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Since the downfall of the dictatorship, Hungary's approach to migration, traditionally a liberal one, is now mainly shaped by the country's intention to be reintegrated into Europe and, to have its migration practice harmonized with that of the Western democracies. Decision, makers in Budapest show no great concern about emigration, which is expected to remain relatively insignificant. Attention is therefore concentrated on the possibility of a massive influx of immigrants, especially from the neighboring states. This could easily undermine Hungary's political stability and economic development. The question of international migration can be addressed only in an all-European framework. Experts are convinced that migratory pressures originating in Eastern and Central Europe could be considerably limited by measures taken to guarantee the rights of ethnic minorities. [ABSTRACT FROM AUTHOR]

Epidemiological and genetic data support the notion that schizophrenia and bipolar disorder share genetic risk factors. In our previous genome-wide association study, meta-analysis and follow-up (totaling as many as 18 206 cases and 42 536 controls), we identified four loci showing genome-wide significant association with schizophrenia. Here we consider a mixed schizophrenia and bipolar disorder (psychosis) phenotype (addition of 7469 bipolar disorder cases, 1535 schizophrenia cases, 333 other psychosis cases, 808 unaffected family members and 46 160 controls). Combined analysis reveals a novel variant at 16p11.2 showing genome-wide significant association (rs4583255[T]; odds ratio=1.08; P=6.6 × 10(-11)). The new variant is located within a 593-kb region that substantially increases risk of psychosis when duplicated. In line with the association of the duplication with reduced body mass index (BMI), rs4583255[T] is also associated with lower BMI (P=0.0039 in the public GIANT consortium data set; P=0.00047 in 22 651 additional Icelanders).