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Highlights from the article: Front Cover: Asmic Isocyanide-Nitrile Isomerization-Alkylations (Eur. J. Org. After Asmic is decorated through alkylations (the gymnast on the left), an isocyanide to nitrile isomerization is triggered by the use of I n i BuLi, expelling a transient carbene which receive a reoriented cyanide to afford a lithiated nitrile, whose alkylation leads to a quaternary nitrile (the gymnast with a winning stance on the right). After Asmic is decorated through alkylations (the gymnast on the left), an isocyanide to nitrile isomerization is triggered by the use of I n i BuLi, expelling a transient carbene which receive a reoriented cyanide to afford a lithiated nitrile, whose alkylation leads to a quaternary nitrile (the gymnast with a winning stance on the right).