is a severe shortage of services for children with autism in Ethiopia; access to services is further impeded by negative beliefs and stigmatising attitudes towards affected children and their families. To increase access to services, care provision is decentralised through task-shifted care by community health extension workers. This study aimed to examine the impact of a brief training (Health Education and Training; HEAT) for Ethiopian rural health extension workers and comprised three groups: (1) health extension workers who completed a basic mental health training module (HEAT group, N = 104); (2) health extension workers who received enhanced training, comprising basic HEAT as well as video-based training on developmental disorders and a mental health pocket guide (HEAT+ group, N = 97); and (3) health extension workers untrained in mental health (N = 108). All participants completed a questionnaire assessing beliefs and social distance towards children with autism. Both the HEAT and HEAT+ group showed fewer negative beliefs and decreased social distance towards children with autism compared to the untrained health extension worker group, with the HEAT+ group outperforming the HEAT group. However, HEAT+ trained health extension workers were less likely to have positive expectations about children with autism than untrained health extension workers. These findings have relevance for task-sharing and scale up of autism services in low-resource settings worldwide.

The establishment of secured and easily transferable land use rights is a key component of rural development and poverty reduction pathways in many underdeveloped countries. In this study, we use balanced panel data collected from 407 farm households between 2009/10 and 2014/15 production seasons and apply difference‐in‐difference approach to examine impact of second‐stage land certification on tenure security, participation and extent of participation in the land rental market. Our finding shows that second‐stage land certification has helped to boost tenure security of smallholder farmers. However, the differences in difference results show that the second stage land certification has not yet started to influence farm households' participation in the land rental market. This could probably be due to the fact that the program is at its early stage of implementation and may warrant further scrutiny with additional time. [ABSTRACT FROM AUTHOR]

Background: Hepatitis B (HBV) and C virus (HCV) coinfection are the major causes of liver-related morbidity and mortality among people living with Human Immunodeficiency Virus (HIV). The burden of hepatitis among HIV-positive individuals has not been studied in the Afar region. Therefore, this study aimed to determine the prevalence of HBV and HCV coinfection and associated factors among HIV-positive patients in Afar Regional State, northeast Ethiopia. Methods: A cross-sectional study was conducted on 477 HIV-positive patients between February 2019 and May 2019. A structured and pretested questionnaire was used to collect socio-demographic data and associated factors. Five milliliters of blood was collected, and Hepatitis B surface antigen (HBsAg) and HCV antibodies were detected using rapid test kits. Positive samples were confirmed using enzyme-linked immunosorbent assay (ELISA). Binary and multivariable logistic regression analyses were performed to identify associated factors. Statistical significance was set at P <0.05. Results: Among the 477 study participants, 320/477(67.1%) of them were females and 157(32.9%) males. The overall prevalence of HIV-HBV and HIV-HCV coinfection was 25(5.2%) and 7(1.5%), respectively. Multi-sexual practice was significantly associated with HIV-HBV coinfection (AOR = 5.3; 95% CI: 1.2–24.4, P = 0.032). Conclusion: The prevalence of both HIV-HBV and HIV-HCV coinfection was intermediate. Multi-sexual practice was significantly associated with HIV-HBV coinfection. Screening of all HIV-positive patients for HBV and HCV and health education regarding the transmission modes should be considered. [ABSTRACT FROM AUTHOR]

Background: Infertility is a marginalized sexual and reproductive health issue in low-resource settings. Globally, millions are affected by infertility, but the lack of a universal definition makes it difficult to estimate the prevalence of infertility at the population level. Estimating the prevalence of infertility may inform targeted and accessible intervention, especially for a resource-limited country like Ethiopia. This study aims to estimate the prevalence of female infertility in Ethiopia using the Demographic and Health Survey (DHS) through two approaches: (i) the demographic approach and (ii) the current duration approach. Methods: Data from 15,683 women were obtained through the 2016 Ethiopian DHS. The demographic approach estimates infertility among women who had been married/in a union for at least five years, had never used contraceptives, and had a fertility desire. The current duration approach includes women at risk of pregnancy at the time of the survey and determines their current length of time-at-risk of pregnancy at 12, 24, and 36 months. Logistic regression analysis estimated the prevalence of infertility and factors associated using the demographic approach. Parametric survival analysis estimated the prevalence of infertility using the current duration approach. All estimates used sampling weights to account for the DHS sampling design. STATA 14 and R were used to perform the statistical analysis. Results: Using the demographic definition, the prevalence of infertility was 7.6% (95% CI 6.6–8.8). When stratified as primary and secondary infertility, the prevalence was 1.4% (95% CI 1.0-1.9) and 8.7% (95% CI 7.5–10.1), respectively. Using the current duration approach definition, the prevalence of overall infertility was 24.1% (95% CI 18.8–34.0) at 12-months, 13.4% (95% CI 10.1–18.6) at 24-months, and 8.8% (95% CI 6.5–12.3) at 36-months. Conclusion: The demographic definition of infertility resulted in a lower estimate of infertility. The current duration approach definition could be more appropriate for the early detection and management of infertility in Ethiopia. The findings also highlight the need for a comprehensive definition of and emphasis on infertility. Future population-based surveys should incorporate direct questions related to infertility to facilitate epidemiological surveillance. [ABSTRACT FROM AUTHOR]

Background: Considering individual differences caused by personality differences is crucial for end users' technology acceptance. However, previous studies overlooked the influence of users' technology readiness on technology acceptance. This study, therefore, aimed to evaluate the influence of technology readiness on teleradiology acceptance in the Amhara Regional State Public Hospitals using a technology readiness acceptance model. Methods: An institutional-based cross-sectional mixed study design was conducted in September 2021 among 547 health professionals working at sixteen public hospitals in the Amhara region of northwest Ethiopia. Eight key informants were interviewed to explore organizational-related factors. Face-to-face and Google Meet approaches were used to collect the data. We applied structural equation modeling to investigate the influence of technology readiness on health professionals' teleradiology acceptance using Analysis of Moment Structures Version 23 software. Results: Of the total participants, 70.2% and 85.7% were ready and intended to use teleradiology, respectively. According to technology readiness measuring constructs, optimism and innovativeness positively influenced health professionals' technology acceptance. Perceived ease of use and perceived usefulness showed a statistically positive significant effect on health professionals' intention to use teleradiology. In addition, a statistically significant mediation effect was observed between technology readiness measuring constructs and behavioral intention to use. Furthermore, a shortage of budget, inadequate infrastructure, and users' lack of adequate skills were reported as critical organizational challenges. Conclusions: We found a higher proportion of readiness and intention to use teleradiology among health professionals. Personality difference measuring constructs and organizational factors played considerable influence on teleradiology acceptance. Therefore, before the actual implementation of teleradiology, ensuring the system's user-friendliness, improving infrastructure, allocating an adequate budget, and availing of capacity-building opportunities are recommended. [ABSTRACT FROM AUTHOR]

Background: Campylobacter species are the most predominant bacterial agents to cause diarrhea in under-five children. It poses a serious challenge to public health worldwide with ongoing acquisition of resistance to different antimicrobials with multiple patterns. Thus, this study aimed to determine the prevalence, and antimicrobial resistance of Campylobacter species, and associated factors among under-five children with diarrhea in selected public health facilities. Methods: A cross-sectional study was conducted among under-five children with diarrhea using convenient sampling. Health facilities were selected using a simple random sampling method. The stool samples collected from 214 study participants were transported and processed following standard microbiological protocols. Campylobacter isolates were identified using Gram staining, biochemical test, serological test, and aerobic growth at 25°C. Antimicrobial susceptibility profiles of isolates were performed using the Kirby–Bauer method. Data were analyzed using SPSS ver. 25.0. Association between variables was assessed using Chi-square test and Logistic regression, with P ≤ 0.05. Results: The subject's mean age was 31.3 (± 3.9) months. Of the 214 samples cultured, 14 (6.5%) of them were positive for Campylobacter species with 95% CI (3.3– 10.3). Out of the isolated species, 12 (85.7%) were Campylobacter jejuni /Campylobacter coli and 2 (14.3%) were other Campylobacter species. Bottle feeding and history of direct contact to domestic animals were associated with Campylobacter species (AOR=5.13, CI=1.21– 21.6, p=0.026 and AOR=4.93, CI=1.33– 18.17, P=0.016), respectively. Campylobacter isolates were highly resistant to ciprofloxacin 5 (35.7%), and tetracycline 3 (21.4%). Conclusion: A higher incidence of Campylobacter species was obtained in children who were bottle-fed and who had a history of direct contact with domestic animals. The isolates were highly resistant to ciprofloxacin and tetracycline. These findings indicate that special attention is needed for better management of Campylobacter drug resistance in under-five children. To enhance and support our current findings, further research using molecular techniques is needed to identify the resistant and virulent genes of the bacterial isolates. [ABSTRACT FROM AUTHOR]

