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1. Non-synonymous variant (Gly307Ser) in CD226 is associated with susceptibility to multiple autoimmune diseases.

Author

Maiti, Amit K., Kim-Howard, Xana, Viswanathan, Parvathi, Guillén, Laura, Qian, Xiaoxia, Rojas-Villarraga, Adriana, Sun, Celi, Cañas, Carlos, Tobón, Gabriel J., Matsuda, Koichi, Shen, Nan, Cherñavsky, Alejandra C., Anaya, Juan-Manuel, and Nath, Swapan K.

Subjects
*AUTOIMMUNITY, *GENETIC polymorphisms
Abstract

Objectives. Recently, a non-synonymous (Gly307Ser) variant, rs763361, in the CD226 gene was shown to be associated with multiple autoimmune diseases (ADs) in European Caucasian populations. However, shared autoimmunity with CD226 has not been evaluated in non-European populations. The aim of the present study is to assess the association of this single nucleotide polymorphism (SNP) with ADs in non-European populations. [ABSTRACT FROM PUBLISHER]

Published
2010
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