1. A study of labetalol in patients of European, West Indian and West African origin.
- Author
-
Jennings K and Parsons V
- Subjects
- Adult, Africa, Western, Aged, Blood Pressure drug effects, Drug Evaluation, Drug Resistance, Europe, Humans, Hypertension epidemiology, Hypertension physiopathology, Labetalol adverse effects, Labetalol pharmacology, Middle Aged, West Indies, Black People, Ethanolamines therapeutic use, Hypertension drug therapy, Labetalol therapeutic use, White People
- Abstract
1 Hypertension in West Indians and Africans is common and has an unacceptably high mortality in the younger patients. 2 Fifty-three patients received labetalol (a combined alpha- and beta-adrenoreceptor antagonist) as part of an open evaluation of its anti-hypertensive effect. Ten non-caucasian patients were included. 3 Significant reductions in systolic and diastolic pressures were obtained in the caucasian patients, the African and West Indian patients remaining refractory to therapy.
- Published
- 1976