Introduction: Arboviral diseases, such as dengue, chikungunya, yellow fever, and Zika, are caused by viruses that are transmitted to humans through mosquito bites. However, the status of arbovirus vectors in eastern Ethiopia is unknown. The aim of this study was to investigate distribution, breeding habitat, bionomics and phylogenetic relationship of Aedes aegypti mosquito species in Somali Regional State, Eastern Ethiopia. Methods: Entomological surveys were conducted in four sites including Jigjiga, Degehabur, Kebridehar and Godey in 2018 (October to December) to study the distribution of Ae. aegypti and with a follow-up collection in 2020 (July-December). In addition, an investigation into the seasonality and bionomics of Ae. aegypti was conducted in 2021 (January-April) in Kebridehar town. Adult mosquitoes were collected from indoor and outdoor locations using CDC light traps (LTs), pyrethrum spray collection (PSCs), and aspirators. Larvae and pupae were also collected from a total of 169 water-holding containers using a dipper between October and November 2020 (rainy season) in Kebridehar town. The species identification of wild caught and reared adults was conducted using a taxonomic key. In addition, species identification using mitochondrial and nuclear genes maximum likelihood-based phylogenetic analysis was performed. Results: In the 2018 collection, Ae. aegypti was found in all study sites (Jigjiga, Degahabour, Kebridehar and Godey). In the 2020–2021 collection, a total of 470 (Female = 341, Male = 129) wild caught adult Ae. aegypti mosquitoes were collected, mostly during the rainy season with the highest frequency in November (n = 177) while the lowest abundance was in the dry season (n = 14) for both February and March. The majority of Ae. aegypt were caught using PSC (n = 365) followed by CDC LT (n = 102) and least were collected by aspirator from an animal shelter (n = 3). Aedes aegypti larval density was highest in tires (0.97 larvae per dip) followed by cemented cisterns (0.73 larvae per dip) and the Relative Breeding Index (RBI) was 0.87 and Container Index (CI) was 0.56. Genetic analysis of ITS2 and COI revealed one and 18 haplotypes, respectively and phylogenetic analysis confirmed species identification. The 2022 collection revealed no Ae. aegpti, but two previously uncharacterized species to that region. Phylogenetic analysis of these two species revealed their identities as Ae. hirsutus and Culiseta longiareolata. Conclusion: Data from our study indicate that, Ae. aegypti is present both during the wet and dry seasons due to the availability of breeding habitats, including water containers like cemented cisterns, tires, barrels, and plastic containers. This study emphasizes the necessity of establishing a national entomological surveillance program for Aedes in Somali region. [ABSTRACT FROM AUTHOR]

This article investigates to what extent disrupted schooling due to the COVID-19 pandemic has affected pre-primary-age children's school readiness in Ethiopia. We use data on early numeracy of 2,640 children collected before and after the eight-month school closure to assess their learning progress in the context of COVID-19. We find that children who attended pre-primary school prior to the school closures performed better than those who did not after schools re-opened, and made greater gains in early numeracy at primary school entry. For children who attended pre-primary education, boys, children with literate caregivers, and those from wealthier families show significantly greater learning gains than their peers, which raised concerns about widening learning inequality as a result of the pandemic. Given that pre-primary education was the most neglected part of the government's COVID-19 education response, these findings point to an urgent need for political leadership to prioritize pre-primary education in responding to the current and future crises. [ABSTRACT FROM AUTHOR]

We report 4 cases of human African trypanosomiasis that occurred in Ethiopia in 2022, thirty years after the last previously reported case in the country. Two of 4 patients died before medicine became available. We identified the infecting parasite as Trypanosoma brucei rhodesiense. Those cases imply human African trypanosomiasis has reemerged. [ABSTRACT FROM AUTHOR]

Background: Bacterial otitis media (OM) is a common infection among the pediatric community worldwide and is the first reason for prescribing antibiotics in pediatric practices. However, if not promptly diagnosed and appropriately treated, it may persist and cause severe intra- and extra-cranial hard-to-cure complications. Hence, knowing the magnitude, etiology, and antibiotic susceptibility profile is very important for the proper management.Methods: A cross-sectional study was carried out in 312 pediatrics (1 to 18 years) attending the Ear Nose Throat outpatient departments of the two title hospitals from 25 February to 30th August 2022. Patients were chosen through a systematic random sampling method. Data were obtained by means of a semi-structured questionnaire. Samples were collected to identify the causative bacteria as per microbiological guidelines. The antibiotic susceptibility test was done according to the Kirby–Bauer disc diffusion; SPSS version 25 was used for the analysis.Results: The overall prevalence of otitis media was 67.3% (n=210); CSOM showed a slight preponderance (n=107) Gram-negative bacteria and Gram-positive bacteria were present in 59.8% (n=137) and 40.1% (n=92), respectively. Otitis media was predominantly caused by S. aureus (n=52, 56.5%), followed by Proteus spp. (n=33, 24%). Gram-negative bacteria were highly resistant to co-trimoxazole, amoxicillin-clavulanic acid, piperacillin, and tetracycline, whereas their positive counterparts were considerably penicillin and co-trimoxazole resistant. Overall, 61.5 and 19.2% of the isolates were MDR and XDR, respectively. MRSA, MR-CoNs, and VRE were 38.4% (n=20), 17.1% (n=5), and 58.3% (n=12), respectively; 19.7% (n=25) of Gram-negative bacteria produced ESBL, and 7% (n=9) were carbapenem-resistant. History of exposure to loud noise [AOR=3.4; CI=1.14– 10.23; P-value=0.028] and family history of smoking at home [AOR=2.9; CI=1.18– 7.25; P-value=0.020] have the greatest odds of otitis media.Conclusion: Overall, the prevalence of otitis media is showing an upward trend, and MDR among bacterial isolates is increasing alarmingly. [ABSTRACT FROM AUTHOR]

Introduction: surgical patients often suffer from inadequate treatment of post-operative pain which potentially results in numerous adverse medical consequences and is a recurring source of patients' dissatisfaction. Thus, this study aimed to investigate patient's satisfaction with their postoperative pain management and its determinants among surgically treated patients in a specialized hospital within Ethiopia. Methods: an institutionalbased prospective cross-sectional study was conducted in the surgical ward of Ayder Comprehensive Specialized Hospital. Data were collected using a semi-structured questionnaire, which was an adoption of the 2010 version of the American Pain Society Patient Outcome Questionnaire, and by reviewing the medical charts of the patients. A stepwise linear regression model was used to analyze the data. Results: among the 144 patients approached in this study, 112 (77.8%) of them categorized their postoperative pain as moderate to severe. The mean patient satisfaction with their pain management was 7±2.3 on 0-10 numerical rating scale. Despite high levels of pain, the majority of patients (90.3%, n=131) were moderately or completely satisfied with their pain management. Stepwise linear regression analysis found that the determinants of patients' satisfaction were prior chronic pain, prior surgical history, and substance use (F (3,140) = 5.364, adjusted R2= 0.084, P=0.02). Conclusion: the patients were moderately and completely satisfied with their pain management in spite of expressing moderate and severe level of pain intensity. Pain still remains a concern among surgical patients, and effective pain management strategies should be practiced to manage pain and its functional interferences more effectively. [ABSTRACT FROM AUTHOR]

The growing needs for agricultural production require maintaining and improving soil fertility through fertilization. However, most research to date in Ethiopia particularly in the Tigray regional state has focused on the effects of soil chemical properties and relatively little work has been done on soil physical properties. The objective of this study was to assess the effects of compost, blended (NPSZn), and potassium chloride (KCl) fertilizers on soil bulk density (BD) and moisture content (SMC). Therefore, a field experiment was carried out for 2018-2019 years to study the influence of sole and combined application of compost, NPSZn, and KCl fertilizers on BD and SMC in clay loam and loamy sand soil textures in Tigray. Two compost (0 and 20 t·ha−1), three NPSZn (0, 60, and 120 kg·ha−1), and four KCl (0, 120, 210, and 300 kg·ha−1) rates replicated three times were arranged in split-split plot design and allocated to main, sub, and sub-subplots, respectively. BD (g·cm−3) and SMC (%) data were collected from 0 to 10 and 0 to 30 cm soil depths before and after harvesting in 2018 and 2019, respectively. Sole and combined application of the fertilizers considerably influenced BD and SMC in both soil textural groups and years. Compost applied in combination with NPSZn at 120 kg·ha−1 and KCl at 300 kg·ha−1 significantly reduced BD (1.24 g·cm−3 in 2018 and 1.22 g·cm−3 in 2019) in clay loam soils as compared to all treatments. Similarly, the lowest BD (1.5 g·cm−3 in 2018 and 1.47 g·cm−3 in 2019) was observed in loamy sand soils. The highest volumetric SMC (21% in both years) was observed in clay loam soil in plots treated with compost. Likewise, the highest SMC (12% in 2018 and 11% in 2019) was found in loamy sand soils in compost-treated plots. This study demonstrated that SMC and BD can be improved through compost and compost combined with NPSZn and KCl application, respectively, in the drylands of Northern Ethiopia. [ABSTRACT FROM AUTHOR]

The varroa mite (Varroa destructor) is the most economically important parasitic pest of honey bees (Apis mellifera) that causes global colony decline and loss. Since its first detection in Ethiopia in 2010, little is known about the current infestation levels and contributing factors to the mite's distribution across the country. In this study, we conducted a large‐scale assessment of varroa prevalence and infestation levels in managed colonies across three potential beekeeping regions of Ethiopia; Oromia, Amhara and Southern Nations, Nationalities and Peoples Region (SNNPR). A total of 360 samples from 39 apiaries were collected following standard protocols and the mite prevalence and infestation levels were determined using the established method of varroa research. Overall, 89% of sampled colonies were infested by the mite, with varying prevalence rates across the regions: 95.8% in Oromia, 85.2% in Amhara and 71.9% in SNNPR, indicating the widespread nature of the parasite throughout the country. The varroa infestation levels were lower in local hives (2.6 ± 5.9) than in frame hives (5.0 ± 0.9), and significantly higher in brood bees (5.6 ± 0.8) than in adult bees (1.93 ± 0.17) (p < 0.001). Possible factors contributing to the varied mite prevalence and infestation levels in the country include differences in agro‐ecology, beekeeping practices, host age preference and the nature of bee hives. Therefore, our study provides insights into the current status of varroa prevalence and associated factors across regions in Ethiopia. Further investigation is required to explore the probable impact of the parasite on the health and productivity of local honey bees, in order to design future monitoring strategies. [ABSTRACT FROM AUTHOR]

Field survey, focus group discussions and key informants' interview were conducted to collect data on the effects of degraded hillsides allocation to landless youth groups. Data on vegetation recovery, and status of physical soil and water conservation structures were collected from 3 allocated and 3 adjacently non-allocated hillsides. Our findings indicated that hillside allocation improved the length of physical soil and water conservation structures by 58% (from 1310 meters ha-1 on communal hillsides to 2067 meters ha-1 on allocated hillsides). Hillside allocation to landless youth also improved tree survival rate, number of woody species and species diversity by 25%, 14% and up-to 62%, respectively. It can be concluded that allocation of communal hillsides to landless youth resulted in improved land management and vegetation cover on top of their economic benefits. This implies that the strategy can be taken as a potential option to overcome the challenges of land degradation. [ABSTRACT FROM AUTHOR]

Background: Tuberculosis (TB) continues to be a global health problem. While childhood TB contributes 10% to the global TB burden, the paucibacillary nature of TB disease in children and the absence of reliable diagnostic methods have made MTB diagnosis in children to be a great challenge. This study aimed to determine the prevalence of MTB and rifampicin-resistant MTB (RR-MTB) among children using Gene Xpert MTB/RIF Assay in Tigray, Ethiopia.Methods: A retrospective database study was conducted among children in ten governmental hospitals in the Tigray region. Gene Xpert MTB/RIF results of sputum/gastric lavage samples from children with presumptive TB from January 2016 to December 2019 were extracted using a data extraction sheet. Data were collected and analyzed using Statistical Package for the Social Sciences version 21.Results: The prevalence of bacteriologically confirmed MTB by Gene-Xpert in children with presumptive TB was 7.3% (95% CI: 6.7%− 7.9%) and the proportion of those that were Gene-Xpert MTB positive who also have rifampicin resistance was 10.9% (95% CI: 8.2– 13.6%). Older children aged 11– 15 years [AOR = 1.76; 95% CI = 1.33– 2.33, p < 0.001] and adolescents 16– 17 years [AOR = 2.18; 95% CI = 1.63– 2.92, p < 0.001] were more likely to be MTB positive. Relapse cases [AOR = 1.66; 95% CI = 1.09– 2.51, p = 0.017] and lost/failure cases [AOR = 8.82; 95% CI = 3.94– 19.76, p < 0.001] were more likely to have MTB compared to the new cases.Conclusion: The proportion of MTB-positive among the TB presumptive patients was 7.3%. The proportion of rifampicin-resistant TB to all positive patients was 10.9%. Female participants had more MTB than males (or younger children). The result highlights the need for due attention in children because it is very helpful in determining the future control of the disease. [ABSTRACT FROM AUTHOR]

The long stratigraphic sequence of the Shungura Formation in the Lower Omo Valley documents 3 million years (Ma) of hominin evolution, which, when combined with detailed paleo-depositional environmental data, opens new perspectives for understanding the complex interactions between hominin landscape use and the development of stone tool-mediated activities. Stone tool assemblages produced by Paranthropus aethiopicus and/or a species of early Homo from ~ 2.3 Ma, reflect their ability to deal with the raw material scarce environment of the Lower Omo Valley. It remains to be seen whether this activity can be related to a single, brief occupation event or the expression of an emergent new adaptation. Here we report on the newly investigated site complex of OMO 79, which produced the first evidence for multiple phases of hominin tool-making and use in the Shungura Formation. The development of this long-lasting techno-economic behavior marks a cognitive tipping point around 2.3 Ma in the Lower Omo Valley, evidenced by the adaptability of the early hominins to resource-constrained environments. [ABSTRACT FROM AUTHOR]

Soil characterization is crucial in creating sustainable platforms for land users to identify areas vulnerable to anthropogenic activities. This study was conducted to investigate the impacts of lithology, slope, and land use on soil properties of a semi-arid highland in northern Ethiopia. Disturbed and undisturbed soil samples collected from 0 to 30 cm depth were analyzed. Most of the assessed physical and biochemical soil properties varied significantly (p < 0.05) with lithology, slope class, and land use type. Shale-originated soils were richer in nutrients than soils of other lithologies. A decrease in slope gradient accounted for an increase in most soil properties, while a reverse trend was observed for sand content, bulk density (BD), water stable aggregates (WSA), mean weight diameter (MWD), structural stability index (SSI), soil organic carbon (SOC), total nitrogen (TN), and available phosphorus (AP). Silt and clay fractions, total porosity, moisture content at field capacity and wilting point, visual evaluation of soil structure, pH, electrical conductivity, calcium carbonate, exchangeable bases, cation exchange capacity, and percent base saturation were found to be higher for cultivated land soils compared to grass land and shrub land soils. Shrub land soils, in contrast, had higher WSA, MWD, SSI, SOC, TN, and AP relative to grass land and cultivated land soils. In summary, slope class and land use type stood out as the major drivers influencing the dynamics and distribution of soil properties other than lithology and their interactions in semi-arid highlands of northern Ethiopia. Thus, from sustainability point of view and in the light of their nutrient retention capability and limitation, more attention should be paid toward ensuring periodic assessment and sustainable management of soils in steep cultivated lands. [ABSTRACT FROM AUTHOR]

Land rehabilitation through exclosures has been recognized as a promising practice in the restoration of degraded drylands. This study evaluated woody species density, diversity, cover, and biomass production from three regeneration approaches (EMTs): (1) Naturally Regenerated (ENR) exclosures, (2) exclosures with Soil and Water Conservation Structures (ECNR), and (3) those enriched with exotic and local plant species in addition to SWC structures (ECP) among which empirical evidence of comparisons are lacking for appropriate decision making of which restoration strategy to promote. Primary data were collected from a total of 72 study plots located across transects laid within exclosures and in adjacent grazing areas with similar ecological condition. Interview with 331 households and focus groups was used to further understand the effects. Regression analysis revealed that the mean difference in herbaceous and canopy cover, herbaceous and woody biomass, and woody species density and diversity of the three EMTs was statistically significantly higher than in the adjacent open grazing areas. Moreover, herbaceous biomass in ECP differed significantly from that of ECNR. The results indicated that ENR and ECP equally enhanced the selected vegetation parameters. This is predominantly attributed to the comparable responsiveness of many degraded areas to natural regeneration as they do to active regeneration approaches. Implementation of natural regeneration is suitable for immediate recruitment of strategy in terms of resources, time, and meeting objectives before decisions are made for assisted models of exclosure that require massive campaigns to construct soil and water conservation structures and huge seedling production in the dryland areas. [ABSTRACT FROM AUTHOR]

Background: Tele-education is the use of ICTs to conduct remote learning. It has been utilized to deliver ongoing training for many years. The world's modern culture is increasingly reliant on the use of information technology to enhance standards of education. However, in order to deploy successful e-learning systems in a developing nation, understanding of user characteristics is required in the creation and usage of e-learning systems. Thus, this study will enable us to understand the user's level of knowledge and attitude towards tele-education. Methods: An institution-based quantitative cross-sectional study supported by qualitative design was used 397 medical students at University of Gondar from May to June 2022. A pre-tested self-administered structured questionnaires and in-depth interview were used to collect quantitative and qualitative data respectively. Thematic-content analysis was conducted using open-code software for analyzing qualitative data. Quantitative data was entered to Epi-data version 4.6 and exported to SPSS version 25 software for further statistical analysis. Binary logistic regression was conducted. The adjusted odds ratio(AOR) was used to measure the association between the dependent and independent variables. Results: A total of 397 medical students were participated in this study with a response rate of 93.63%. In this study nearly six out of ten 230(57.9%) of study participants had good knowledge towards tele-education. More than half. 211(53.1%) of medical students participated on the study also had a favorable attitude towards tele-education. Factors associated with knowledge about tele-education is training related to ICT (AOR = 2.27 95% CI; (1.13,4.55)), knowledge of medical education digitization (AOR = 3.80 95% CI; (2.12,6.84)), high computer literacy (AOR = 2.82 95% CI; (1.68,4.72)) and favorable attitude towards tele-education (AOR = 3.52 95% CI; (2.12,5.84)). Factors associated with attitude towards tele-education is age group > 21 (AOR = 3.89, 95% CI; (1.33,11.39)) and good knowledge towards tele-education (AOR = 3.42,95%CI;(2.06,5.66)). Conclusion: The study revealed that the knowledge of the medical students was good and nearly five out of ten of them had a favorable attitude towards tele-education. The study shows that training related to ICT, knowledge of medical education digitization, high computer literacy and favorable attitude towards tele-education were associated significantly with knowledge of tele-education. In this study age group > 21 and good knowledge towards tele-education of study participants were associated significantly with attitude towards tele-education. [ABSTRACT FROM AUTHOR]

Background: More than 1.7 billion people are affected by neglected tropical diseases (NTDs) worldwide. Forty percent of the NTD-affected people live in Africa with the poorest, most vulnerable, and hard to reach geographical areas. The NTDs cause significant social and economic burden and deepen marginalization and stigmatization. The World Health Organization's current roadmap for NTD aims to prevent, control, eliminate, or eradicate 20 tropical diseases. Ethiopia experiences a high burden of these diseases, but current access to diagnostics, medicine, and/or care has been little explored to inform the country's NTD strategic plan. The overall purpose of the scoping review was to map and characterize the burden of NTDs and challenges in access to diagnostics, medicine, and/or care in Ethiopia. Methods: A systematic search of evidence was conducted in PubMed, Cochrane Library, and Google Scholar from January 2000 until May 2022, without restrictions of language or study design. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Review was followed for screening of studies. Key findings were extracted and narrated qualitatively. Results: The search resulted in 4532 articles, of which 105 met the inclusion criteria and were included in the scoping review under three themes: burden of NTDs, access to diagnostics, medicine and/or care, and key barriers. Although gains have been made in the prevention and control of NTDs in Ethiopia, the burden remains high, and progress in access to diagnostics, medicine/drugs, and/or care is very slow. Poverty, poor quality of life, and underfunding of NTD programs decelerate the process of NTD elimination program in the country. Conclusions: The scoping review identified a considerable number of studies on the burden of NTDs in Ethiopia and strategies for diagnosis, treatment, and/or care; however, there is a paucity of evidence on the suitability and potential benefits of novel diagnostic technologies and medicines in the country. A regular review and analysis of such country-level evidence is important to inform the country NTDs roadmap and local implementation strategies. [ABSTRACT FROM AUTHOR]

Aim: To evaluate coverage of effective Kangaroo mother care (KMC) by developing a model that would result in high coverage (≥80%) of KMC for newborn weighing less than 2000 g at birth in Tigray region, Ethiopia. Methods: The study used formative research and continuous programme learning in iterative cycles of model development and modification conducted in close collaboration with the Tigray Regional Health Bureau. Quantitative methods were used to evaluate the various models. All study facilities were enrolled simultaneously, and hospitals and health centres were considered to become KMC‐providers. Results: The final scalable model implemented in two rural districts and one special urban zone of Tigray region attained the desired objective, with coverage of effective KMC of 82.3% at discharge. Conclusion: Achieving high coverage of KMC is possible through the design of context‐specific implementation strategies. The key factors for success were the commitment and strong leadership from the regional health bureau, strong linkages within the health system and between different departments within health facilities, improved health worker knowledge, skills and attitudes, hospitals and health centres that supported KMC performance, and systematic generation and use of data for continuous quality improvement. [ABSTRACT FROM AUTHOR]

Background: Mental disorders are becoming a growing public health problem worldwide, especially in low- and middle-income countries. Regular and adequate supplies of appropriate, safe, and affordable medications are required to provide quality mental health services. However, significant proportions of the population with severe mental disorders are not getting access to treatment. Among others, the availability and affordability of psychotropic medicines are significant barriers for many patients in meeting their medication needs. This study aimed to assess the availability, prices, and affordability of essential psychotropic medicines in the private and public health sectors of Addis Ababa, the capital city of Ethiopia. Methods: A cross-sectional study design was used in 60 retail medicine outlets from the public and private sectors. Stratified random and quota sampling were applied to select the retail outlets. Data was entered and analyzed using the preprogrammed WHO/HAI workbook and SPSS V.25. Results: The mean availability of Lower Priced Generic (LPG) psychotropic medicines was 24.33% in Addis Ababa (28.7% in the public sector and 19.80% in the private sector). The Patient prices for the LPG ranged from 0.52–6.43 MPRs in public and 1.08–24.28 MPRs in private sectors. Standard treatment costs varied from 0.1–7.8 days' wages in public and 0.8–25 days' wages in private sectors for the lowest-paid government worker to purchase a month's supply. Conclusions: Essential psychotropic medicines were poorly available, with high prices and low affordability in Addis Ababa. An efficient supply across all levels of care and financial protection for essential medicines should be in place to ensure access. [ABSTRACT FROM AUTHOR]

Background: In the Somali region of Ethiopia, visceral leishmaniasis (VL) is a public health concern. However, VL epidemiology and sand fly vectors have not been well studied in various areas of the regional state, including Denan district. Therefore, this study was conducted to determine the sero-prevalence, associated factors, and distribution of sand fly vectors of VL in Denan district, south-eastern Ethiopia. Methods: A facility-based cross-sectional study was conducted from April to September 2021 among VL patients with classic signs and symptoms visiting Denan Health Center in south-eastern Ethiopia. Using a convenience sampling method, 187 blood samples were collected from individuals who visited Denan Health Center during the study period. Blood samples were subjected to Direct Agglutination Test for the detection of antibodies to VL. A pre-tested structured questionnaire was also used to gather information on risk factors and other characteristics of knowledge and attitude assessment. Sand flies were also collected from indoor, peri-domestic, mixed forest, and termite mounds using light and sticky traps to determine the fauna and abundance. Results: The overall sero-prevalence rate was 9.63% (18/187). The sero-prevalence was significantly associated with outdoor sleeping (OR = 2.82), the presence of damp floors (OR = 7.76), and sleeping outdoor near animals (OR = 3.22). Around 53.48% of the study participants had previously heard about VL. Study participants practiced different VL control methods, including bed nets (42%), insecticide spraying (32%), smoking plant parts (14%), and environmental cleaning (8%). In total, 823 sand fly specimens, comprising 12 species in two genera (Phlebotomus and Sergentomyia), were trapped and identified. The most abundant species was Sergentomyia clydei (50.18%), followed by Phlebotomus orientalis (11.42%). Also, a higher proportion of P. orientalis was found in termite mounds (65.43%), followed by mixed forest (37.8%) and peri-domestic (20.83%) habitats. Conclusion: The study demonstrated a 9.63% sero-positivity of VL and a remarkable gap in knowledge, attitude, and practices towards VL. P. orientalis was also detected, which could be a probable vector in this area. Thus, public education should be prioritized to improve the community's awareness of VL and its public health impact. In addition, detailed epidemiological and entomological studies are recommended. [ABSTRACT FROM AUTHOR]

Background: Globalization in medical education often means a "brain drain" of desperately needed health professionals from low- to high-income countries. Despite the best intentions, partnerships that simply transport students to Western medical schools for training have shockingly low return rates. Ethiopia, for example, has sent hundreds of physicians abroad for specialty training over the past 30 years, the vast majority of whom have not returned. This represents a highly problematic net transfer of financial and human resources from the Ethiopian people to Western countries that have failed to develop their own adequate health human resource plans. Methods: With this background in mind, in 2003 Addis Ababa University invited the University of Toronto to collaborate on the first Ethiopian psychiatric residency program to be run entirely in Ethiopia. Called the Toronto Addis Ababa Psychiatry Project (TAAPP), it was established on the principle of supplementing the ability of the small Addis Ababa University Department of Psychiatry to teach, provide clinical supervision, and to help develop educational capacity. Over the last 6 years the model has involved a large number of University of Toronto faculty and residents who have spent blocks of 1 month each in Addis Ababa. Results: This article describes the first three phases of TAAPP (I) Development of a model residency program; (II) Enhancing clinical, educational and leadership capacity; and (III) Sustainability, faculty development, and continuing education. Between 2003 and 2009, the number of psychiatrists in Ethiopia increased from 11 to 34; the Addis Ababa University Department of Psychiatry faculty increased members from three to nine. There are new departments of psychiatry established in four other university hospitals in Ethiopia outside the capital city. Mental health services are now being integrated within the national system of primary care. Conclusion: An important issue that underscores such a partnership is the risk of simply exporting Western, America-centric psychiatric training versus creating culturally appropriate models of education.

Background: Adolescents have special sexual and reproductive health (ASRH) needs and are susceptible to poor health outcomes. The global burden of ill sexual health includes a significant proportion of Adolescents. The existing ASRH services in Ethiopia and particularly in the Afar region are currently not well suited to meet the needs of pastoralist adolescents. This study assesses the level of ASRH service utilization among pastoralists in Afar regional state, Ethiopia. Method: A community based cross-sectional study was conducted from January to March 2021 in four randomly chosen pastoralist villages or kebeles of Afar, Ethiopia. A multistage cluster sampling procedure was used to select 766 volunteer adolescents aged 10–19. SRH services uptake was measured asking whether they had used any SRH service components during the last year. Data was collected through face-to-face interviews with a structured questionnaire; data entry was done with Epi info 3.5.1. Logistic regression analyses was used to assess associations with SRH service uptake. SPSS version 23 statistical software package was used for advanced logistic regression analyses to assess the associations between dependent and predictor variables. Results: The study revealed that two-thirds or 513 (67%) of the respondents are aware of ASRH services. However, only one-fourth (24.5%) of the enrolled adolescents used at least one ASRH service in the past twelve months. ASRH services utilization was significantly associated with gender (being female [AOR = 1.87 (CI 1.29–2.70)], being in school [AOR = 2.38(CI: 1.05–5.41), better family income [AOR = 10.92 (CI; 7.10–16.80)], prior discussions of ASRH issues [AOR = 4.53(CI: 2.52, 8.16)], prior sexual exposure [AOR = 4.75(CI: 1.35–16.70)], and being aware of ASRH services [AOR = 1.96 (CI: 1.02–3.822)]. Being pastoralist, religious and cultural restrictions, fear of it becoming known by parents, services not being available, income, and lack of knowledge were found to deter ASRH service uptake. Conclusion: Addressing ASRH needs of pastoralist adolescents is more urgent than ever, sexual health problems are increasing where these groups face broad hurdles to SRH service uptake. Although Ethiopian national policy has created an enabling environment for ASRH, multiple implementation issues require special attention to such neglected groups. "Gender-culture-context-appropriate" interventions are favorable to identify and meet the diverse needs of Afar pastoralist adolescents. Afar regional education bureau and concerned stakeholders need to improve adolescent education to overcome social barriers (e.g. humiliation, disgrace, and deterring gender norms) against ASRH services through community outreach programs. In addition, economic empowerment, peer education, adolescent counseling, and parent-youth communication will help address sensitive ASRH issues. [ABSTRACT FROM AUTHOR]

Evidence of how R&D, innovation and productivity are intertwined in African countries like Ethiopia is quite limited. This study provides empirical evidence on the relationship between R&D, innovations, and productivity for Ethiopian firms using two rounds of the World Bank's Enterprise Survey dataset of year 2011 and 2015. We estimate firm-level productivity using a control function method, and the link between R&D, innovations, and productivity is estimated using the General Structural Equation Model (GSEM). We estimated for product and process innovations separately and jointly. The results show that innovations have a strong and positive impact on a firm's productivity in all estimation methods. Thus, innovative firms are more productive than their counterparts. However, the effect of R&D on innovations is positive and significant in GSEM estimation but not in other estimation methods. The findings also show that skilled labour and financial accessibility are key driving forces behind firms' engagement in R&D and innovative activities. Thus, there is a need to find a mechanism to promote firms' engagement in knowledge production, and design appropriate policies to enhance firm-level innovation initiatives. This study contributes to developing countries' empirical literature in terms of modelling the relationship between R&D, innovations, and firm productivity. [ABSTRACT FROM AUTHOR]

Background: Globally, Neisseria gonorrhoeae is the second most common cause of bacterial sexually transmitted diseases. The prominent predicament of this bacterium is its complications, non-susceptibility for many drugs, and aggravated transmission of other sexually transmitted infections. There is limited information about the prevalence, antibiotic resistance, and risk factors of N. gonorrhoeae in Tigrai, Ethiopia. Therefore, we aimed to determine the prevalence, antibiotic resistance, and risk factors of N. gonorrhoeae among patients attending non-profitable private clinics in Mekelle, Tigrai, Ethiopia. Methods: A cross-sectional study among 229 patients was conducted from February to June 2018. The socio-demographic data and associated factors were gathered using structured questionnaire, and swabs were taken from urethra and cervix of males and females, respectively. Specimens were inoculated on standard bacteriological culture media and antibiotic susceptibility testing was performed using Kirby-Bauer disc diffusion technique following the Clinical and Laboratory Standard Institute. Data were analyzed using Statistical Package for Social Sciences Version 21. The level of significance at p-value < 0.05 was considered statistically significant. Results: The overall prevalence of N. gonorrhoeae was 23 (10.04%). High prevalence rates of N. gonorrhoeae were observed in females, urban residents and married ones. N. gonorrhoeae had shown statistically significant association with HIV positive, previous history of STIs, shisha users, Khat (Catha edulis) users, condom non-users and having more than two sexual partners. All isolates showed resistance to penicillin followed by tetracycline 16 (69.6%) and ciprofloxacin 8 (34.8%). Four isolates (7.4%) exhibited resistance to azithromycin with no resistance to ceftriaxone. Twelve (52.2%) isolates showed multidrug resistance (MDR). Conclusions: The prevalence of N. gonorrhoeae and drug resistance, including multidrug resistance, was high in the study. Multiple factors were associated with the acquisition of N. gonorrhoeae. Therefore, behavioral change and communication should be strengthened. [ABSTRACT FROM AUTHOR]

Honey is one of the important food commodities due to its nutritional and medicinal values. However, the issue of its quality and authenticity remain as important factors in consumption and marketing. This study was aimed at determining the botanical sources and quality parameters of honey samples collected from different areas of Ethiopia. The botanical sources of honey were analyzed using the melissopalynological method. Sugar profiles were analyzed using HPLC, and physicochemical properties were determined following the harmonized methods of honey analysis. Diverse plant species, including Schefflera abyssinica, Eucalyptus spp., Guizotia abyssinica., Echinops spp., Coffee arabica, Bersama abyssinica, and Rumex spp., were identified as dominant sources of honey. However, honey from the Gimbo district contains no pollen fingerprints, and its source has remained unknown. The average values of honey sugar compositions ranged from 30.3–46.7%, 29.9–40.3%, 15.0–22.2%, and 0.28–4.4% for fructose, glucose, sucrose, and maltose, respectively. Although the quality parameter values of most honeys fit the acceptable range of national and international honey quality standards, honeys collected from Guassa district revealed some abnormal characteristics. This abnormality may be related with poor handling, processing, or suspected for honey adulteration. Thus, regular testing and monitoring of honey quality are crucial in order to maintain its natural properties as well as control the current widespread practice of honey adulteration in Ethiopia. [ABSTRACT FROM AUTHOR]

Background: Exposure to armed conflicts result in strongly adverse and often irreversible short- and long-term effects which may transmit across generations. Armed conflicts directly cause food insecurity and starvation by disruption and destruction of food systems, reduce farming populations, destroying infrastructure, reducing resilience, and increasing vulnerabilities, disruptions in access to market, increasing food price or making goods and services unavailable altogether. The objective of the present study was to determine the status of household food insecurity in the armed conflict affected communities of Tigray in terms of Access, Experience and Hunger scale. Method: Community-based cross-sectional study was conducted to assess impact of armed conflict on household food insecurity among households with children with under one year. FHI 360 and FAO guidelines were used to quantify household food insecurity and Household hunger status. Results: Three-fourth of the households had anxiety about food supply and eat undesired monotonous diet due to lack of resources. Households were obliged to eat few kinds of foods, eat smaller meals, eat foods they do not want to eat, or went a whole day without eating any food. Household food insecurity access, food insecurity experience, and hunger scales significantly increased by 43.3 (95% CI: 41.9–44.7), 41.9 (95% CI: 40.5–43.3) and 32.5 (95% CI: 31.0-33.9) percentage points from the prewar period. Conclusions: Household food insecurity levels and household hunger status of the study communities was unacceptably high. The armed conflict has significant negative effect on food security in Tigray. It is recommended that the study communities need to be protected from the immediate and long-term consequences of conflict-induced household food insecurity. [ABSTRACT FROM AUTHOR]

Background: Although menstruation is a biological phenomenon, it is still subjected to secrecy, shame, and negativity. Schoolgirls lack access to appropriate sources of information about menstruation. Little is known about the content of the information provided to schoolgirls concerning menstruation in northern Ethiopia. This study explored schoolgirls' experiences and the content of information they receive concerning menstrual hygiene management in Tigray. Methods: A qualitative design was implemented. Focus group discussions and in-depth interviews were conducted using the local language among 79 schoolgirls who had experienced menarche. Data were audio-recorded, transcribed, translated, and imported into ATLAS.ti-7.5.18 computer software for analysis. Data were coded and analyzed using a thematic analysis. Results: Five themes have emerged from the analysis: 1) there is an indistinct and haphazard source of menstrual information; 2) menstruation is perceived as "a natural gift"; 3) menstruation is also considered fearful and embarrassing; 4) negative community perceptions of menstruation lead to menstrual restrictions, and 5) lack of privacy for dealing with menstrual issues as well as the scarcity of menstrual hygiene management materials is an on going problem. Schoolgirls have indistinct and haphazard sources of information concerning menstrual hygiene management, obtaining it from teachers, mothers, sisters, and friends, but the information they receive is shrouded in secrecy and often is factually incorrect. Menstruation is commonly linked to notions of sexuality, shame, and the approach of marriageability. Conclusion: The information that schoolgirls in rural Tigray receive about menstrual hygiene management is inaccurate, insufficient, and encumbered with social taboos. Thus, schoolgirls do not have an adequate understanding of the physiology of menstruation and do not receive adequate emotional support at menarche, leaving them with feelings of embarrassment and anxiety. There should be efforts to implement programs that change community perceptions about menstruation. [ABSTRACT FROM AUTHOR]

Back ground: HIV/AIDS remained among the common public health problems in developing country. Despite the extensive delivery of ART and improved coverage of the service access, still, man-made problems like war have negatively influenced the utilization of antiretroviral treatment services. The war in Tigray Region in the northern Ethiopia broke out in November 2020 and thereby has brought about an extreme damage on most of the infrastructure in Tigray, including the health institutions. The purpose of this study is, therefore, to assess and report the trend of HIV service provision across the war affected rural health facilities in Tigray. Methods: The study was conducted in 33 rural health facilities during the active war in Tigray. A facility based retrospective cross-sectional study design was conducted among health facilities from July 03 to August 05, 2021. Result: A total of 33 health facilities from 25 rural districts were included in the HIV service delivery assessment. A total of 3274 and 3298 HIV patients were seen during pre-war period in September and October 2020, respectively. The number of follow-up patients during the war period in January remained to be only 847(25%) which is significantly reduced with a P value<0.001. A similar trend was observed during the subsequent months until May. The trend of follow-up patients on ART significantly declined from 1940 in September (pre-war) to 331(16.6%) in May (during the war). This study also revealed a 95.5% reduction of laboratory service provision to HIV/AIDS patients during the war in January and with similar trends thereafter (P<0.001). Conclusion: The war has led to a significant decline of HIV service provision in the rural health facilities and most part of the region during the first eight months of active war in Tigray. [ABSTRACT FROM AUTHOR]

Introduction: Despite the high expectations of electronic medical records as a great prospect for improving performance in healthcare, the level of adoption and utilization, particularly in a developing country, is low. Knowing the willingness to use the electronic medical record system in the private hospital has an impact on the future implementation status and utilization of the electronic medical record in Ethiopia. However, there was no evidence of the status of the willingness to use electronic medical record systems in private hospitals in the Amhara region. This study aimed to assess the willingness to use electronic medical record Systems and its associated factors among health professionals working in Amhara Region Private Hospitals. Methods: A cross-sectional institutional study was performed among 406 health professionals selected using proportional allocation with a simple random sampling technique in Amhara region private hospitals by using self-administered structured questionnaires. The data were analyzed using SPSS version 20 software. Descriptive statistics and binary logistic regression were performed to estimate the crude and adjusted odds ratios with a 95% Confidence interval. Results: Out of the 406 participants included in the analysis, 307 (75.6%) showed a willingness to use the electronic medical record system. About three hundred twelve (76.8%) health professionals had good knowledge of electronic medical record systems, and 257 (63.3%) had good computer skills in electronic medical record systems. Health professionals who had electronic medical record knowledge (AOR = 1.85, 95% CI (1.004–3.409)), EMR training (3.29, 95% CI (1.353–8.003)), technical support personnel (1.92, 95% CI (1.122–3.305)), supportive supervision (AOR = 1.97, 95% CI (1.072–3.628)), and computer skill on electronic medical record (1.77, 95% CI (1.002–3.148)) were significantly associated with the outcome variable. Conclusions: This finding shows a good proportion of willingness to use the electronic medical record system. The most significant factors associated with willingness to use the electronic medical record system were a lack of computer skills, computer training, and knowledge of the electronic medical record system. [ABSTRACT FROM AUTHOR]

This study investigated the effect of gravel and cobblestone road surfaces on runoff responses and sediment yield in semi-arid northern Ethiopia. A field experiment was set up with six treatments of gravel and cobblestone road surfaces at 1, 3 and 7% slope gradients. Cobblestone road surface produced significantly lower runoff than gravel. Slope gradient had a significant effect on the runoff amount from gravel and cobblestone road surfaces. Runoff reductions by cobblestone road surface compared to gravel at 1, 3 and 7% slopes were 27, 30 and 31%, respectively. Runoff coefficients for gravel road surface at 1, 3, and 7% slopes were 0.60, 0.65 and 0.68, respectively. Runoff coefficients for cobblestone at 1, 3 and 7% slopes were 0.41, 0.45 and 0.47, respectively. Slope gradient had a significant effect on sediment yield for a gravel road surface. Sediment yield from cobblestone, however, was insignificant compared to gravel. [ABSTRACT FROM AUTHOR]

Background: Kangaroo mother care is a proven intervention shown to be effective in reducing neonatal mortality among low-birth-weight infants. The paucity of evidence regarding the practice at home can be highlighted. This study aimed to assess the practice and outcome of kangaroo mother care at home among mothers having low-birth-weight infants discharged from two hospitals in Mekelle, Tigray, Ethiopia. Methods: A prospective cohort study was conducted among 101 paired mothers and low-birth-weight neonates discharged from Ayder and Mekelle Hospitals. Non-probability purposive sampling was used to select 101 infants. Data were collected from patient charts in both hospitals using interviewer-administered structured questionnaire, anthropometric measurements and were then analyzed using SPSS version 20. Characteristics were analyzed using descriptive statistics. Bivariate analysis was used, and variables with p-value < 0.25 were exported to multivariable logistic regression and statistical significance was set at a p-value < 0.05. Results: Kangaroo mother care was continued at home in 99% of the infants. Three of the 101 infants died before the age of 4 months with a possible cause of death from respiratory failure. Exclusive breastfeeding was provided for 67% of the infants, and it was higher in infants who started kangaroo mother care within 24 hours of life (AOR 3.8, 95% CI 1.07– 13.25). Malnutrition was higher in those with birth weight < 1500 grams (AOR 7.3,95% CI 1.63– 32.59); small for gestational age (AOR 4.8,95% CI 1.41– 16.31) and those provided kangaroo mother care for < 8 hours per day (AOR 4.5,95% CI 1.40– 16.31). Conclusion: Early initiation and prolonged duration of kangaroo mother care were associated with increased exclusive breastfeeding practice and decreased incidence of malnutrition. Kangaroo mother care should be promoted at the community level. [ABSTRACT FROM AUTHOR]

Background: Although Ethiopia is endemic to viral hepatitis and HIV, data that could guide population-specific interventions are limited. In this study, we determined the seroprevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) and assessed their associations with HIV-1 viral load suppression among HIV-1 infected patients on antiretroviral therapy (ART) at Mekelle hospital in northern Ethiopia. Methods: Between February and April 2020, blood samples were collected from 439 participants. Samples were screened for HBsAg and anti-HCV on the immunochromatographic test and confirmed using the Enzyme-Linked Immuno-sorbent assay (Beijing Wantai Co. China). HIV-1 viral load was quantified using reverse transcription-polymerase chain reaction (RT-PCR) on the Abbott platform. Binary and multivariable logistic regression was performed to identify potential predictors. Results: Overall, 10% (44/439) and 3.6% (16/439) of the participants were coinfected with HBV and HCV, respectively. In a multivariate analysis, being illiterate (AOR = 6.57; 95% CI 1.04–41.6), and having a history of sexually transmitted infections (AOR = 4.44; 95% CI 1.31–15.0) and multiple sexual partners (AOR = 29.9; 95% CI 7.82–114.8) were associated with HBV infection. On the other hand, participants with a history of chronic non-communicable diseases (AOR = 10.6, 95% CI 1.61–70.1), and those reporting a history of sexually transmitted infections (AOR = 5.21, 95% CI 1.39–19.5) were more likely to be infected with HCV. In further analysis, HCV infection status was significantly associated with decreased viral load suppression rate (AOR = 7.14; 95% CI 2.18–23.3) whereas no significant association was observed with the HBV infection. Conclusions: The HBV coinfection rate in our study is high and, as per WHO's standard, corresponds to a hyperendemic level. The HCV coinfection rate is also substantially high and urges attention given its influence on the viral load suppression of HIV patients on ART at our study site. Our findings suggest the need to adopt universal screening and vaccination of people with HIV against HBV and screening for HCV at our study site and in Ethiopia at large, which contributes to Ethiopia's progress towards the 2030 global target of reducing the HBV infection. [ABSTRACT FROM AUTHOR]

Background: In Ethiopia, quality of maternal and newborn care is poor. This situation has persisted, despite the wide implementation of several capacity building-oriented interventions including clinical mentoring for skilled birth attendants that were anticipated to translate in to high–quality maternal and newborn care on each encounter. The effectiveness of mentoring programs is not yet well documented in the research literature. Therefore, we evaluated the effect of a catchment based clinical mentorship in improving the quality of maternal and newborn care in primary level facilities of Tigray, Northern Ethiopia. Methods: We conducted a controlled quasi-experimental pre-post study among 19 primary health care facilities, with 10 facilities assigned to the group where the catchment based clinical mentorship program was implemented (intervention group), and 9 facilities to the control group. We assigned the group based on administrative criteria, number of deliveries in each facility, accessibility, and ease of implementation of the intervention. A sample of 1320 women(662 at baseline; 658 at post intervention) and 233 skilled birth attendants(121 at baseline and 112 at end line) were included. We collected data from mothers, skilled birth attendants and facilities. The first round of data collection (baseline) took place two weeks prior the inauguration of the intervention, 05 October to 04 November 2019. The end line data collection occurred from 22 May to 03 July 2020. The primary Outcome was "receipt quality of maternal/newborn care". We analyzed the data using difference in differences (DiD) and logistic regression with Generalized Estimating Equation. The level of significance of predictors was declared at p-value less than 0.05in the multivariable analysis. Intervention: We deployed a team of local clinical mentors working at primary hospitals to provide clinical mentorship, and direct feedback in routine and emergency obstetrical and newborn care to the mentees (all skilled birth attendants performing maternal and newborn health services) functioning in their catchment rural health centers for duration of six months. While visiting a facility, mentors remain at the facility each lasting at least five to seven days per month, over the course of intervention period. Results: A significantly higher proportion of women at intervention facilities received quality of care services, compared with women at comparison facilities. (DiD = 18.4%, p<0.001). Moreover, following the implementation of the intervention we detected a difference in the occurrences of maternal complication outcome during delivery and immediately after birth. This was decreased by 4.5%, with significant differences between intervention and comparison sites (DiD = 4.5%, p = 0.013). We also found a favorable difference in occurrences of neonatal obstetric complications, with a decrease of 4.8% in the intervention site and almost no change in the comparison site (DiD = 4.8%, p = 0.002). Among the determinants of quality of care, we found that providers' job satisfaction (AoR = 2.95, 95%CI: 1.26 to 6.91), and making case presentation at regular basis(AoR = 1.89, 95%CI: 1.05 to 3.39) were significantly associated to improve the quality of care. However, delivery load(AoR = 0.95, 95%CI: 0.93 to 0.98) was negatively associated with quality of care. Conclusions: We conclude that the catchment based clinical mentorship intervention is effective to improve quality of care and reduce childbirth complications in northern Ethiopia. This finding further elaborated that incorporating maternal and newborn health catchment based clinical mentorship activities into the existing health system strengthening strategies can catalyze improvement processes to quality practice and health systems. This is seen as a necessary step to achieve the effective quality universal health care required to meet the health-related Sustainable Development Goals. Besides, more attention needs to be given to develop interventions and strategies that directly enhance providers' job satisfaction and reduce delivery work load. [ABSTRACT FROM AUTHOR]

The lack of safe drinking water affects communities in low-to-medium-income countries most. This barrier can be overcome by using sustainable point-of-use water treatments. Solar energy has been used to disinfect water for decades, and several efforts have been made to optimise the standard procedure of solar water disinfection (SODIS process). However, the Health Impact Assessment of implementing advanced technologies in the field is also a critical step in evaluating the success of the optimisation. This work reports a sustainable scaling-up of SODIS from standard 2 L bottles to 25 L transparent jerrycans (TJC) and a 12-month field implementation in four sites of Tigray in Ethiopia, where 80.5% of the population lives without reliable access to safe drinking water and whose initial baseline average rate of diarrhoeal disease in children under 5 years was 13.5%. The UVA dose required for 3-log reduction of E. coli was always lower than the minimum UVA daily dose received in Tigray (9411 ± 55 Wh/m2). Results confirmed a similar decrease in cases of diarrhoea in children in the implementation (25 L PET TJC) and control (2 L PET bottles) groups, supporting the feasibility of increasing the volume of the SODIS water containers to produce safer drinking water with a sustainable and user-friendly process. [ABSTRACT FROM AUTHOR]

Background. Dental caries is a major public oral infectious disease globally due to its high prevalence and significant social impact. Many studies have been conducted on dental caries in Ethiopia; however, they fail to convey the antimicrobial resistance in the oral environment. Objective. This study was conducted to determine the antimicrobial susceptibility patterns and biofilm formation in the bacteria isolated from dental caries and its associated factors of dental caries in THE Ayder Comprehensive Specialized Hospital and private dental clinics located at Mekelle, Ethiopia. Methods. A cross-sectional study was conducted from September 2019 to October 2020. Sociodemographic characteristic, behavioral, and clinical data were collected using structured questionnaires. A total of 422 dental caries-suspected patients were selected and coronal caries scraps were collected by the dentist aseptically; these samples were transported to a microbiological laboratory to identify the antibiotic sensitivity assay and biofilm formation by the isolated pathogens. The data was analyzed using SPSS version 22. The P value of ≤0.05 was considered statistically significant. Results. The overall prevalence of culture-positive samples was found to be 196 (46.4%). From the 196 culture-positive samples, 327 bacteria were isolated. Out of 327 bacterial isolates, 196 (46.4%) were identified as Streptococcus mutans and 69 (35.2%) were identified to be Staphylococcus aureus. From the isolated bacteria, 311 (95.1%) organisms were identified as positive for biofilm formation. From the AST assay, we have identified that penicillin has the highest resistance rate of 76.5%, followed by tetracycline at 64.8%. In contrast, the antibiotics such as cefoxitin and chloramphenicol have a sensitivity of 83.5% and 81.6% to all the bacterial isolates. The overall prevalence of multidrug resistance (MDR) in the isolates was found to be 40.4%. With respect to the associated risk factors, the white spot (AOR = 3.885 , 95% CI 1.282-11.767, P = 0.016), gum bleeding (AOR = 2.820 , 95% CI 1.006-7.907, P = 0.049), toothache (AOR = 2.27 , 95% CI 0.58-0.885, P = 0.033), and chocolate consumption (AOR = 5.314 , 95% CI 1.760-16.040, P = 0.003) were statically associated with dental caries bacterial infection. Conclusion. Based on our findings, we recommend the integration of routine culture and AST into clinical practice that might support the diagnosis and management of MDR in dental caries. The education on proper dietary habits might support the prevention and control of dental caries. It is important to provide health education on how to improve oral health in the study area. The education on proper dietary habits might support the prevention and control of dental caries. Further study is needed to find the other determinant factors of dental caries. [ABSTRACT FROM AUTHOR]

Introduction: In resource-limited settings incorporating the Telemedicine system into the healthcare system enhances exchanging valid health information for practicing evidence-based medicine for the diagnosis, treatment, and prevention of diseases. Despite its great importance, the adoption of telemedicine in low-income country settings, like Ethiopia, was lagging and increasingly failed. Assessing the readiness of health professionals before the actual adoption of telemedicine is considered the prominent solution to tackle the problem. However, little is known about Health professionals' telemedicine readiness in this study setting. Objective: Accordingly, this study aimed to assess health professionals' readiness and its associated factors to implement a Telemedicine system at private hospitals in North West, Ethiopia. Materials and methods: An institution-based cross-sectional study was conducted from March 3 to April 7, 2021. A total of 423 health professionals working in private hospitals were selected using a simple random sampling technique. Multi-variable logistic regression was fitted to identify determinant factors of health professional readiness after the other covariates were controlled. Result: In this study the overall readiness of telemedicine adoption was 65.4% (n = 268) [95% CI:60.1–69.8]. Knowledge (AOR = 2.5;95% CI: [1.4, 4.6]), Attitude (AOR = 3.2;95% CI: [1.6, 6.2]), computer literacy (AOR = 2.2; 95% CI: [1.3, 3.9]), computer training (AOR = 2.1;95% CI: [1.1, 4.1]), Computer skill (AOR = 1.9;95% CI: [1.1, 3.4]), computer access at office (AOR = 2.1;95% CI: [1.1, 3.7]), Internet access at office (AOR = 2.8; 95% CI: [1.6, 5.1]), Own personal computer (AOR = 3.0; 95% CI: [1.5, 5.9]) and work experience (AOR = 3.1; 95% CI: [1.4, 6.7]) were significantly associated with the overall health professionals readiness for the adoption of telemedicine using a cut point of p-value lessthan 0.05. Conclusion and recommendation: Around two-thirds of the respondents had a good level of overall readiness for the adoption of telemedicine. The finding implied that less effort is required to improve readiness before the implementation of telemedicine. This findings implied that respondents who had good knowledge and a favorable attitude toward telemedicine were more ready for such technology. Capacity building is needed Enhance computer literacy, and computer skills building their confidence to rise ready for such technology. Building their capacity through training, building good internet connection, and availability of computers, where the necessary measures to improve Telemedicine readiness in this setting. Additionally, further studies are recommended to encompass all types of telemedicine readiness such as organizational readiness, technology readiness, societal readiness, and so on. Additionally, exploring the healthcare provider opinion with qualitative study and extending the proposed study to other implementation settings are recommended to be addressed in future works. The study has a positive impact on the successful implementation and use of telemedicine throughout hospitals at countries level by providing pertinent information about health professionals' preparedness status. Therefore, implementing telemedicine will have a significant contribution to the health system performance improvement in terms of providing quality care, accessibility to health facilities, reduction of costs, and creating a platform for communication between health professionals across different health institutions for providing quality patient care. [ABSTRACT FROM AUTHOR]

Black cotton soils, which are expansive, are present in abundance in Ethiopia. This type of soil possesses expansion when saturated with water and contraction during hot seasons, due to which it is labelled as "weak soil." They may remain a threat to the structures if they are constructed over them without precautions. The quality of such soils can be improved by treating them with suitable stabilizers or soil reinforcers. This paper discusses the chances of using the second waste of plastic bottles as a reinforcer to strengthen weak black cotton soils in Ethiopia. Second, plastic bottle waste was added at 1%, 2%, 3%, 5%, 7%, and 9% to the soil, and numerous trials were conducted to ensure the reliability of the results. The effects were analyzed based on the results from the Atterberg limit tests, compaction tests, unconfined compression strength (UCS) tests, and the California bearing ratio test (CBR) for soaked and unsoaked conditions. The results were compared against the natural soil results, and the optimum usage percentage of second waste plastic required to reinforce the soil was reported. The results indicate that among the various properties used, the mix with 2% second waste plastic is effective with numerous trials being conducted to ensure the reliability of the results and decreased values of OMC by 18.5%, increased MDD by 1.9%, increased CBR by 50.9%, and increased UCS by 10.1%. Thus, the research provides a novel technique to recycle plastic waste once again as soil reinforcement, thereby saving the environment from dumped waste. [ABSTRACT FROM AUTHOR]

Background: Distribution of schistosomiasis is more focal due to spatial heterogeneities in intermediate host snail dynamics and water contact behavior of humans. This makes the search for new transmission foci of schistosomiasis and its connection with malacologically receptive water bodies essential for effective control of its transmission. This study was intended to assess the prevalence of intestinal helminth infections among schoolchildren and Schistosoma mansoni transmission in Koga irrigation scheme surroundings, northwest Ethiopia. Materials and methods: Cross-sectional parasitological and malacological surveys were conducted in three schools and nearby water bodies, respectively around Koga irrigation scheme. Stool specimens were collected from 421 randomly selected schoolchildren and microscopically examined using Kato-Katz and formol-ether concentration methods. Malacological surveys were carried out and the identified Biomphalaria pfeifferi snails were screened for schistosome infection. Swiss albino mice were exposed to schistosome cercariae shed by Biomphalaria pfeifferi for definite identification of Schistosoma species. Results: Among the examined schoolchildren, 22.6% (95% CI: 18.7%-26.9%) were positive for at least one intestinal helminths species. Ascaris lumbricoides was the most frequent intestinal helminth detected among forty (9.5%) children. Schistosoma mansoni was detected among 4.8% (95% CI: 2.9%-7.2%) of children and its prevalence was significantly higher among male children (p = 0.038) and those attending in Mengesha Jemberie Primary School (p = 0.044). Biomphalaria pfeifferi snails were identified in water bodies in close proximity to Mengesha Jemberie and Wotete Abay Primay schools. Schistosoma mansoni adult worms were harvested after exposure of mice to cercariae shed from Biomphalaria pfeifferi snails collected from water bodies nearby Mengesha Jemberie Primary School. Conclusions: Schistosoma mansoni infection of schoolchildren, findings of schistosome infected snails and establishment of mice infection confirm that transmission is taking place in the study areas. Hence, snail control and other measures such as provision of sanitary facilities and health education are recommended. [ABSTRACT FROM AUTHOR]

Background: COVID-19 is one of the leading causes of morbidity and mortality and is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). A patient infected with SARS-CoV-2 is said to be recovered from the infection following negative test results and when signs and symptoms disappear. Different studies have shown different median recovery time of patients with COVID-19 and it varies across settings and disease status. This study aimed to assess time to recovery and its predictors among severely ill COVID-19 patients in Tigray. Methods: A total of 139 severely ill COVID-19 patients who were hospitalized between May 7, 2020 and October 28, 2020 were retrospectively analyzed. Cox proportional hazard regression model was fitted to identify the risk factors associated with the time duration to recovery from severe COVID-19 illness. Results: The median age of the patients was 35 years (IQR, 27– 60). Eighty-three (59.7%) patients recovered with a median time of 26 days (95% CI: 23– 27). The results from the multivariable analysis showed that the recovery time was lower for severely ill patients who had no underline comorbidity diseases (AHR=2.48, 95% CI: 1.18– 5.24), shortness of breath (AHR=2.08, 95% CI: 1.07– 3.98) and body weakness (AHR=2.62, 95% CI: 1.20– 5.72). Moreover, COVID-19 patients aged younger than 40 years had lower recovery time compared to patients aged 60 and above (AHR=4.09, 95% CI: 1.58– 10.61). Conclusion: The median recovery time of severely ill COVID-19 patients was long, and older age, comorbidity, shortness of breath, and body weakness were significant factors related with the time to recovery among the severely ill COVID-19 patients. Therefore, we recommended that elders and individuals with at least one comorbidity disease have to get due attention to prevent infection by the virus. Moreover, attention should be given in the treatment practice for individuals who had shortness of breath and body weakness symptoms. [ABSTRACT FROM AUTHOR]

This study uncovers controversies about the use of mother tongue as a medium of instruction in Ethiopia. It examines motives for the use of the mother tongue as a medium of instruction at the elementary level, and on which grounds the rights of minority linguistic groups to be instructed in their mother tongue are overlooked. To this effect, data were gathered from government language policy-related documents as well as 28 purposefully selected key informants through in-depth interviews. The data were analysed through a critical discourse analysis approach. Data showed that the government uses mother-tongue education for political motives and has the power to put its political interests into practice without conducting any societal needs assessments. On the other hand, the government lacks commitment to putting its language-use ideology into practice. It has used only some of the languages as mediums of instruction, with the result that many children of minority groups are not learning their daily lessons effectively. The study recommends that the government should confirm the right to learn through mother-tongue instruction at an elementary level to benefit children so that they can enjoy the opportunities of learning in their languages. [ABSTRACT FROM AUTHOR]

Background: Ethiopia federal ministry of health has been working on increasing access to immunization service by deploying solar refrigerators to primary health care facilities. However, there is limited evidence on cold chain and vaccine management status. Therefore, the objective of this study was to assess knowledge of vaccine handlers and status of cold chain and vaccine management and their associated factors in primary health care facilities of Tigray region Northern Ethiopia. Methods: Institutional based cross-sectional study was conducted in four randomly selected districts of Tigray region, Northern Ethiopia. In each selected district, all primary health care facilities with functional vaccine refrigerators were included in the study. Data were collected using a pre-tested semi-structured questionnaire. The collected data were entered into Epi-data version 3.1 and then exported to Statistical Package for Social Sciences (SPSS) version 21 for analysis. All variables with p-value of < 0.25 in bivariate logistic regression analysis were included in multi-variable model to identify predictors of the dependent variables. Results: In this study, fifty Primary Health Care Facilities (PHCFs) were included with a response rate of 94.4%. The overall level of good knowledge of vaccine handlers and good status of cold chain and vaccine management were 48% (95% CI; 30.7%-62%) and 46% (95%CI; 26.1%-61.3%) respectively. Receiving training on cold chain and vaccine management (AOR = 5.18; 95%CI: 1.48–18.18) was significantly associated with knowledge of vaccine handlers. Furthermore, receiving supportive supervision (AOR = 4.58; 95%CI: 1.04–20.17) and good knowledge of vaccine handlers (AOR = 10.97; 95%CI: 2.67–45.07) were significant associated with cold chain and vaccine management. Conclusions: This study showed that knowledge of vaccine handlers on cold chain and vaccine management was poor. Similarly, the cold chain and vaccine management status was also poor. Therefore, on-site training should be provided to vaccine handlers to increase their knowledge, so as to improve their practices on cold chain and vaccine management. In addition, Programme based supportive supervision is needed to improve cold chain and vaccine management. [ABSTRACT FROM AUTHOR]